1.0 2018-05-07 22:20:28 UTC 2020-05-20 21:07:47 UTC BMDBP00024 BMDBP03084 Enzyme PTGIS Secondary metabolites biosynthesis, transport and catabolism Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2). BMDB0000692 Iron BMDB0001335 Prostaglandin I2 BMDB0001381 Prostaglandin H2 BMDB0003178 Heme BMDB0001993 7a-Hydroxy-cholestene-3-one BMDB0000221 NADPH BMDB0001377 Oxygen BMDB0002197 7a,12a-Dihydroxy-cholestene-3-one BMDB0000217 NADP BMDB0002111 Water BMDB0000067 Cholesterol BMDB0002103 27-Hydroxycholesterol BMDB0006281 7-a,27-dihydroxycholesterol BMDB0109593 3beta-Hydroxy-5-cholestenoic acid BMDB0012454 3 beta,7 alpha-Dihydroxy-5-cholestenoate 13 >1503 bp ATGTCCTGGGCCGTGGTCTTCGGCCTCCTGGCCGCGCTGCTGCTGCTGCTGCTGCTGACC CGCCGCCGCACGCGGCGACCTGGCGAGCCTCCCCTGGACCTGGGCAGTATCCCCTGGCTG GGTCACGCCTTGGAGTTTGGAAAAGATGCTGCCGGCTTCCTCACTAGGATGAAGGAGAAG CATGGGGACATCTTTACTGTGCTGGTGGGCGGCAGGCACGTCACGGTCCTCCTGGATCCC CACTCCTACGACGCGGTGGTGTGGGAGCCCCGCAGCAGGCTGGACTTCCACGCCTACGCC GTCTTCCTCATGGAGAGGATTTTCGACGTGCAGCTTCCGCATTATAACCCCGGTGATGAA AAGTCCAAGATGAAACCGACTCTCCTCCACAAAGAGCTGCAGGCGCTCACGGATGCCATG TATACCAACCTCCGCACTGTCCTGCTGGGTGACACCGTGGAAGCGGGCAGTGGCTGGCAC GAAATGGGGCTCCTCGAGTTCTCCTACGGCTTCCTGCTCAGAGCCGGCTACCTGACCCAG TACGGCGTTGAGGCACCGCCACACACCCAGGAGAGCCAGGCCCAGGACCGTGTCCACTCA GCCGACGTCTTCCACACCTTCCGCCAGCTTGACCTGCTGCTCCCCAAGCTGGCACGTGGC TCCCTGTCAGCGGGGGATAAGGACCGGGTGGGCAAGGTCAAAGGTCGCCTGTGGAAGCTG TTGTCCCCAACCAGGCTGGCCAGCCGGGCCCACCGGAGCAGATGGCTGGAGAGTTACCTG CTGCACCTGGAGGAGATGGGCGTGTCGGAGGAGATGCAGGCTCGCGCCCTGGTGCTGCAG CTCTGGGCCACACAGGGGAACATGGGTCCTGCTGCCTTCTGGCTCCTGCTCTTTCTCCTC AAGAACCCCGAGGCCCTGGCCGCTGTCCGTGGAGAGCTAGAGACTGTCCTTTTGGGAGCA GAGCAGCCCATATCACAGATGACCACCCTCCCACAGAAAGTTTTGGACAGCATGCCTGTG CTGGACAGCGTGCTGAGTGAGAGCCTCAGGCTCACCGCCGCGCCCTTCATCACCCGCGAG GTCGTGGCCGACCTGGCCTTGCCCATGGCGGATGGGCGGGAATTCAGCCTGCGACGTGGG GACCGCCTCCTCCTCTTTCCCTTCCTGAGTCCCCAGAAGGACCCGGAGATCTACACAGAC CCGGAGGTATTTAAATACAACCGATTCCTGAACCCTGATGGATCAGAGAAGAAAGACTTT TACAAAGATGGGAAGCGACTGAAGAACTACAGCTTGCCGTGGGGAGCAGGGCATAACCAG TGCCTGGGGAAGGGTTACGCCGTCAACAGCATCAAACAATTCGTGTTCCTTGTGCTGACG CAGTTTGACCTGGAGCTGATCACCCCGGACGTGGACATCCCCGAGTTTGACCTCAGCAGG TATGGCTTTGGGCTGATGCAGCCGGAACACGATGTGCCTGTCCGTTACCGCATCCGGCCG TGA 500 56629.0 7.29 1-20 None >Prostacyclin synthase MSWAVVFGLLAALLLLLLLTRRRTRRPGEPPLDLGSIPWLGHALEFGKDAAGFLTRMKEK HGDIFTVLVGGRHVTVLLDPHSYDAVVWEPRSRLDFHAYAVFLMERIFDVQLPHYNPGDE KSKMKPTLLHKELQALTDAMYTNLRTVLLGDTVEAGSGWHEMGLLEFSYGFLLRAGYLTQ YGVEAPPHTQESQAQDRVHSADVFHTFRQLDLLLPKLARGSLSAGDKDRVGKVKGRLWKL LSPTRLASRAHRSRWLESYLLHLEEMGVSEEMQARALVLQLWATQGNMGPAAFWLLLFLL KNPEALAAVRGELETVLLGAEQPISQMTTLPQKVLDSMPVLDSVLSESLRLTAAPFITRE VVADLALPMADGREFSLRRGDRLLLFPFLSPQKDPEIYTDPEVFKYNRFLNPDGSEKKDF YKDGKRLKNYSLPWGAGHNQCLGKGYAVNSIKQFVFLVLTQFDLELITPDVDIPEFDLSR YGFGLMQPEHDVPVRYRIRP BAA06383.1 Q29626 PTGIS_BOVIN D30718 PTGIS