1.0 2018-05-07 22:27:42 UTC 2020-05-20 21:52:40 UTC BMDBP01596 Enzyme RHOU Involved in GTP binding Acts upstream of PAK1 to regulate the actin cytoskeleton, adhesion turnover and increase cell migration. Stimulates quiescent cells to reenter the cell cycle. Has no detectable GTPase activity but its high intrinsic guanine nucleotide exchange activity suggests it is constitutively GTP-bound. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape (By similarity). BMDB0000547 Magnesium 28 >768 bp ATGCCCCCGCAGCAGGGGGACCCCGCGTTCCCGGGCCGCTGCGAGGCGCCGCCCGTGCCG CCCCGCCGGGAGCGCGGGGTCCGTGGGCCCGGGGCGCCGGGGGGCCGGGGGCGCGCGGGC GGCCCCGAGGGGCACGGCGTCAAGTGCGTGCTGGTCGGCGACGGCGCCGTGGGCAAGACC AGCTTGGTGGTGAGCTACACCACCAACGGCTACCCCACCGAGTACATCCCCACCGCCTTC GACAACTTCTCGGCTGTGGTTTCCGTGGATGGGCGGCCCGTGAAACTCCAGCTCTGTGAC ACTGCAGGACAGGATGAGTTTGACAAGCTCCGGCCTCTGTGCTACACCAATGCCGACATC TTCCTCCTGTGCTTCAGTGTTGTGGGTCCCTCCTCCTTCCAGAACGTCAGTGAGAAATGG GTGCCAGAGATTCGGTGCCACTGTCCCAAAGCCCCCATCATCCTCGTGGGGACACAGTCG GACCTCAGAGAAGACGTCAAAGTCCTCATCGAGCTGGACAAATGCAAAGAGAAGCCGGTA CCCGAGGAGGCGGCCAGGTTGTGTGCCGAGGAGATCAAAGCCACCTCTTACATTGAGTGC TCGGCCTTGACTCAGAAGAACCTCAAAGAGGTCTTCGATGCAGCCATTGTAGCCGGCATT CAGTATTCAGACTCCCAGCAGCAGCCAAAGAAGTCCAAGAGCAGGACTCCCGACAAGATG AAGACCTTATCCAAGTCCTGGTGGAAGAAGTACTGCTGTTTCGTATGA 255 27824.0 8.14 30-56 77-98 113-133 140-158 178-200 229-246 288-307 319-338 350-372 None >Rho-related GTP-binding protein RhoU MPPQQGDPAFPGRCEAPPVPPRRERGVRGPGAPGGRGRAGGPEGHGVKCVLVGDGAVGKT SLVVSYTTNGYPTEYIPTAFDNFSAVVSVDGRPVKLQLCDTAGQDEFDKLRPLCYTNADI FLLCFSVVGPSSFQNVSEKWVPEIRCHCPKAPIILVGTQSDLREDVKVLIELDKCKEKPV PEEAARLCAEEIKATSYIECSALTQKNLKEVFDAAIVAGIQYSDSQQQPKKSKSRTPDKM KTLSKSWWKKYCCFV AAI40581.1 A5D7J5 RHOU_BOVIN BC140580 RHOU