Showing metabocard for TG(20:0/20:0/20:0) (BMDB0005414)

IdentificationTaxonomyPhysical propertiesPathwaysSpectraConcentrationsLinksReferencesenzymes (1) Show 1 proteinXML
Record Information
Version1.0
Creation Date2016-09-30 23:16:48 UTC
Update Date2020-05-21 16:27:58 UTC
BMDB IDBMDB0005414
Secondary Accession Numbers
  • BMDB05414
Metabolite Identification
Common NameTG(20:0/20:0/20:0)
DescriptionTG(20:0/20:0/20:0), also known as tg(20:0/20:0/20:0) or tg(20:0/20:0/20:0), belongs to the class of organic compounds known as tg(20:0/20:0/20:0)s. These are glycerides consisting of three fatty acid chains covalently bonded to a glycerol molecule through ester linkages. Thus, TG(20:0/20:0/20:0) is considered to be a triradylglycerol lipid molecule. TG(20:0/20:0/20:0) is a very hydrophobic molecule, practically insoluble (in water), and relatively neutral. TG(20:0/20:0/20:0) can be biosynthesized from DG(20:0/20:0/0:0) and eicosanoyl-CoA; which is catalyzed by the enzyme diacylglycerol O-acyltransferase. In cattle, TG(20:0/20:0/20:0) is involved in the metabolic pathway called de novo tg(20:0/20:0/20:0) biosynthesis TG(20:0/20:0/20:0) pathway.
Structure
Thumb
MOLSDFPDBSMILESInChI
Synonyms
ValueSource
TG(20:0/20:0/20:0)Lipid Annotator
TriglycerideLipid Annotator, HMDB
TAG(60:0)Lipid Annotator, HMDB
Tracylglycerol(20:0/20:0/20:0)Lipid Annotator, HMDB
TG(60:0)Lipid Annotator, HMDB
1-arachidonyl-2-arachidonyl-3-arachidonyl-glycerolLipid Annotator, HMDB
TAG(20:0/20:0/20:0)Lipid Annotator, HMDB
Tracylglycerol(60:0)Lipid Annotator, HMDB
1-eicosanoyl-2-eicosanoyl-3-eicosanoyl-glycerolLipid Annotator, HMDB
TriacylglycerolLipid Annotator, HMDB
Chemical FormulaC63H122O6
Average Molecular Weight975.6392
Monoisotopic Molecular Weight974.924141636
IUPAC Name1,3-bis(icosanoyloxy)propan-2-yl icosanoate
Traditional Nametriglyceride
CAS Registry NumberNot Available
SMILES
[H]C(COC(=O)CCCCCCCCCCCCCCCCCCC)(COC(=O)CCCCCCCCCCCCCCCCCCC)OC(=O)CCCCCCCCCCCCCCCCCCC
InChI Identifier
InChI=1S/C63H122O6/c1-4-7-10-13-16-19-22-25-28-31-34-37-40-43-46-49-52-55-61(64)67-58-60(69-63(66)57-54-51-48-45-42-39-36-33-30-27-24-21-18-15-12-9-6-3)59-68-62(65)56-53-50-47-44-41-38-35-32-29-26-23-20-17-14-11-8-5-2/h60H,4-59H2,1-3H3
InChI KeyKCVWRCXEUJUXIG-UHFFFAOYSA-N
Chemical Taxonomy
Description belongs to the class of organic compounds known as triacylglycerols. These are glycerides consisting of three fatty acid chains covalently bonded to a glycerol molecule through ester linkages.
KingdomOrganic compounds
Super ClassLipids and lipid-like molecules
ClassGlycerolipids
Sub ClassTriradylcglycerols
Direct ParentTriacylglycerols
Alternative Parents
Substituents
  • Triacyl-sn-glycerol
  • Tricarboxylic acid or derivatives
  • Fatty acid ester
  • Fatty acyl
  • Carboxylic acid ester
  • Carboxylic acid derivative
  • Organic oxygen compound
  • Organic oxide
  • Hydrocarbon derivative
  • Organooxygen compound
  • Carbonyl group
  • Aliphatic acyclic compound
Molecular FrameworkAliphatic acyclic compounds
External Descriptors
Ontology
StatusExpected but not Quantified
Origin
  • Endogenous
  • Exogenous
BiofunctionNot Available
ApplicationNot Available
Cellular locations
  • Adiposome
  • Cell membrane
  • Membrane
Physical Properties
StateSolid
Experimental Properties
PropertyValueReference
Melting PointNot AvailableNot Available
Boiling PointNot AvailableNot Available
Water SolubilityNot AvailableNot Available
LogPNot AvailableNot Available
Predicted Properties
PropertyValueSource
logP10.67ALOGPS
logP24.26ChemAxon
logS-7.9ALOGPS
pKa (Strongest Basic)-6.6ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count3ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area78.9 ŲChemAxon
Rotatable Bond Count62ChemAxon
Refractivity296.5 m³·mol⁻¹ChemAxon
Polarizability135.29 ųChemAxon
Number of Rings0ChemAxon
BioavailabilityYesChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleYesChemAxon
Spectra
Spectra
Biological Properties
Cellular Locations
  • Adiposome
  • Cell membrane
  • Membrane
Biospecimen LocationsNot Available
Pathways
Normal Concentrations
Not Available
Abnormal Concentrations
Not Available
HMDB IDHMDB0005414
DrugBank IDNot Available
Phenol Explorer Compound IDNot Available
FooDB IDFDB000704
KNApSAcK IDNot Available
Chemspider ID455365
KEGG Compound IDC00422
BioCyc IDNot Available
BiGG IDNot Available
Wikipedia LinkNot Available
METLIN ID4702
PubChem Compound522017
PDB IDNot Available
ChEBI IDNot Available
References
Synthesis ReferenceNot Available
Material Safety Data Sheet (MSDS)Not Available
General ReferencesNot Available

Enzymes

Enzyme Details
1. Diacylglycerol O-acyltransferase 1
General function:
Not Available
Specific function:
Catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. In contrast to DGAT2 it is not essential for survival. May be involved in VLDL (very low density lipoprotein) assembly. Functions as the major acyl-CoA retinol acyltransferase (ARAT) in the skin, where it acts to maintain retinoid homeostasis and prevent retinoid toxicity leading to skin and hair disorders. In liver, plays a role in esterifying exogenous fatty acids to glycerol.
Gene Name:
DGAT1
Uniprot ID:
Q8MK44
Molecular weight:
55602.0
Reactions
DG(20:0/20:0/0:0) + Eicosanoyl-CoA → TG(20:0/20:0/20:0) + Coenzyme Adetails