Showing metabocard for PG(16:0/18:1(11Z)) (BMDB0010573)

IdentificationTaxonomyPhysical propertiesPathwaysSpectraConcentrationsLinksReferencesXML
Record Information
Version1.0
Creation Date2016-10-03 18:09:31 UTC
Update Date2020-05-20 22:51:30 UTC
BMDB IDBMDB0010573
Secondary Accession Numbers
  • BMDB10573
Metabolite Identification
Common NamePG(16:0/18:1(11Z))
DescriptionPG(16:0/18:1(11Z)), also known as GPG(16:0/18:1) or GPG(34:1), belongs to the class of organic compounds known as phosphatidylglycerols. These are glycerophosphoglycerols in which two fatty acids are bonded to the 1-glycerol moiety through ester linkages. As is the case with diacylglycerols, phosphatidylglycerols can have many different combinations of fatty acids of varying lengths and saturation attached to the C-1 and C-2 positions. Thus, PG(16:0/18:1(11Z)) is considered to be a glycerophosphoglycerol lipid molecule. PG(16:0/18:1(11Z)) is a very hydrophobic molecule, practically insoluble (in water), and relatively neutral. PG(16:0/18:1(11Z)) exists in all living species, ranging from bacteria to humans. PG(16:0/18:1(11Z)) participates in a number of enzymatic reactions, within cattle. In particular, PG(16:0/18:1(11Z)) can be biosynthesized from PGP(16:0/18:1(11Z)); which is mediated by the enzyme phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1. In addition, PG(16:0/18:1(11Z)) and CDP-DG(16:0/18:1(11Z)) can be converted into CL(16:0/18:1(11Z)/16:0/18:1(11Z)) and cytidine monophosphate through the action of the enzyme cardiolipin synthase. In cattle, PG(16:0/18:1(11Z)) is involved in the metabolic pathway called cardiolipin biosynthesis CL(16:0/18:1(11Z)/16:0/18:1(11Z)) pathway.
Structure
Thumb
MOLSDFPDBSMILESInChI
Synonyms
ValueSource
PG(34:1)Lipid Annotator, HMDB
PG(16:0/18:1(11Z))Lipid Annotator
Phosphatidylglycerol(34:1)Lipid Annotator, HMDB
1-hexadecanoyl-2-(11Z-octadecenoyl)-sn-glycero-3-phospho-(1'-glycerol)Lipid Annotator, HMDB
GPG(16:0/18:1)Lipid Annotator, HMDB
Phosphatidylglycerol(16:0/18:1)Lipid Annotator, HMDB
1-palmitoyl-2-vaccenoyl-sn-glycero-3-phosphoglycerolLipid Annotator, HMDB
PG(16:0/18:1)Lipid Annotator, HMDB
1-hexadecanoyl-2-(11Z-octadecenoyl)-sn-glycero-3-phosphoglycerolLipid Annotator, HMDB
GPG(34:1)Lipid Annotator, HMDB
GPG(16:0/18:1N7)HMDB
GPG(16:0/18:1W7)HMDB
PG(16:0/18:1N7)HMDB
PG(16:0/18:1W7)HMDB
Phosphatidylglycerol(16:0/18:1n7)HMDB
Phosphatidylglycerol(16:0/18:1W7)HMDB
1-Palmitoyl-2-cis-vaccenoyl-sn-glycero-3-phospho-(1'-glycerol)HMDB
1-Palmitoyl-2-cis-vaccenoyl-sn-glycero-3-phospho-(1’-glycerol)HMDB
1-Palmitoyl-2-cis-vaccenoyl-sn-glycero-3-phosphoglycerolHMDB
1-Palmitoyl-2-oleoyl-GPGHMDB
Phosphatidylglycerol(16:0/18:1(11Z))HMDB
1-Palmitoyl-2-cis-vaccenoyl-GPGHMDB
GPG(16:0/18:1(11Z))HMDB
Chemical FormulaC40H77O10P
Average Molecular Weight749.0071
Monoisotopic Molecular Weight748.525435196
IUPAC Name[(2S)-2,3-dihydroxypropoxy][(2R)-3-(hexadecanoyloxy)-2-[(11Z)-octadec-11-enoyloxy]propoxy]phosphinic acid
Traditional Name(2S)-2,3-dihydroxypropoxy(2R)-3-(hexadecanoyloxy)-2-[(11Z)-octadec-11-enoyloxy]propoxyphosphinic acid
CAS Registry NumberNot Available
SMILES
[H][C@](O)(CO)COP(O)(=O)OC[C@@]([H])(COC(=O)CCCCCCCCCCCCCCC)OC(=O)CCCCCCCCC\C=C/CCCCCC
InChI Identifier
InChI=1S/C40H77O10P/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-40(44)50-38(36-49-51(45,46)48-34-37(42)33-41)35-47-39(43)31-29-27-25-23-21-19-16-14-12-10-8-6-4-2/h13,15,37-38,41-42H,3-12,14,16-36H2,1-2H3,(H,45,46)/b15-13-/t37-,38+/m0/s1
InChI KeyADYWCMPUNIVOEA-GPJPVTGXSA-N
Chemical Taxonomy
Description belongs to the class of organic compounds known as phosphatidylglycerols. These are glycerophosphoglycerols in which two fatty acids are bonded to the 1-glycerol moiety through ester linkages. As is the case with diacylglycerols, phosphatidylglycerols can have many different combinations of fatty acids of varying lengths and saturation attached to the C-1 and C-2 positions.
KingdomOrganic compounds
Super ClassLipids and lipid-like molecules
ClassGlycerophospholipids
Sub ClassGlycerophosphoglycerols
Direct ParentPhosphatidylglycerols
Alternative Parents
Substituents
  • 1,2-diacylglycerophosphoglycerol
  • Fatty acid ester
  • Dialkyl phosphate
  • Dicarboxylic acid or derivatives
  • Organic phosphoric acid derivative
  • Phosphoric acid ester
  • Alkyl phosphate
  • Fatty acyl
  • 1,2-diol
  • Carboxylic acid ester
  • Secondary alcohol
  • Carboxylic acid derivative
  • Organic oxide
  • Organooxygen compound
  • Alcohol
  • Organic oxygen compound
  • Primary alcohol
  • Carbonyl group
  • Hydrocarbon derivative
  • Aliphatic acyclic compound
Molecular FrameworkAliphatic acyclic compounds
External Descriptors
Ontology
StatusExpected but not Quantified
Origin
  • Endogenous
  • Exogenous
BiofunctionNot Available
ApplicationNot Available
Cellular locations
  • Cell membrane
  • Intracellular membrane
  • Membrane
Physical Properties
StateSolid
Experimental Properties
PropertyValueReference
Melting PointNot AvailableNot Available
Boiling PointNot AvailableNot Available
Water SolubilityNot AvailableNot Available
LogPNot AvailableNot Available
Predicted Properties
PropertyValueSource
logP8.16ALOGPS
logP11.46ChemAxon
logS-6.9ALOGPS
pKa (Strongest Acidic)1.89ChemAxon
pKa (Strongest Basic)-3ChemAxon
Physiological Charge-1ChemAxon
Hydrogen Acceptor Count6ChemAxon
Hydrogen Donor Count3ChemAxon
Polar Surface Area148.82 ŲChemAxon
Rotatable Bond Count41ChemAxon
Refractivity205.63 m³·mol⁻¹ChemAxon
Polarizability90.5 ųChemAxon
Number of Rings0ChemAxon
BioavailabilityYesChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleYesChemAxon
Spectra
Spectra
Biological Properties
Cellular Locations
  • Cell membrane
  • Intracellular membrane
  • Membrane
Biospecimen Locations
  • All Tissues
  • Placenta
Pathways
Normal Concentrations
BiospecimenStatusValueAgeSexConditionReferenceDetails
All TissuesExpected but not QuantifiedNot QuantifiedNot SpecifiedNot SpecifiedNormal
  • Not Applicable
 details
PlacentaExpected but not QuantifiedNot QuantifiedNot SpecifiedNot SpecifiedNormal
  • Not Applicable
 details
Abnormal Concentrations
Not Available
HMDB IDHMDB0010573
DrugBank IDNot Available
Phenol Explorer Compound IDNot Available
FooDB IDFDB027723
KNApSAcK IDNot Available
Chemspider ID4451166
KEGG Compound IDNot Available
BioCyc IDNot Available
BiGG IDNot Available
Wikipedia LinkNot Available
METLIN IDNot Available
PubChem Compound5289145
PDB IDPGV
ChEBI ID44946
References
Synthesis ReferenceNot Available
Material Safety Data Sheet (MSDS)Not Available
General ReferencesNot Available