1.0 2018-05-07 22:21:14 UTC 2020-05-20 21:04:20 UTC BMDBP00189 Enzyme ATP5F1B Energy production and conversion Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Subunits alpha and beta form the catalytic core in F(1). Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits. BMDB0001341 ADP BMDB0001362 Hydrogen BMDB0001429 Phosphate 5 >1587 bp ATGTTGGGACTTGTGGGTCGTGTGGTTGCTGCCTCGGCCTCCGGGGCCTTGCGGGGACTC AGCCCTTCAGCGCCGCTACCGCAAGCCCAGCTTTTACTGCGGGCCGCTCCTGCAGCGCTC CAGCCTGCCAGAGACTATGCCGCTCAAGCATCTCCATCGCCAAAGGCCGGCGCCACCACT GGGCGCATCGTGGCGGTCATTGGTGCAGTGGTGGACGTCCAGTTTGATGAGGGACTGCCT CCCATCCTAAATGCCCTGGAGGTGCAAGGCAGGGAGACCAGGCTGGTTTTGGAGGTGGCC CAGCATTTGGGTGAGAGCACAGTAAGGACCATTGCTATGGATGGTACAGAAGGCTTGGTT AGAGGTCAGAAAGTCCTGGATTCTGGTGCACCAATCAGAATTCCTGTTGGCCCTGAGACC TTGGGTAGAATCATGAACGTCATTGGAGAACCTATTGATGAGAGGGGTCCCATCAAAACC AAGCAATTTGCTGCTATTCATGCTGAGGCTCCTGAATTCGTGGAGATGAGTGTTGAACAA GAAATTCTGGTTACTGGTATTAAGGTTGTAGATCTGCTGGCTCCATATGCCAAGGGTGGC AAAATTGGGCTTTTTGGTGGTGCTGGAGTCGGCAAGACAGTACTGATCATGGAGTTAATC AACAATGTTGCCAAAGCCCATGGTGGTTACTCTGTGTTTGCTGGTGTTGGTGAAAGGACC CGTGAGGGCAATGACTTATACCATGAAATGATTGAGTCTGGTGTTATCAACTTAAAAGAT GCTACCTCTAAGGTAGCGCTGGTGTACGGTCAAATGAATGAACCACCTGGTGCTCGGGCC CGGGTTGCTCTGACTGGGCTGACTGTAGCTGAGTACTTCAGAGACCAAGAAGGTCAAGAT GTGTTGCTGTTTATTGATAACATCTTTCGCTTCACCCAGGCTGGCTCAGAGGTGTCTGCT TTATTGGGCAGAATCCCTTCTGCTGTGGGTTATCAGCCTACCCTGGCCACTGACATGGGT ACCATGCAGGAAAGAATCACCACCACCAAAAAGGGATCTATCACCTCTGTACAGGCTATC TATGTGCCTGCTGATGACTTGACGGATCCTGCCCCGGCCACTACCTTTGCCCATTTGGAT GCTACCACTGTGTTGTCCCGTGCTATTGCTGAGCTGGGCATCTATCCAGCTGTGGATCCT TTGGACTCCACGTCTCGCATCATGGATCCCAACATTGTTGGCAGTGAGCATTATGATGTT GCCCGTGGGGTGCAAAAGATTCTGCAGGACTACAAATCCCTCCAGGACATCATTGCTATC CTGGGTATGGATGAACTTTCTGAAGAAGATAAGTTAACTGTGTCTCGTGCACGGAAAATC CAGCGTTTCTTGTCTCAGCCATTCCAGGTGGCTGAGGTCTTTACTGGTCATTTGGGGAAG CTGGTACCCCTCAAGGAGACCATCAAAGGATTCCAGCAGATTTTGGCAGGTGAATATGAC CATCTCCCAGAACAGGCCTTCTATATGGTGGGACCCATTGAAGAAGCTGTGGCAAAAGCT GATAAGTTGGCTGAAGAGCACTCATGA 528 56284.0 4.92 None >ATP synthase subunit beta, mitochondrial MLGLVGRVVAASASGALRGLSPSAPLPQAQLLLRAAPAALQPARDYAAQASPSPKAGATT GRIVAVIGAVVDVQFDEGLPPILNALEVQGRETRLVLEVAQHLGESTVRTIAMDGTEGLV RGQKVLDSGAPIRIPVGPETLGRIMNVIGEPIDERGPIKTKQFAAIHAEAPEFVEMSVEQ EILVTGIKVVDLLAPYAKGGKIGLFGGAGVGKTVLIMELINNVAKAHGGYSVFAGVGERT REGNDLYHEMIESGVINLKDATSKVALVYGQMNEPPGARARVALTGLTVAEYFRDQEGQD VLLFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGTMQERITTTKKGSITSVQAI YVPADDLTDPAPATTFAHLDATTVLSRAIAELGIYPAVDPLDSTSRIMDPNIVGSEHYDV ARGVQKILQDYKSLQDIIAILGMDELSEEDKLTVSRARKIQRFLSQPFQVAEVFTGHLGK LVPLKETIKGFQQILAGEYDHLPEQAFYMVGPIEEAVAKADKLAEEHS AAA30395.1 P00829 ATPB_BOVIN 1BMF 1COW 1E1Q 1E1R 1E79 1EFR 1H8E 1H8H 1NBM 1OHH 1QO1 1W0J 1W0K 2CK3 2JDI 2JIZ 2JJ1 2JJ2 2V7Q 2W6E 2W6F 2W6G 2W6H 2W6I 2W6J 2WSS 2XND 4ASU 4TSF 4TT3 4YXW 4Z1M 5ARA 5ARE 5ARH 5ARI 5FIJ 5FIK 5FIL 1BMF 1COW 1E1Q 1E1R 1E79 1EFR 1H8E 1H8H 1NBM 1OHH 1W0J 1W0K 2CK3 2JDI 2JIZ 2JJ1 2JJ2 2V7Q 2W6E 2WSS 2XND 4ASU 4TSF 4TT3 4YXW 4Z1M M20929 ATP5F1B