1.0 2018-05-07 22:32:16 UTC 2020-05-20 21:07:39 UTC BMDBP02586 Enzyme CNTN1 Involved in protein binding Contactins mediate cell surface interactions during nervous system development. Involved in the formation of paranodal axo-glial junctions in myelinated peripheral nerves and in the signaling between axons and myelinating glial cells via its association with CNTNAP1. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus. Interaction with TNR induces a repulsion of neurons and an inhibition of neurite outgrowth (By similarity). BMDB0000158 L-Tyrosine 5 >3057 bp ATGAAAATGTGGTTACTGTTCAGTCTCCTTGTAATAATATCTTTTAAAACTTGTCTATCA GAGTTTACATGGCACAGAAGGTATGGTCATGGAGTTTCTGAGGAAGACAAAGGATTTGGA CCAATTTTTGAAGAACAACCAATCAATACCATTTATCCAGAGGAGTCACCGGAAGGAAAA GTTTCACTAAACTGTAGGGCACGAGCCAGCCCTTTCCCAGTTTACAAATGGAGAATGAAT AATGGGGATATTGATCTGACAAGTGATCGGTACAGTATGGTAGGAGGAAACCTTGTTATC AACAATCCGGACAAACAGAAAGATGCTGGAATATATTACTGTTTAGCATCAAATAACTAT GGGATGGTCAGAAGCACTGAAGCAACCCTGAGTTTTGGATATCTTGATCCTTTCCCACCT GAGGAACGTCCTGAGGTCAGAGTGAAAGAAGGGAAGGGAATGGTGCTACTCTGTGACCCT CCATACCATTTCCCAGATGATCTTAGCTACCGCTGGCTTCTAAATGAATTTCCTGTATTT ATCACAATGGATAAACGAAGATTTGTGTCTCAGACAAATGGCAATCTCTACATTGCTAAT GTTGAGGCATCTGACAAAGGCAACTATTCTTGCTTTGTATCCAGTCCCTCTATTACAAAG AGTGTGTTCAGCAAATTTATCCCACTCATTCCACTACCTGAACGAACAACAAAACCATAT CCTGCTGATATTGTAGTTCAGTTCAAGGATGTATATGCATTGATGGGCCAAAACGTGACT TTAGAGTGTTTTGCACTTGGCAATCCTGTTCCTGATATCCGATGGCGAAAAGTCCTAGAA CCAATGCCAAGCACAGCTGAGATCAGCACCTCTGGAGCTGTCCTCAAGATCTTCAATATT CAGCTAGAAGATGAAGGCATATATGAATGCGAGGCTGAGAACAATAGAGGAAAGGATAAA CACCAGGCAAGAATTTATGTTCAAGCATTTCCTGAGTGGGTGGAACACATCAATGACACA GAAGTGGATATAGGCAGTGATCTCTACTGGCCTTGTGTGGCCACGGGGAAGCCCATTCCT ACCATCCGATGGCTGAAGAATGGATATTCGTACCATAGAGGGGAACTGAGGCTGTATGAC GTGACCTTTGAAAACGCTGGCATGTACCAGTGCATAGCTGAAAACACACATGGAGCAATT TACGCAAATGCCGAGTTGAAGATCCTGGCTTTGGCTCCAACTTTTGAAATGAATCCTATG AAGAAAAAGATCCTGGCTGCTAAAGGAGGACGGGTTATAATTGAATGCAAACCCAAAGCT GCACCCAAACCAACATTTTTATGGAGTAAAGGCACAGAGCGGCTTGTCAATAGCAGCAGA ATACTCATTTGGGAAGATGGTAGCTTAGAAATCAATAACATTACAAGGAGTGATGGAGGT GTCTATACATGCTTTGTGGAAAATAATAAAGGGAAGGCTAATAGCACTGGGACTCTTGTT ATCACAGATCCCACACGAATTATCTTGGCCCCGATTAACGCTGATATCACTGTTGGAGAA AATGCCACCATGCAGTGTGCCGCTTCCTTTGATCCTGCCCTGGATCTGACATTTGTTTGG TCCTTCAATGGTTATGTGATCGACTTTAACAAAGAGAACATTCATTACCAGCGGAATTTT ATGCTGGATTCCAATGGGGAGCTGCTCATCCGAAATGCCCAGTTGAAACACGCTGGGAGG TACACGTGCACAGCTCAGACAATTGTAGACAATTCTTCAGCCTCTGCTGACCTTGTTGTG CGAGGCCCTCCAGGCCCTCCAGGTGGTCTGCGAATAGAAGACATTAGAGCCACTTCGGTG GCACTTACTTGGAGCCGTGGTTCAGACAATCATAGTCCTATATCTAAGTACACTATCCAG ACGAAGACTATTCTTTCGGATGATTGGAAAGATGCGAAGACAGATCCCCCAATTATTGAA GGAAACATGGAGGCAGCGAGAGCAGTGGATTTAATCCCATGGATGGAATATGAATTTCGT GTGGTAGCAACCAATACATTGGGTATAGGAGAGCCCAGTATACCATCAAACAAAATTAAA ACAGATGGCGCTGCACCTAATGTGGCTCCTTCAGATGTAGGAGGTGGAGGTGGAAGCAAC AGAGAACTGACCATAACATGGGCGCCTTTGTCAAGAGAATACCATTACTTCAACAATTTT GGTTACATAGTGGCATTTAAGCCATTTGATGGGGAAGAATGGAAAAAAGTGACAGTTACT AATCCAGATACTGGCCGCTATGTCCATAAAGACGAGACCATGCGCCCTTCCACTGCATTT CAAGTCAAAGTCAAAGCTTTCAACAACAAAGGAGACGGACCCTACAGTCTCACAGCTGTC ATCCACTCCGCACAAGACGCTCCCAGTGAAGCCCCAACAGCAGTAGGAGTAAAAGTCTTA TCATCTTCTGAGATATCTGTTCATTGGGAGCATGTTGTAGAAAAAATAGTAGAAAGCTAT CAGATTCGGTACTGGGCTTCCCATGACAAAGAAGCAGCTGCACACAGAGTTCAAGTTGCT AGCCAAGAATACTCGGCCAGGCTGGAGAACCTTCTGCCTGACACCCAGTATTTTGTGGAA GTCAGGGCGTGCAATAGTGCAGGGTGTGGACCTCCCAGTGATATGACTGAGACCTTCACC AAGAAAGCACCTCCAAGCCAGCCTCCGCGGATCATCAGTTCCGTAAGGTCTGGTTCACGC TACATAATCACCTGGGATCATGTGGTTGCACTGTCAAATGAATCTACAGTGACGGGATAT AAGGTACTCTATAGACCTGATGGCCAGCATGATGGCAAGCTGTATTCAACTCATAAACAC TCCATAGAAGTCCCAATCCCCAGGGATGGAGAATATGTTGTAGAGGTTCGTGCACACAGT GATGGAGGAGATGGAGTGGTGTCTCAAGTCAAAATTTCAGGTGCATCCATCCTATCACCA TGTCTTCTCGGCTTCCTGCTGCCTGCCCTTGGCATCCTTGTCTACTTGGAATTCTGA 1018 113385.0 6.15 1-20 >Contactin-1 MKMWLLFSLLVIISFKTCLSEFTWHRRYGHGVSEEDKGFGPIFEEQPINTIYPEESPEGK VSLNCRARASPFPVYKWRMNNGDIDLTSDRYSMVGGNLVINNPDKQKDAGIYYCLASNNY GMVRSTEATLSFGYLDPFPPEERPEVRVKEGKGMVLLCDPPYHFPDDLSYRWLLNEFPVF ITMDKRRFVSQTNGNLYIANVEASDKGNYSCFVSSPSITKSVFSKFIPLIPLPERTTKPY PADIVVQFKDVYALMGQNVTLECFALGNPVPDIRWRKVLEPMPSTAEISTSGAVLKIFNI QLEDEGIYECEAENNRGKDKHQARIYVQAFPEWVEHINDTEVDIGSDLYWPCVATGKPIP TIRWLKNGYSYHRGELRLYDVTFENAGMYQCIAENTHGAIYANAELKILALAPTFEMNPM KKKILAAKGGRVIIECKPKAAPKPTFLWSKGTERLVNSSRILIWEDGSLEINNITRSDGG VYTCFVENNKGKANSTGTLVITDPTRIILAPINADITVGENATMQCAASFDPALDLTFVW SFNGYVIDFNKENIHYQRNFMLDSNGELLIRNAQLKHAGRYTCTAQTIVDNSSASADLVV RGPPGPPGGLRIEDIRATSVALTWSRGSDNHSPISKYTIQTKTILSDDWKDAKTDPPIIE GNMEAARAVDLIPWMEYEFRVVATNTLGIGEPSIPSNKIKTDGAAPNVAPSDVGGGGGSN RELTITWAPLSREYHYFNNFGYIVAFKPFDGEEWKKVTVTNPDTGRYVHKDETMRPSTAF QVKVKAFNNKGDGPYSLTAVIHSAQDAPSEAPTAVGVKVLSSSEISVHWEHVVEKIVESY QIRYWASHDKEAAAHRVQVASQEYSARLENLLPDTQYFVEVRACNSAGCGPPSDMTETFT KKAPPSQPPRIISSVRSGSRYIITWDHVVALSNESTVTGYKVLYRPDGQHDGKLYSTHKH SIEVPIPRDGEYVVEVRAHSDGGDGVVSQVKISGASILSPCLLGFLLPALGILVYLEF BAA06861.1 Q28106 CNTN1_BOVIN D32135 CNTN1