You are using an unsupported browser. Please upgrade your browser to a newer version to get the best experience on Bovine Metabolome Database.
Record Information |
---|
Version | 1.0 |
---|
Creation Date | 2016-09-30 22:33:50 UTC |
---|
Update Date | 2020-06-04 20:38:12 UTC |
---|
BMDB ID | BMDB0000628 |
---|
Secondary Accession Numbers | |
---|
Metabolite Identification |
---|
Common Name | Epitestosterone |
---|
Description | Testosterone belongs to the class of organic compounds known as androgens and derivatives. These are 3-hydroxylated C19 steroid hormones. They are known to favor the development of masculine characteristics. They also show profound effects on scalp and body hair in humans. Thus, testosterone is considered to be a steroid lipid molecule. Testosterone exists as a solid, very hydrophobic, practically insoluble (in water), and relatively neutral molecule. Testosterone exists in all living organisms, ranging from bacteria to humans. Testosterone participates in a number of enzymatic reactions, within cattle. In particular, Testosterone can be converted into 19-hydroxytestosterone; which is catalyzed by the enzyme cytochrome P450 19A1. In addition, Testosterone can be converted into androstenedione; which is catalyzed by the enzyme testosterone 17-beta-dehydrogenase 3. In cattle, testosterone is involved in the metabolic pathway called the androgen and estrogen metabolism pathway. Testosterone is a potentially toxic compound. |
---|
Structure | |
---|
Synonyms | Value | Source |
---|
Epi-testosterone | ChEBI | 17-Epitestosterone | HMDB | 17a-cis-Testosterone | HMDB | cis-Testosterone | HMDB | Isotestosterone | HMDB | 17-alpha-Testosterone | HMDB | 17 alpha Testosterone | HMDB | Epitestosterone | MeSH, HMDB |
|
---|
Chemical Formula | C19H28O2 |
---|
Average Molecular Weight | 288.4244 |
---|
Monoisotopic Molecular Weight | 288.20893014 |
---|
IUPAC Name | Not Available |
---|
Traditional Name | Not Available |
---|
CAS Registry Number | 481-30-1 |
---|
SMILES | Not Available |
---|
InChI Identifier | InChI=1S/C19H28O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h11,14-17,21H,3-10H2,1-2H3/t14-,15-,16-,17+,18-,19-/m0/s1 |
---|
InChI Key | MUMGGOZAMZWBJJ-KZYORJDKSA-N |
---|
Chemical Taxonomy |
---|
Description | belongs to the class of organic compounds known as androgens and derivatives. These are 3-hydroxylated C19 steroid hormones. They are known to favor the development of masculine characteristics. They also show profound effects on scalp and body hair in humans. |
---|
Kingdom | Organic compounds |
---|
Super Class | Lipids and lipid-like molecules |
---|
Class | Steroids and steroid derivatives |
---|
Sub Class | Androstane steroids |
---|
Direct Parent | Androgens and derivatives |
---|
Alternative Parents | |
---|
Substituents | - Androgen-skeleton
- 3-oxo-delta-4-steroid
- 3-oxosteroid
- Hydroxysteroid
- Oxosteroid
- 17-hydroxysteroid
- Delta-4-steroid
- Cyclohexenone
- Cyclic alcohol
- Secondary alcohol
- Ketone
- Cyclic ketone
- Organooxygen compound
- Alcohol
- Carbonyl group
- Organic oxygen compound
- Hydrocarbon derivative
- Organic oxide
- Aliphatic homopolycyclic compound
|
---|
Molecular Framework | Aliphatic homopolycyclic compounds |
---|
External Descriptors | |
---|
Ontology |
---|
Status | Detected and Quantified |
---|
Origin | |
---|
Biofunction | Not Available |
---|
Application | Not Available |
---|
Cellular locations | - Cell membrane
- Cytoplasm
- Membrane
|
---|
Physical Properties |
---|
State | Solid |
---|
Experimental Properties | Property | Value | Reference |
---|
Melting Point | Not Available | Not Available | Boiling Point | Not Available | Not Available | Water Solubility | Not Available | Not Available | LogP | Not Available | Not Available |
|
---|
Predicted Properties | Not Available |
---|
Spectra |
---|
Spectra | |
---|
Biological Properties |
---|
Cellular Locations | - Cell membrane
- Cytoplasm
- Membrane
|
---|
Biospecimen Locations | - Adrenal Gland
- Milk
- Ovary
- Prostate Tissue
- Testis
|
---|
Pathways | |
---|
Normal Concentrations |
---|
| |
Adrenal Gland | Expected but not Quantified | Not Quantified | Not Specified | Not Specified | Normal | | details | Milk | Detected and Quantified | 0.000245 uM | Not Specified | Not Specified | Normal | | details | Milk | Detected and Quantified | 0.000177 uM | Not Specified | Not Specified | Normal | | details | Milk | Detected and Quantified | 0.000344 uM | Not Specified | Not Specified | Normal | | details | Ovary | Expected but not Quantified | Not Quantified | Not Specified | Not Specified | Normal | | details | Prostate Tissue | Expected but not Quantified | Not Quantified | Not Specified | Not Specified | Normal | | details | Testis | Expected but not Quantified | Not Quantified | Not Specified | Not Specified | Normal | | details |
|
---|
Abnormal Concentrations |
---|
| Not Available |
---|
External Links |
---|
HMDB ID | HMDB0000628 |
---|
DrugBank ID | DB07768 |
---|
Phenol Explorer Compound ID | Not Available |
---|
FooDB ID | FDB011544 |
---|
KNApSAcK ID | Not Available |
---|
Chemspider ID | 9789 |
---|
KEGG Compound ID | Not Available |
---|
BioCyc ID | Not Available |
---|
BiGG ID | Not Available |
---|
Wikipedia Link | Epitestosterone |
---|
METLIN ID | 5601 |
---|
PubChem Compound | 10204 |
---|
PDB ID | Not Available |
---|
ChEBI ID | 42534 |
---|
References |
---|
Synthesis Reference | Alvarez, Francisco. Steroids. CCXLIX. A new synthesis of epitestosterone from pregnenolone acetate via nitrosation. Steroids (1963), 2(4), 393-8. |
---|
Material Safety Data Sheet (MSDS) | Not Available |
---|
General References | - Courant F, Antignac JP, Laille J, Monteau F, Andre F, Le Bizec B: Exposure assessment of prepubertal children to steroid endocrine disruptors. 2. Determination of steroid hormones in milk, egg, and meat samples. J Agric Food Chem. 2008 May 14;56(9):3176-84. doi: 10.1021/jf800096f. Epub 2008 Apr 16. [PubMed:18412364 ]
|
---|