| Record Information |
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| Version | 1.0 |
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| Creation Date | 2016-09-30 22:49:35 UTC |
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| Update Date | 2020-04-22 15:09:16 UTC |
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| BMDB ID | BMDB0001984 |
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| Secondary Accession Numbers | |
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| Metabolite Identification |
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| Common Name | Finasteride |
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| Description | Finasteride, also known as proscar or propecia, belongs to the class of organic compounds known as androgens and derivatives. These are 3-hydroxylated C19 steroid hormones. They are known to favor the development of masculine characteristics. They also show profound effects on scalp and body hair in humans. Based on a literature review a significant number of articles have been published on Finasteride. |
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| Structure | |
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| Synonyms | | Value | Source |
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| (5alpha,17beta)-(1,1-Dimethylethyl)-3-oxo-4-azaandrost-1-ene-17-carboxamide | ChEBI | | Finasterida | ChEBI | | Finasteridum | ChEBI | | Propecia | Kegg | | Proscar | Kegg | | (5a,17b)-(1,1-Dimethylethyl)-3-oxo-4-azaandrost-1-ene-17-carboxamide | Generator | | (5Α,17β)-(1,1-dimethylethyl)-3-oxo-4-azaandrost-1-ene-17-carboxamide | Generator | | Chibro-proscar | HMDB | | Finastid | HMDB | | Finpecia | HMDB | | Prostide | HMDB | | Chibro proscar | HMDB | | Eucoprost | HMDB | | Merck brand 1 OF finasteride | HMDB | | Merck brand 2 OF finasteride | HMDB | | Cahill may roberts brand OF finasteride | HMDB | | Lipha brand OF finasteride | HMDB | | Merck frosst brand 1 OF finasteride | HMDB | | Frosst iberica brand OF finasteride | HMDB | | MSD Chibropharm brand OF finasteride | HMDB | | Merck sharp and dohme brand 1 OF finasteride | HMDB | | Propeshia | HMDB | | MSD Brand OF finasteride | HMDB | | Merck frosst brand 2 OF finasteride | HMDB | | Merck sharp and dhome brand 2 OF finasteride | HMDB |
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| Chemical Formula | C23H36N2O2 |
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| Average Molecular Weight | 372.5441 |
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| Monoisotopic Molecular Weight | 372.277678406 |
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| IUPAC Name | (1S,2R,7R,10S,11S,14S,15S)-N-tert-butyl-2,15-dimethyl-5-oxo-6-azatetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-3-ene-14-carboxamide |
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| Traditional Name | (1S,2R,7R,10S,11S,14S,15S)-N-tert-butyl-2,15-dimethyl-5-oxo-6-azatetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-3-ene-14-carboxamide |
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| CAS Registry Number | 98319-26-7 |
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| SMILES | [H][C@@]12CC[C@H](C(=O)NC(C)(C)C)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC[C@@]2([H])NC(=O)C=C[C@]12C |
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| InChI Identifier | InChI=1S/C23H36N2O2/c1-21(2,3)25-20(27)17-8-7-15-14-6-9-18-23(5,13-11-19(26)24-18)16(14)10-12-22(15,17)4/h11,13-18H,6-10,12H2,1-5H3,(H,24,26)(H,25,27)/t14-,15-,16-,17+,18+,22-,23+/m0/s1 |
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| InChI Key | DBEPLOCGEIEOCV-WSBQPABSSA-N |
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| Chemical Taxonomy |
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| Description | belongs to the class of organic compounds known as androgens and derivatives. These are 3-hydroxylated C19 steroid hormones. They are known to favor the development of masculine characteristics. They also show profound effects on scalp and body hair in humans. |
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| Kingdom | Organic compounds |
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| Super Class | Lipids and lipid-like molecules |
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| Class | Steroids and steroid derivatives |
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| Sub Class | Androstane steroids |
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| Direct Parent | Androgens and derivatives |
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| Alternative Parents | |
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| Substituents | - 20-hydroxysteroid
- Androgen-skeleton
- 3-hydroxysteroid
- Hydroxysteroid
- 4-azasteroid
- Azasteroid
- Cyclic carboximidic acid
- Carboximidic acid
- Carboximidic acid derivative
- Azacycle
- Organoheterocyclic compound
- Propargyl-type 1,3-dipolar organic compound
- Organic 1,3-dipolar compound
- Organic oxygen compound
- Organopnictogen compound
- Organonitrogen compound
- Organooxygen compound
- Hydrocarbon derivative
- Organic nitrogen compound
- Aliphatic heteropolycyclic compound
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| Molecular Framework | Aliphatic heteropolycyclic compounds |
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| External Descriptors | |
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| Ontology |
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| Status | Expected but not Quantified |
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| Origin | |
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| Biofunction | Not Available |
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| Application | Not Available |
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| Cellular locations | - Cell membrane
- Cytoplasm
- Membrane
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| Physical Properties |
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| State | Solid |
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| Experimental Properties | | Property | Value | Reference |
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| Melting Point | Not Available | Not Available | | Boiling Point | Not Available | Not Available | | Water Solubility | Not Available | Not Available | | LogP | Not Available | Not Available |
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| Predicted Properties | |
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| Spectra |
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| Spectra | |
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