| Record Information |
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| Version | 1.0 |
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| Creation Date | 2016-09-30 23:25:51 UTC |
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| Update Date | 2020-04-22 15:18:32 UTC |
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| BMDB ID | BMDB0006770 |
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| Secondary Accession Numbers | |
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| Metabolite Identification |
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| Common Name | 5b-Dihydrotestosterone |
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| Description | 5b-Dihydrotestosterone, also known as 5-beta-DHT or 5-β-DHT, belongs to the class of organic compounds known as androgens and derivatives. These are 3-hydroxylated C19 steroid hormones. They are known to favor the development of masculine characteristics. They also show profound effects on scalp and body hair in humans. Thus, 5b-dihydrotestosterone is considered to be a steroid lipid molecule. 5b-Dihydrotestosterone is a very hydrophobic molecule, practically insoluble (in water), and relatively neutral. 5b-Dihydrotestosterone can be converted into testosterone through its interaction with the enzyme 3-oxo-5-beta-steroid 4-dehydrogenase. In cattle, 5b-dihydrotestosterone is involved in the metabolic pathway called the androgen and estrogen metabolism pathway. |
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| Structure | |
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| Synonyms | | Value | Source |
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| (5beta,17beta)-17-Hydroxyandrostan-3-one | ChEBI | | (5beta,8alpha,17beta)-17-Hydroxyandrostan-3-one | ChEBI | | 17beta-Hydroxyetiocholan-3-one | ChEBI | | 5-beta-DHT | ChEBI | | 5beta,17beta-Hydroxyandrostan-3-one | ChEBI | | 5beta-Androstan-17beta-ol-3-one | ChEBI | | Etiocholan-17-beta-ol-3-one | ChEBI | | (5b,17b)-17-Hydroxyandrostan-3-one | Generator | | (5Β,17β)-17-hydroxyandrostan-3-one | Generator | | (5b,8a,17b)-17-Hydroxyandrostan-3-one | Generator | | (5Β,8α,17β)-17-hydroxyandrostan-3-one | Generator | | 17b-Hydroxyetiocholan-3-one | Generator | | 17Β-hydroxyetiocholan-3-one | Generator | | 5-b-DHT | Generator | | 5-Β-DHT | Generator | | 5b,17b-Hydroxyandrostan-3-one | Generator | | 5Β,17β-hydroxyandrostan-3-one | Generator | | 5b-Androstan-17b-ol-3-one | Generator | | 5Β-androstan-17β-ol-3-one | Generator | | Etiocholan-17-b-ol-3-one | Generator | | Etiocholan-17-β-ol-3-one | Generator | | 5beta-Dihydrotestosterone | HMDB | | 17beta-Hydroxy-5beta-androstan-3-one | HMDB |
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| Chemical Formula | C19H30O2 |
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| Average Molecular Weight | 290.4403 |
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| Monoisotopic Molecular Weight | 290.224580204 |
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| IUPAC Name | Not Available |
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| Traditional Name | Not Available |
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| CAS Registry Number | 571-22-2 |
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| SMILES | Not Available |
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| InChI Identifier | InChI=1S/C19H30O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h12,14-17,21H,3-11H2,1-2H3/t12-,14+,15+,16+,17+,18+,19+/m1/s1 |
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| InChI Key | NVKAWKQGWWIWPM-MISPCMORSA-N |
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| Chemical Taxonomy |
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| Description | belongs to the class of organic compounds known as androgens and derivatives. These are 3-hydroxylated C19 steroid hormones. They are known to favor the development of masculine characteristics. They also show profound effects on scalp and body hair in humans. |
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| Kingdom | Organic compounds |
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| Super Class | Lipids and lipid-like molecules |
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| Class | Steroids and steroid derivatives |
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| Sub Class | Androstane steroids |
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| Direct Parent | Androgens and derivatives |
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| Alternative Parents | |
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| Substituents | - Androgen-skeleton
- 3-oxosteroid
- 3-oxo-5-beta-steroid
- 17-hydroxysteroid
- Oxosteroid
- Hydroxysteroid
- Cyclic alcohol
- Cyclic ketone
- Secondary alcohol
- Ketone
- Organic oxygen compound
- Organooxygen compound
- Hydrocarbon derivative
- Carbonyl group
- Organic oxide
- Alcohol
- Aliphatic homopolycyclic compound
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| Molecular Framework | Aliphatic homopolycyclic compounds |
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| External Descriptors | |
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| Ontology |
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| Status | Expected but not Quantified |
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| Origin | |
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| Biofunction | Not Available |
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| Application | Not Available |
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| Cellular locations | - Cell membrane
- Cytoplasm
- Membrane
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| Physical Properties |
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| State | Solid |
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| Experimental Properties | | Property | Value | Reference |
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| Melting Point | Not Available | Not Available | | Boiling Point | Not Available | Not Available | | Water Solubility | Not Available | Not Available | | LogP | Not Available | Not Available |
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| Predicted Properties | Not Available |
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| Spectra |
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| Spectra | |
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