Showing metabocard for PC(P-16:0/20:4(5Z,8Z,11Z,14Z)) (BMDB0011220)

IdentificationTaxonomyPhysical propertiesPathwaysSpectraConcentrationsLinksReferencesXML
Record Information
Version1.0
Creation Date2016-10-03 18:14:44 UTC
Update Date2020-06-04 19:13:58 UTC
BMDB IDBMDB0011220
Secondary Accession Numbers
  • BMDB11220
Metabolite Identification
Common NamePC(P-16:0/20:4(5Z,8Z,11Z,14Z))
DescriptionPC(P-16:0/20:4(5Z,8Z,11Z,14Z)) is a phosphatidylchloline (PC). It is a glycerophospholipid in which a phosphorylcholine moiety occupies a glycerol substitution site. As is the case with diacylglycerols, phosphatidylcholines can have many different combinations of fatty acids of varying lengths and saturation attached to the C-1 and C-2 positions. PC(P-16:0/20:4(5Z,8Z,11Z,14Z)), in particular, consists of one 1Z-hexadecenyl chain to the C-1 atom, and one 5Z,8Z,11Z,14Z-eicosatetraenoyl to the C-2 atom. In E. coli, PCs can be found in the integral component of the cell outer membrane. They are hydrolyzed by Phospholipases to a 2-acylglycerophosphocholine and a carboxylate.
Structure
Thumb
MOLSDFPDBSMILESInChI
Synonyms
ValueSource
1-(1-Enyl-palmitoyl)-2-arachidonoyl-GPCHMDB
1-(1-Enyl-palmitoyl)-2-arachidonoyl-GPC (p-16:0/20:4)HMDB
1-(1Z)-Hexadecenyl-2 (5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholineHMDB
1-(1Z)-Hexadecenyl-2 (5Z,8Z,11Z,14Z)-icosatetraenoyl-sn-glycero-3-phosphocholineHMDB
1-O-(1Z)-Hexadecenyl-2 (5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholineHMDB
GPC(p-16:0/20:4)HMDB
PC(O-16:1(1Z)/20:4 (5Z,8Z,11Z,14Z))HMDB
PC(p-16:0/20:4)HMDB
1-(1Z-Hexadecenyl)-2-arachidonoyl-GPCHMDB
1-(1Z-Hexadecenyl)-2-arachidonoyl-sn-glycero-3-phosphocholineHMDB
1-(1Z-Hexadecenyl)-2-arachidonoyl-sn-glycero-phosphatidylcholineHMDB
GPC(16:1/20:4)HMDB
GPC(36:5)HMDB
GPC(O-16:1(1Z)/20:4(5Z,8Z,11Z,14Z))HMDB
GPC(O-16:1(1Z)/20:4n6)HMDB
GPC(O-16:1(1Z)/20:4W6)HMDB
GPC(p-16:0/20:4(5Z,8Z,11Z,14Z))HMDB
GPC(p-16:0/20:4n6)HMDB
GPC(p-16:0/20:4W6)HMDB
GPCho(16:1/20:4)HMDB
GPCho(36:5)HMDB
GPCho(O-16:1(1Z)/20:4(5Z,8Z,11Z,14Z))HMDB
GPCho(O-16:1(1Z)/20:4n6)HMDB
GPCho(O-16:1(1Z)/20:4W6)HMDB
GPCho(p-16:0/20:4(5Z,8Z,11Z,14Z))HMDB
GPCho(p-16:0/20:4n6)HMDB
GPCho(p-16:0/20:4W6)HMDB
PC(16:1/20:4)HMDB
PC(36:5)HMDB
PC(O-16:1(1Z)/20:4(5Z,8Z,11Z,14Z))HMDB
PC(O-16:1(1Z)/20:4n6)HMDB
PC(O-16:1(1Z)/20:4W6)HMDB
PC(p-16:0/20:4n6)HMDB
PC(p-16:0/20:4W6)HMDB
Phosphatidylcholine(16:1/20:4)HMDB
Phosphatidylcholine(36:5)HMDB
Phosphatidylcholine(O-16:1(1Z)/20:4(5Z,8Z,11Z,14Z))HMDB
Phosphatidylcholine(O-16:1(1Z)/20:4n6)HMDB
Phosphatidylcholine(O-16:1(1Z)/20:4W6)HMDB
Phosphatidylcholine(p-16:0/20:4(5Z,8Z,11Z,14Z))HMDB
Phosphatidylcholine(p-16:0/20:4n6)HMDB
Phosphatidylcholine(p-16:0/20:4W6)HMDB
Chemical FormulaC44H80NO7P
Average Molecular Weight766.0823
Monoisotopic Molecular Weight765.567240431
IUPAC Name(2-{[(2R)-3-[(1Z)-hexadec-1-en-1-yloxy]-2-[(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoyloxy]propyl phosphonato]oxy}ethyl)trimethylazanium
Traditional Name(2-{[(2R)-3-[(1Z)-hexadec-1-en-1-yloxy]-2-[(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoyloxy]propyl phosphonato]oxy}ethyl)trimethylazanium
CAS Registry NumberNot Available
SMILES
CCCCCCCCCCCCCC\C=C/OC[C@]([H])(COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC
InChI Identifier
InChI=1S/C44H80NO7P/c1-6-8-10-12-14-16-18-20-22-23-24-25-27-29-31-33-35-37-44(46)52-43(42-51-53(47,48)50-40-38-45(3,4)5)41-49-39-36-34-32-30-28-26-21-19-17-15-13-11-9-7-2/h14,16,20,22,24-25,29,31,36,39,43H,6-13,15,17-19,21,23,26-28,30,32-35,37-38,40-42H2,1-5H3/b16-14-,22-20-,25-24-,31-29-,39-36-/t43-/m1/s1
InChI KeyIOYKZPNDXIIXLN-LOQSCQKMSA-N
Chemical Taxonomy
Description belongs to the class of organic compounds known as 1-(1z-alkenyl),2-acyl-glycerophosphocholines. These are glycerophosphocholines that carry exactly one acyl chain attached to the glycerol moiety through an ester linkage at the O2-position, and one 1Z-alkenyl chain attached through an ether linkage at the O1-position.
KingdomOrganic compounds
Super ClassLipids and lipid-like molecules
ClassGlycerophospholipids
Sub ClassGlycerophosphocholines
Direct Parent1-(1Z-alkenyl),2-acyl-glycerophosphocholines
Alternative Parents
Substituents
  • 1-(1z-alkenyl),2-acyl-glycerophosphocholine
  • Phosphocholine
  • Glycerol vinyl ether
  • Fatty acid ester
  • Dialkyl phosphate
  • Organic phosphoric acid derivative
  • Phosphoric acid ester
  • Alkyl phosphate
  • Fatty acyl
  • Quaternary ammonium salt
  • Tetraalkylammonium salt
  • Carboxylic acid ester
  • Monocarboxylic acid or derivatives
  • Carboxylic acid derivative
  • Amine
  • Organic oxide
  • Organopnictogen compound
  • Organooxygen compound
  • Organonitrogen compound
  • Organic oxygen compound
  • Organic nitrogen compound
  • Carbonyl group
  • Hydrocarbon derivative
  • Organic salt
  • Aliphatic acyclic compound
Molecular FrameworkAliphatic acyclic compounds
External Descriptors
  • 1-O-(alk-1-enyl)-2-O-acyl-sn-glycero-3-phosphocholine (CHEBI:77292 )
  • 1-(1Z-alkenyl),2-acylglycerophosphocholines (LMGP01030010 )
Ontology
StatusExpected but not Quantified
Origin
  • Endogenous
  • Exogenous
BiofunctionNot Available
ApplicationNot Available
Cellular locations
  • Cell membrane
  • Intracellular membrane
  • Membrane
Physical Properties
StateSolid
Experimental Properties
PropertyValueReference
Melting PointNot AvailableNot Available
Boiling PointNot AvailableNot Available
Water SolubilityNot AvailableNot Available
LogPNot AvailableNot Available
Predicted Properties
PropertyValueSource
logP6.07ALOGPS
logP8.84ChemAxon
logS-7.4ALOGPS
pKa (Strongest Acidic)1.86ChemAxon
pKa (Strongest Basic)-4.7ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count4ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area94.12 ŲChemAxon
Rotatable Bond Count39ChemAxon
Refractivity239.07 m³·mol⁻¹ChemAxon
Polarizability92.42 ųChemAxon
Number of Rings0ChemAxon
BioavailabilityYesChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleYesChemAxon
Spectra
Spectra
Spectrum TypeDescriptionSplash Key
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 10V, Negativesplash10-03di-0000000900-74925401eb11a223000fView in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 20V, Negativesplash10-03di-0021010900-664825f20d027ba0d235View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 40V, Negativesplash10-0udr-7179200000-e2c7c8e9a53730b3566aView in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 10V, Negativesplash10-0udi-0000000090-1097a3dda9c044f6ac84View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 20V, Negativesplash10-0udi-0000000090-1097a3dda9c044f6ac84View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 40V, Negativesplash10-0udi-0004921610-663b5d02daee79976c1aView in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 10V, Positivesplash10-014i-0000000900-15e652a3c47d2e3a33b1View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 20V, Positivesplash10-00lr-0900000500-b61bf5b02c50b97fb41eView in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 40V, Positivesplash10-05o0-0500210900-4fd3060f378d9dbff3b1View in MoNA
Biological Properties
Cellular Locations
  • Cell membrane
  • Intracellular membrane
  • Membrane
Biospecimen Locations
  • All Tissues
  • Placenta
Pathways
Normal Concentrations
BiospecimenStatusValueAgeSexConditionReferenceDetails
All TissuesExpected but not QuantifiedNot QuantifiedNot SpecifiedNot SpecifiedNormal
  • Not Applicable
 details
PlacentaExpected but not QuantifiedNot QuantifiedNot SpecifiedNot SpecifiedNormal
  • Not Applicable
 details
Abnormal Concentrations
Not Available
HMDB IDHMDB0011220
DrugBank IDNot Available
Phenol Explorer Compound IDNot Available
FooDB IDFDB027975
KNApSAcK IDNot Available
Chemspider IDNot Available
KEGG Compound IDNot Available
BioCyc IDNot Available
BiGG IDNot Available
Wikipedia LinkNot Available
METLIN IDNot Available
PubChem Compound24779388
PDB IDNot Available
ChEBI ID77292
References
Synthesis ReferenceNot Available
Material Safety Data Sheet (MSDS)Not Available
General ReferencesNot Available