1.0 2016-09-30 23:29:48 UTC 2020-05-21 16:26:21 UTC BMDB0007065 BMDB07065 DG(14:1(9Z)/24:1(15Z)/0:0) DG(14:1(9Z)/24:1(15Z)/0:0), also known as dg(14:1(9z)/24:1(15z)/0:0) or DAG(14:1/24:1), belongs to the class of organic compounds known as 1,2-dg(14:1(9z)/24:1(15z)/0:0)s. These are dg(14:1(9z)/24:1(15z)/0:0)s containing a glycerol acylated at positions 1 and 2. DG(14:1(9Z)/24:1(15Z)/0:0) is possibly soluble (in water) and an extremely weak basic (essentially neutral) compound (based on its pKa). DG(14:1(9Z)/24:1(15Z)/0:0) participates in a number of enzymatic reactions, within cattle. In particular, DG(14:1(9Z)/24:1(15Z)/0:0) can be biosynthesized from PA(14:1(9Z)/24:1(15Z)); which is mediated by the enzyme phosphatidate phosphatase. Furthermore, DG(14:1(9Z)/24:1(15Z)/0:0) and nervonoyl-CoA can be converted into TG(14:1(9Z)/24:1(15Z)/24:1(15Z)) through its interaction with the enzyme dg(14:1(9z)/24:1(15z)/0:0) O-acyltransferase. Finally, CDP-Ethanolamine and DG(14:1(9Z)/24:1(15Z)/0:0) can be converted into cytidine monophosphate and PE(14:1(9Z)/24:1(15Z)); which is mediated by the enzyme choline/ethanolaminephosphotransferase. In cattle, DG(14:1(9Z)/24:1(15Z)/0:0) is involved in a couple of metabolic pathways, which include de novo triacylglycerol biosynthesis TG(14:1(9Z)/24:1(15Z)/24:1(15Z)) pathway and phosphatidylethanolamine biosynthesis pe(14:1(9Z)/24:1(15Z)) pathway. 1-Myristoleoyl-2-nervonoyl-sn-glycerol DAG(14:1/24:1) DAG(14:1N5/24:1N9) DAG(14:1W5/24:1W9) DAG(38:2) DG(14:1/24:1) DG(14:1N5/24:1N9) DG(14:1W5/24:1W9) DG(38:2) Diacylglycerol Diacylglycerol(14:1/24:1) Diacylglycerol(14:1n5/24:1n9) Diacylglycerol(14:1W5/24:1W9) Diacylglycerol(38:2) Diglyceride 1-(9Z-Tetradecenoyl)-2-(15Z-tetracosanoyl)-sn-glycerol DG(14:1(9Z)/24:1(15Z)/0:0) C41H76O5 649.0391 648.569275542 (2S)-1-hydroxy-3-[(9Z)-tetradec-9-enoyloxy]propan-2-yl (15Z)-tetracos-15-enoate diacylglycerol [H][C@](CO)(COC(=O)CCCCCCC\C=C/CCCC)OC(=O)CCCCCCCCCCCCC\C=C/CCCCCCCC InChI=1S/C41H76O5/c1-3-5-7-9-11-13-15-16-17-18-19-20-21-22-23-24-26-28-30-32-34-36-41(44)46-39(37-42)38-45-40(43)35-33-31-29-27-25-14-12-10-8-6-4-2/h10,12,16-17,39,42H,3-9,11,13-15,18-38H2,1-2H3/b12-10-,17-16-/t39-/m0/s1 HVGPRJUMMPTUIX-NGOVACPCSA-N belongs to the class of organic compounds known as 1,2-diacylglycerols. These are diacylglycerols containing a glycerol acylated at positions 1 and 2. Organic compounds Lipids and lipid-like molecules Glycerolipids Diradylglycerols 1,2-diacylglycerols Carbonyl compounds Carboxylic acid esters Dicarboxylic acids and derivatives Fatty acid esters Hydrocarbon derivatives Organic oxides Primary alcohols 1,2-acyl-sn-glycerol Alcohol Aliphatic acyclic compound Carbonyl group Carboxylic acid derivative Carboxylic acid ester Dicarboxylic acid or derivatives Fatty acid ester Fatty acyl Hydrocarbon derivative Organic oxide Organic oxygen compound Organooxygen compound Primary alcohol Aliphatic acyclic compounds Solid logp 10.48 ALOGPS logs -7.76 ALOGPS logp 13.95 ChemAxon pka_strongest_acidic 14.58 ChemAxon pka_strongest_basic -3 ChemAxon iupac (2S)-1-hydroxy-3-[(9Z)-tetradec-9-enoyloxy]propan-2-yl (15Z)-tetracos-15-enoate ChemAxon average_mass 649.0391 ChemAxon mono_mass 648.569275542 ChemAxon smiles [H][C@](CO)(COC(=O)CCCCCCC\C=C/CCCC)OC(=O)CCCCCCCCCCCCC\C=C/CCCCCCCC ChemAxon formula C41H76O5 ChemAxon inchi InChI=1S/C41H76O5/c1-3-5-7-9-11-13-15-16-17-18-19-20-21-22-23-24-26-28-30-32-34-36-41(44)46-39(37-42)38-45-40(43)35-33-31-29-27-25-14-12-10-8-6-4-2/h10,12,16-17,39,42H,3-9,11,13-15,18-38H2,1-2H3/b12-10-,17-16-/t39-/m0/s1 ChemAxon inchikey HVGPRJUMMPTUIX-NGOVACPCSA-N ChemAxon polar_surface_area 72.83 ChemAxon refractivity 197.54 ChemAxon polarizability 85.13 ChemAxon rotatable_bond_count 38 ChemAxon acceptor_count 3 ChemAxon donor_count 1 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon number_of_rings 0 ChemAxon bioavailability 0 ChemAxon rule_of_five Yes ChemAxon ghose_filter Yes ChemAxon veber_rule Yes ChemAxon mddr_like_rule Yes ChemAxon De Novo Triacylglycerol Biosynthesis TG(14:1(9Z)/24:1(15Z)/24:1(15Z)) SMP0073492 Phosphatidylcholine Biosynthesis PC(14:1(9Z)/24:1(15Z)) SMP0080486 Phosphatidylethanolamine Biosynthesis PE(14:1(9Z)/24:1(15Z)) SMP0082289 Specdb::CMs 640413 Specdb::CMs 640414 Specdb::CMs 793759 Specdb::MsMs 626326 Specdb::MsMs 626327 Specdb::MsMs 626328 Specdb::MsMs 2503202 Specdb::MsMs 2503203 Specdb::MsMs 2503204 Specdb::MsMs 3044314 Specdb::MsMs 3044315 Specdb::MsMs 3044316 Specdb::MsMs 3098764 Specdb::MsMs 3098765 Specdb::MsMs 3098766 Specdb::MsMs 3112028 Specdb::MsMs 3112029 Specdb::MsMs 3112030 All Tissues Wishart DS, Feunang YD, Marcu A, Guo AC, Liang K, Vazquez-Fresno R, Sajed T, Johnson D, Li C, Karu N, Sayeeda Z, Lo E, Assempour N, Berjanskii M, Singhal S, Arndt D, Liang Y, Badran H, Grant J, Serra-Cayuela A, Liu Y, Mandal R, Neveu V, Pon A, Knox C, Wilson M, Manach C, Scalbert A: HMDB 4.0: the human metabolome database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D608-D617. doi: 10.1093/nar/gkx1089. 29140435 FDB024259 24765899 53478000 88709 BMDBP00391 Ethanolaminephosphotransferase 1 Q17QM4 SELENOI Enzyme