1.0 2018-05-07 22:32:18 UTC 2020-05-20 21:02:57 UTC BMDBP02594 Enzyme GTF2I Interacts with the basal transcription machinery by coordinating the formation of a multiprotein complex at the C-FOS promoter, and linking specific signal responsive activator complexes. Promotes the formation of stable high-order complexes of SRF and PHOX1 and interacts cooperatively with PHOX1 to promote serum-inducible transcription of a reporter gene deriven by the C-FOS serum response element (SRE). Acts as a coregulator for USF1 by binding independently two promoter elements, a pyrimidine-rich initiator (Inr) and an upstream E-box. Required for the formation of functional ARID3A DNA-binding complexes and for activation of immunoglobulin heavy-chain transcription upon B-lymphocyte activation (By similarity). BMDB0000158 L-Tyrosine 25 >2937 bp ATGGCCCAAGTAGCAGTGTCTACCCTGCCTGTCGAAGACGAGGAGTCCTCAGAGAGCAGG ATGGTGGTGACGTTCCTCATGTCTGCTCTTGAGTCCATGTGTAAAGAACTGGCCAAGTCC AAGGCGGAAGTAGCGTGCATCGCAGTGTATGAGACAGACGTGTTTGTTGTTGGAACCGAG AGAGGACGTGCTTTTGTCAACACTAGAAAGGACTTTCAGAAAGATTTTGTAAAATACTGT GTTGAAGAAGAAGAAAAGGCTGCAGAGATGCATAAAATGAAATCTACAGCCCAGGCAAAT CGGATGAGTGTCGATGCTGTGGAGATAGAAACACTCAGAAAAACAGTTGAGGACTATTTC TGCTTTTGCTATGGGAAAGCTTTAGGCAAGTCAACAGTGGTGCCTGTTCCATATGAAAAG ATGCTCCGAGATCAGTCGGCCGTGGTGGTGCAGGGGCTTCCAGAAGGAGTAGCCTTCAAA CACCCTGAAAACTATGATCTTGCAACCCTGAAGTGGATTTTGGAGAACAAAGCAGGGATT TCATTTATCATTAAAAGACCTTTCCTAGAGCCAAAGAAGCACCTAGGTGGTCGTGTGATG GTTACAGATGCTGAAAGGTCAATGATATCTCCAAGTGGAAGCTGTGGCCCCGTCAAAGTA AAAACAGAACCCTCAGAGGATTCTGGCATTTCTCTGGAAATGGCAGCTGTGACAGTGAAG GAAGAATCTGAAGATCCTGATTACTATCAATATAACATTCAAGCAGGCCCTTCTGAAACT GATGATGTTGATGACAAACTCCCCCTTTCGAAGTCTTTGCAAGGAAGCCATCATTCTTCA GAGGGCAATGAAGGAACAGAAATGGAAGTACCAGCAGAAGATGATGACTATCCTCCACCT GCCAAGAGACCAAAGAGCAGTGAACCTCCCCAGCCACCCGTCACAGAACCTGCGAATGCC GGCAAACGGAAAGTGAGGGAGTTCAACTTCGAGAAATGGAATGCTCGAATTACTGATCTG CGTAAACAAGTTGAAGAGTTGTTTGAAAGAAAGTATGCTCAAGCTATAAAAGCCAAAGGT CCTGTGACGATCCCGTACCCTCTTTTCCAGTCCCATGTGGAAGATCTTTATGTAGAAGGA CTTCCAGAAGGAATCCCCTTTAGAAGGCCATCAACTTATGGAATCCCTCGCCTTGAGAGG ATATTACTTGCAAAGGAAAGGATTCGTTTTGTGATTAAGAAGCATGAACTTTTGAATTCA ACACGTGAAGACTTACAGCTTGATAAACCAGCTTCAGGAGTCAAGGAAGAGTGGTATGCC AGAATCACTAAGTTACGAAAGATGGTAGATCAGCTTTTCTGTAAAAAATTTGCTGAAGCC TTAGGGAGCACCGAAGCTAAGGCTGTACCTTACCAGAAATTTGAAGCACACCCTAATGAC CTCTACGTGGAAGGACTGCCAGAAAACATTCCTTTTAGAAGTCCCTCGTGGTATGGGATC CCAAGGCTGGAAAAGATTATTCAAGTGGGCAATCGAATTAAATTTGTTATTAAAAGACCA GAGCTTCTGACGCACAGCACTACTGAAGTTACTCAGCCCAGAACGAATACACCAGTCAAA GAAGATTGGAATGTCAGAATTACCAAGCTACGGAAGCAAGTGGAAGAGATTTTTAATTTG AAATTTGCTCAAGCTCTTGGACTCACAGAAGCAGTAAAAGTACCATACCCGGTGTTTGAA TCAAACCCCGAGTTCCTCTATGTAGAAGGCTTGCCAGAAGGAATTCCCTTTCGAAGCCCT ACCTGGTTTGGAATTCCAAGACTGGAAAGGATTGTCCGTGGAAGTAATAAAATCAAGTTT GTTGTTAAAAAACCTGAACTAGTTATTTCCTACTTGCCTCCTGGAATGGCTAGTAAAATA AACACTAAAGCTTTGCAGTCCCCGAAAAGACCACGAAGCCCCGGGAGTAATTCGAAAGTT CCTGAAATTGAGGTCACTGTGGAAGGCCCTAATAATAGCAATCCTCAAACCTCAGCCGTT CGAACCCCTACCCAGACGAATGGTTCTAATGTTCCCTTCAAGCCTCGAGGGAGAGAGTTT TCCTTTGAGGCCTGGAATGCCAAAATCACAGACCTAAAACAGAAAGTTGAAAATCTTTTC AATGAAAAATGTGGTGAAGCTCTTGGCCTTAAACAAGCTGTGAAAGTGCCGTTCGCGTTA TTTGAGTCTTTCCCAGAAGACTTTTATGTGGAAGGCTTACCCGAGGGTGTGCCATTCCGA CGACCGTCTACTTTTGGCATTCCAAGGCTGGAGAAGATACTCAGAAACAAAGCCAAAATT AAGTTCATCATTAAAAAGCCAGAAATGTTTGAGACTGCAATTAAGGAGAGCACCTCCTCA TCTAAGAGCCCTCCAAGAAAAATCAATTCATCACCCAGTGTTAATACTACTGCATCAGGT GTTGAAGACCTTAACATCATTCAGGTGACAATTCCAGACGATGATAATGAAAGACTATCA AAAGTTGAAAAAGCTCGACAGCTAAGAGAGCAAGTTAATGACCTCTTCAGTCGAAAATTT GGTGAAGCCATTGGGATGGGTTTCCCCGTGAAGGTTCCTTACAGGAAAATCACAATTAAC CCTGGCTGTGTGGTGGTTGATGGCATGCCCCCCGGAGTGTCATTCAAAGCCCCCAGCTAT CTGGAAATCAGCTCCATGAGAAGGATCTTAGATTCTGCTGAGTTCATTAAATTCACAGTC ATTAGACCATTTCCAGGACTTGTGATTAATAACCAGTTGGTTGATCAGAATGAGTCAGAA GGCCCAGTGATCCAAGAATCAGCTGAGCCAACCCAGTTGGAGGTTCCTGCAACCGAAGAA ATAAAGGAGACTGATGGAAACTCCCAAATCAAGCAAGAACCAGACCCTACGTGGTAG 978 110125.0 7.47 None >General transcription factor II-I MAQVAVSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTE RGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTAQANRMSVDAVEIETLRKTVEDYF CFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGI SFIIKRPFLEPKKHLGGRVMVTDAERSMISPSGSCGPVKVKTEPSEDSGISLEMAAVTVK EESEDPDYYQYNIQAGPSETDDVDDKLPLSKSLQGSHHSSEGNEGTEMEVPAEDDDYPPP AKRPKSSEPPQPPVTEPANAGKRKVREFNFEKWNARITDLRKQVEELFERKYAQAIKAKG PVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIKKHELLNS TREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAEALGSTEAKAVPYQKFEAHPND LYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKRPELLTHSTTEVTQPRTNTPVK EDWNVRITKLRKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSP TWFGIPRLERIVRGSNKIKFVVKKPELVISYLPPGMASKINTKALQSPKRPRSPGSNSKV PEIEVTVEGPNNSNPQTSAVRTPTQTNGSNVPFKPRGREFSFEAWNAKITDLKQKVENLF NEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAKI KFIIKKPEMFETAIKESTSSSKSPPRKINSSPSVNTTASGVEDLNIIQVTIPDDDNERLS KVEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSY LEISSMRRILDSAEFIKFTVIRPFPGLVINNQLVDQNESEGPVIQESAEPTQLEVPATEE IKETDGNSQIKQEPDPTW AAI51388.1 A7MB80 GTF2I_BOVIN 1Q60 BC151387 GTF2I