Showing metabocard for Pantetheine (BMDB0003426)

General function:

Lipid transport and metabolism

Specific function:

Catalyzes the synthesis of acetyl-CoA from short-chain fatty acids (By similarity). Propionate is the preferred substrate but can also utilize acetate and butyrate with a much lower affinity.

Gene Name:

ACSS3

Uniprot ID:

A7MB45

Molecular weight:

74805.0

Reactions

General function:

Secondary metabolites biosynthesis, transport and catabolism

Specific function:

Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. This multifunctional protein has 7 catalytic activities as an acyl carrier protein.

Gene Name:

FASN

Uniprot ID:

Q71SP7

Molecular weight:

274554.0

General function:

Involved in pantetheine hydrolase activity

Specific function:

Amidohydrolase that hydrolyzes specifically one of the carboamide linkages in D-pantetheine thus recycling pantothenic acid (vitamin B5) and releasing cysteamine.

Gene Name:

VNN1

Uniprot ID:

Q58CQ9

Molecular weight:

56947.0

Reactions

General function:

Lipid transport and metabolism

Specific function:

Carrier of the growing fatty acid chain in fatty acid biosynthesis (PubMed:1907568). Accessory and non-catalytic subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain (PubMed:1907568, PubMed:10852722, PubMed:18721790).

Gene Name:

NDUFAB1

Uniprot ID:

P52505

Molecular weight:

17402.0

General function:

Involved in ATP binding

Specific function:

Plays a role in the physiological regulation of coenzyme A (CoA) levels.

Gene Name:

PANK3

Uniprot ID:

Q08DA5

Molecular weight:

41117.0

Reactions

General function:

Not Available

Specific function:

Not Available

Gene Name:

AceCS2

Uniprot ID:

Q9BEA3

Molecular weight:

74310.0

Reactions