1.0 2018-05-07 22:20:38 UTC 2020-05-20 21:04:13 UTC BMDBP00060 Enzyme CYP21 Secondary metabolites biosynthesis, transport and catabolism Specifically catalyzes the 21-hydroxylation of steroids. Required for the adrenal synthesis of mineralocorticoids and glucocorticoids. Steroidogenesis SMP0087238 BMDB0000692 Iron BMDB0003178 Heme BMDB0004031 11b-Hydroxyprogesterone BMDB0001377 Oxygen BMDB0001547 Corticosterone BMDB0002111 Water BMDB0004030 21-Deoxycortisol BMDB0000063 Cortisol BMDB0001830 Progesterone BMDB0000016 Deoxycorticosterone BMDB0000374 17-Hydroxyprogesterone BMDB0000015 Cortexolone 23 >1491 bp CCTCTGCCTGGGTCTCCAGCCATGGTCCTCGCAGGGCTGCTGCTGCTGCTGACCCTGCTC AGTGGCGCTCACCTGCTATGGGGCCGGTGGAAGCTCAGAAACCTCCACCTCCCACCTCTG GTCCCCGGCTTCCTGCACCTGCTGCAGCCCAACCTCCCCATCCATCTGCTGAGCCTGACT CAGAAACTCGGGCCTGTCTACAGGCTTCGCCTTGGGCTGCAAGAGGTGGTGGTGCTGAAC TCCAAGAGGACCATTGAGGAGGCTATGATCAGGAAGTGGGTGGACTTTGCCGGCAGACCC CAGATACCATCCTACAAGTTGGTGTCTCAGCGCTGCCAGGACATCTCTCTGGGGGACTAC TCTCTGCTCTGGAAGGCCCACAAGAAACTCACCCGCTCAGCCTTGCTGCTGGGCACCCGC AGCTCCATGGAGCCCTGGGTGGACCAGCTGACCCAGGAGTTCTGCGAGCGCATGAGAGTC CAGGCCGGTGCCCCCGTGACCATCCAGAAGGAATTCTCTCTGCTTACCTGCAGCATCATC TGTTACCTCACTTTTGGAAACAAGGAGGACACCTTAGTACATGCCTTTCACGACTGTGTT CAGGACTTGATGAAGACCTGGGACCACTGGTCCATCCAGATTTTGGACATGGTTCCTTTT CTCAGGTTCTTCCCCAACCCTGGGCTCTGGAGGCTGAAGCAGGCCATAGAGAACAGGGAC CACATGGTGGAGAAGCAGCTGACGCGCCACAAGGAGAGCATGGTGGCCGGCCAGTGGAGG GATATGACGGACTACATGCTCCAGGGGGTAGGGAGGCAAAGAGTAGAAGAGGGCCCCGGA CAGCTCCTGGAAGGACACGTGCACATGTCTGTGGTGGACCTTTTCATCGGGGGCACTGAA ACCACGGCGAGCACCCTCTCCTGGGCTGTGGCGTTCCTACTTCACCACCCCGAGATTCAG CGCCGCCTTCAGGAGGAGTTGGATCGCGAGCTGGGCCCCGGAGCCTCATGCTCCCGAGTC ACTTACAAGGACCGCGCTCGGCTGCCTCTGCTCAACGCCACCATCGCGGAGGTGCTGCGC CTGCGGCCGGTCGTGCCCCTGGCCTTGCCTCACCGCACCACGCGGCCTAGCAGCATCTTC GGCTACGACATCCCTGAGGGCATGGTCGTTATCCCCAACCTCCAAGGTGCCCACCTGGAC GAGACCGTCTGGGAGCAGCCGTACGAGTTCCGGCCGGACCGCTTCCTGGAGCCGGGCGCG AACCCCAGCGCGCTGGCATTTGGCTGCGGGGCGCGCGTGTGCCTGGGCGAGTCGCTGGCG CGCCTGGAGCTGTTCGTGGTGCTCCTGCGACTGCTGCAGGCCTTCACGCTGCTGCCGCCG CCCGTGGGCGCCCTGCCGTCGCTGCAGCCGGATCCCTACTGCGGTGTCAACCTCAAGGTC CAGCCTTTCCAGGTGCGGCTGCAGCCCCGGGGGGTGGAGGCCGGGGCCTGG 496 56077.0 8.34 None >Steroid 21-hydroxylase MVLAGLLLLLTLLAGAHLLWGRWKLRNLHLPPLVPGFLHLLQPNLPIHLLSLTQKLGPVY RLRLGLQEVVVLNSKRTIEEAMIRKWVDFAGRPQIPSYKLVSQRCQDISLGDYSLLWKAH KKLTRSALLLGTRSSMEPWVDQLTQEFCERMRVQAGAPVTIQKEFSLLTCSIICYLTFGN KEDTLVHAFHDCVQDLMKTWDHWSIQILDMVPFLRFFPNPGLWRLKQAIENRDHMVEKQL TRHKESMVAGQWRDMTDYMLQGVGRQRVEEGPGQLLEGHVHMSVVDLFIGGTETTASTLS WAVAFLLHHPEIQRRLQEELDRELGPGASCSRVTYKDRARLPLLNATIAEVLRLRPVVPL ALPHRTTRPSSIFGYDIPEGMVVIPNLQGAHLDETVWEQPHEFRPDRFLEPGANPSALAF GCGARVCLGESLARLELFVVLLRLLQAFTLLPPPVGALPSLQPDPYCGVNLKVQPFQVRL QPRGVEAGAWESASAQ AAA83247.1 P00191 CP21A_BOVIN 3QZ1 3QZ1 M11267 CYP21