1.0 2018-05-07 22:22:01 UTC 2020-05-20 21:52:37 UTC BMDBP00359 Enzyme HMGCS2 Lipid transport and metabolism This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (R)-mevalonate biosynthesis (R)-mevalonate from acetyl-CoA: step 2/3 Butyrate Metabolism SMP0087185 Ketone Body Metabolism SMP0087202 Metabolic intermediate biosynthesis Valine, Leucine, and Isoleucine Degradation SMP0087234 BMDB0001206 Acetyl-CoA BMDB0001375 3-Hydroxy-3-methylglutaryl-CoA BMDB0001484 Acetoacetyl-CoA BMDB0002111 Water BMDB0001423 Coenzyme A 3 >1527 bp ATGCAGCGGCTGTTGACTCCAGTGAGGCAGGTGTTGCAAGTGAAGAGAGTGATGCAAGAA GCTTCCCTCCTGCCTGCCCGCCTTCTCCCAGCAGCCCACCCCAGTTTTTCTACAGTTCCG GCTGTCCCCTTGGCCAAAACAGATACTTGGCCAAAGGATGTGGGTATTCTTGCCATGGAG GTCTACTTTCCAGCCCAATATGTGGACCAAACAGAGCTGGAGAAGTTTAACAAAGTGGAG GCAGGGAGGTACACCGTGGGCTTGGGCCAGACCCAGATGGGCTTCTGCTCAGTCCAGGAG GATGTCAACTCCCTGTGCCTGACGGTGGTGCAACAGCTGATGGAGCGCACGCAGCTCCCC TGGGACTCTGTGGGCCGCCTGGAAGTGGGCACTGAGACCATCATCGATAAGTCCAAGGCT GTCAAAACAGTGCTTATGGAGCTCTTCCAGGATTCAGGCAACACTGACATTGAGGGCATA GATACCACCAATGCCTGCTACGGTGGCACTGCCTCCCTCTTCAATGCTGCCAACTGGATG GAATCCAGCTCCTGGGATGGTCGCTATGCACTGGTGGTCTGTGGGGACATCGCAGTCTAC CCCAGTGGTAACGCTCGCCCCACAGGCGGGGCTGGAGCTGTGGCAATGCTGGTTGGGCCT GAGGCCCCTCTGGTCCTCGAGAGAGGGCTTAGAGGAACCCACATGGAGAATGTGTACGAC TTCTACAAACCAGATGTGACTTCAGAGTACCCACTGGTGGATGGGAAGCTCTCCATCCAG TGCTACTTACGGGCCCTGGACAAATGCTATGCATTCTACCGTCAAAAGATCGAGAAACAG TGGAAGCAAGCTGGCATCGATCGGCCTTTCACTCTCGATGATGTGCAGTATATGATTTTT CACACGCCTTTCTGCAAGTTAGTCCAGAAATCCCTGGCCCGCCTGATGTTCAATGACTTC CTGTTGGCCAGTGGTGACACACAGACTGGCATCTACAAGGGCTTGGAGGCCTTCAGGGGA CTAAAGCTGGAAGACACCTACACCAATAAGGATGTAGATAAAGCATTTCTAAAAGCCTCT CTGAACATGTTCAATAAGAAAACCAAGAACTCCCTCTACCTCTCCACGTACAACGGGAAT ATGTACACCTCATCCCTATATGGATGCCTGGCCTCACTTCTGGCCCATCACTCTGCCCAA GACTTGGCTGGCTCCAGGATCGGTGCCTTCTCTTATGGCTCTGGTTTGGCAGCAAGTTTC TTTTCTTTCCGGGTGTCCCAGGATGCTTCTCCAGGCTCCCCACTGGAGAAGCTGGTATCC AGTACATCAGACCTGCAGAAACGTCTTGCCTCCCGGAAGCGTGTGTCTCCTGAGGAGTTC ACAGAAATAATGAACCAAAGAGAACAATACTACCACAAGATGAATTTCTCACCACCTGGT GATAAGAACAGCCTTTTCCCAGGCACTTGGTACCTGGAGCGAGTGGATGAGCTGTATCGC AGGAAGTACGCCCGGCGTCCCGTTTAA 508 56895.0 8.16 34-54 84-105 117-134 140-160 172-191 245-266 272-294 362-386 406-432 453-472 484-502 586-604 None >Hydroxymethylglutaryl-CoA synthase, mitochondrial MQRLLTPVRQVLQVKRVMQEASLLPARLLPAAHPSFSTVPAVPLAKTDTWPKDVGILAME VYFPAQYVDQTELEKFNKVEAGRYTVGLGQTQMGFCSVQEDVNSLCLTVVQQLMERTQLP WDSVGRLEVGTETIIDKSKAVKTVLMELFQDSGNTDIEGIDTTNACYGGTASLFNAANWM ESSSWDGRYALVVCGDIAVYPSGNARPTGGAGAVAMLVGPEAPLVLERGLRGTHMENVYD FYKPDVTSEYPLVDGKLSIQCYLRALDKCYAFYRQKIEKQWKQAGIDRPFTLDDVQYMIF HTPFCKLVQKSLARLMFNDFLLASGDTQTGIYKGLEAFRGLKLEDTYTNKDVDKAFLKAS LNMFNKKTKNSLYLSTYNGNMYTSSLYGCLASLLAHHSAQDLAGSRIGAFSYGSGLAASF FSFRVSQDASPGSPLEKLVSSTSDLQKRLASRKRVSPEEFTEIMNQREQYYHKMNFSPPG DKNSLFPGTWYLERVDELYRRKYARRPV AAI12667.1 Q2KIE6 HMCS2_BOVIN BC112666 HMGCS2