1.0 2018-05-07 22:22:46 UTC 2020-05-20 21:05:32 UTC BMDBP00521 Enzyme IDH3A Energy production and conversion Catalytic subunit of the enzyme which catalyzes the decarboxylation of isocitrate (ICT) into alpha-ketoglutarate. The heterodimer composed of the alpha (IDH3A) and beta (IDH3B) subunits and the heterodimer composed of the alpha (IDH3A) and gamma (IDH3G) subunits, have considerable basal activity but the full activity of the heterotetramer (containing two subunits of IDH3A, one of IDH3B and one of IDH3G) requires the assembly and cooperative function of both heterodimers. Citric Acid Cycle SMP0087163 Warburg Effect SMP0087270 BMDB0000193 Isocitric acid BMDB0000208 Oxoglutaric acid BMDB0000547 Magnesium BMDB0000902 NAD BMDB0001333 Manganese BMDB0001487 NADH 21 >1101 bp ATGGCAGGGCCCGCGTGGATCTCCAAGGTCTCTCGGCTGCTGGGGGCATTCCACAACCAA AAACAGGTGACCAGAGGTTTTGCTGGTGGTGTTAAGACAGTAACTTTAATTCCAGGAGAT GGAATTGGCCCAGAAATTTCTGCTGCAGTTATGAAGATTTTTGATGCTGCCAAAGCACCT ATTCAGTGGGAGGAGCGAAACGTCGCCGCCATTCAAGGTCCGGGAGGCAAGTGGATGATC CCTCCAGAAGCCAAAGAGTCCATGGATAAGAACAAGATGGGCTTGAAAGGCCCTTTAAAA ACACCAATAGCTGCTGGTCACCCATCTATGAATTTATTGCTGCGTAAAACATTTGACCTT TATGCAAATGTCCGACCATGTGTCTCAATCGAAGGCTATAAAACCCCTTACCATGATGTA AATATTGTCACCATTCGAGAGAACACGGAAGGAGAATACAGTGGAATCGAGCATGTGATC GTGGATGGAGTTGTGCAGAGTATCAAGCTCATCACCGAGGCAGCGAGCAAGCGCATCGCG GAGTTTGCATTTGAATACGCACGGAACAACCACCGGAGCAACGTCACAGCCGTGCACAAA GCCAACATCATGCGAATGTCAGATGGGCTTTTTCTGCAAAAATGCAGGGAAGTTGCAGAA AACTGTAAAGATATTAAATTTAATGAGATGTACCTTGATACAGTATGTTTGAATATGGTC CAAGACCCGTCCCAGTTTGATGTTCTTGTTATGCCAAATTTGTATGGAGACATCCTTAGT GACCTGTGTGCGGGATTGATTGGAGGTCTTGGTGTGACACCAAGCGGCAACATTGGAGCC AACGGAGTTGCAATCTTCGAGTCGGTTCACGGGACCGCCCCGGACATTGCGGGCAAGGAC ATGGCCAATCCCACAGCCCTCCTGCTCAGCGCCGTGATGATGCTGCGCCACATGGGGCTT TTTGACCACGCTGCGAAGATTGAGACGGCGTGTTTTGCTACAATTAAGGATGGAAAGAGC TTAACCAAAGATTTGGGAGGCAATTCAAAGTGCTCGGACTTCACAGAAGAAATCTGTCGC CGAGTAAAAGATTTAGATTAA 366 39668.0 7.22 None >Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial MAGPAWISKVSRLLGAFHNQKQVTRGFAGGVKTVTLIPGDGIGPEISAAVMKIFDAAKAP IQWEERNVAAIQGPGGKWMIPPEAKESMDKNKMGLKGPLKTPIAAGHPSMNLLLRKTFDL YANVRPCVSIEGYKTPYHDVNIVTIRENTEGEYSGIEHVIVDGVVQSIKLITEAASKRIA EFAFEYARNNHRSNVTAVHKANIMRMSDGLFLQKCREVAENCKDIKFNEMYLDTVCLNMV QDPSQFDVLVMPNLYGDILSDLCAGLIGGLGVTPSGNIGANGVAIFESVHGTAPDIAGKD MANPTALLLSAVMMLRHMGLFDHAAKIETACFATIKDGKSLTKDLGGNSKCSDFTEEICR RVKDLD AAC18425.1 P41563 IDH3A_BOVIN U07980 IDH3A