| Record Information |
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| Version | 1.0 |
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| Creation Date | 2016-09-30 22:38:18 UTC |
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| Update Date | 2020-05-11 20:55:15 UTC |
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| BMDB ID | BMDB0000899 |
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| Secondary Accession Numbers | |
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| Metabolite Identification |
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| Common Name | Androstanedione |
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| Description | Androstanedione belongs to the class of organic compounds known as androgens and derivatives. These are 3-hydroxylated C19 steroid hormones. They are known to favor the development of masculine characteristics. They also show profound effects on scalp and body hair in humans. Thus, androstanedione is considered to be a steroid lipid molecule. Androstanedione exists as a solid, very hydrophobic, practically insoluble (in water), and relatively neutral molecule. Androstanedione exists in all living organisms, ranging from bacteria to humans. Androstanedione participates in a number of enzymatic reactions, within cattle. In particular, Androstanedione can be biosynthesized from androstenedione; which is mediated by the enzyme 3-oxo-5-alpha-steroid 4-dehydrogenase 1. In addition, Androstanedione can be converted into androsterone; which is catalyzed by the enzyme aldo-keto reductase family 1 member C4. In cattle, androstanedione is involved in the metabolic pathway called the androstenedione metabolism pathway. |
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| Structure | |
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| Synonyms | | Value | Source |
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| 5alpha-Androstan-3,17-dione | ChEBI | | 5a-Androstan-3,17-dione | Generator | | 5Α-androstan-3,17-dione | Generator | | (5a)-Androstane-3,17-dione | HMDB | | 5-alpha-Androstane-3,17-dione | HMDB | | 5a-Androsta-3,17-dione | HMDB | | 5a-Androstane-3, 17-dione | HMDB | | 5a-Androstane-3,17-dione | HMDB | | 5a-Androstanedione | HMDB | | 5alpha-Androstane-3,17-dione | HMDB | | Androstane-3,17-dione | HMDB | | Androstane-3,7-dione | HMDB | | Androstane-3,17-dione, (2-3(H)-labeled, (2beta,5beta))-isomer | HMDB | | Androstane-3,17-dione, (4-(3)H-labeled, (4alpha,5beta))-isomer | HMDB | | Androstane-3,17-dione, (2-3(H)-labeled, (2alpha,5beta))-isomer | HMDB | | Androstane-3,17-dione, (4-(3)H-labeled, (4beta,5beta))-isomer | HMDB | | Androstane-3,17-dione, (5beta)-isomer | HMDB | | 3,17-Dioxy-5 alpha-androstane | HMDB | | 5 alpha-Androstanedione | HMDB | | 5 beta-Androstane-3,17-dione | HMDB | | 5 alpha-Androstane-3,17-dione | HMDB | | Androstane-3,17-dione, (5alpha)-isomer | HMDB |
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| Chemical Formula | C19H28O2 |
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| Average Molecular Weight | 288.4244 |
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| Monoisotopic Molecular Weight | 288.20893014 |
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| IUPAC Name | Not Available |
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| Traditional Name | Not Available |
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| CAS Registry Number | 846-46-8 |
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| SMILES | Not Available |
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| InChI Identifier | InChI=1S/C19H28O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h12,14-16H,3-11H2,1-2H3/t12-,14-,15-,16-,18-,19-/m0/s1 |
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| InChI Key | RAJWOBJTTGJROA-WZNAKSSCSA-N |
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| Chemical Taxonomy |
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| Description | belongs to the class of organic compounds known as androgens and derivatives. These are 3-hydroxylated C19 steroid hormones. They are known to favor the development of masculine characteristics. They also show profound effects on scalp and body hair in humans. |
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| Kingdom | Organic compounds |
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| Super Class | Lipids and lipid-like molecules |
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| Class | Steroids and steroid derivatives |
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| Sub Class | Androstane steroids |
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| Direct Parent | Androgens and derivatives |
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| Alternative Parents | |
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| Substituents | - Androgen-skeleton
- 3-oxo-5-alpha-steroid
- Oxosteroid
- 17-oxosteroid
- 3-oxosteroid
- Cyclic ketone
- Ketone
- Organic oxygen compound
- Organic oxide
- Hydrocarbon derivative
- Organooxygen compound
- Carbonyl group
- Aliphatic homopolycyclic compound
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| Molecular Framework | Aliphatic homopolycyclic compounds |
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| External Descriptors | |
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| Ontology |
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| Status | Detected but not Quantified |
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| Origin | |
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| Biofunction | Not Available |
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| Application | Not Available |
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| Cellular locations | - Cell membrane
- Cytoplasm
- Endoplasmic reticulum
- Membrane
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| Physical Properties |
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| State | Solid |
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| Experimental Properties | | Property | Value | Reference |
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| Melting Point | 133.5 - 134.0 °C | Not Available | | Boiling Point | Not Available | Not Available | | Water Solubility | Not Available | Not Available | | LogP | Not Available | Not Available |
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| Predicted Properties | Not Available |
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| Spectra |
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| Spectra | |
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