Showing metabocard for gamma-Glutamylhistidine (BMDB0064156)

IdentificationTaxonomyPhysical propertiesPathwaysSpectraConcentrationsLinksReferencesXML
Record Information
Version1.0
Creation Date2020-03-03 19:44:06 UTC
Update Date2020-05-11 20:43:05 UTC
BMDB IDBMDB0064156
Secondary Accession Numbers
  • BMDB64156
Metabolite Identification
Common Namegamma-Glutamylhistidine
Descriptiongamma-Glutamylhistidine, also known as ge-H dipeptide or γ-L-glutamyl-L-histidine, belongs to the class of organic compounds known as dipeptides. These are organic compounds containing a sequence of exactly two alpha-amino acids joined by a peptide bond. Based on a literature review a small amount of articles have been published on gamma-Glutamylhistidine.
Structure
Thumb
MOLSDF3D-SDFPDBSMILESInChI View 3D Structure
Synonyms
ValueSource
L-gamma-Glu-L-hisChEBI
L-g-Glu-L-hisGenerator
L-Γ-glu-L-hisGenerator
g-GlutamylhistidineGenerator
Γ-glutamylhistidineGenerator
gamma-Glutamate histidine dipeptideHMDB
gamma-Glutamate-histidine dipeptideHMDB
GE-H dipeptideHMDB
GEH dipeptideHMDB
GGlu-hisHMDB
L-gamma-Glutamyl-L-histidineHMDB
Γ-glu-hisHMDB
Γ-L-glu-L-hisHMDB
Γ-L-glutamyl-L-histidineHMDB
L-Γ-glutamyl-L-histidineHMDB
N-Γ-glutamylhistidineHMDB
N-L-Γ-glutamylhistidineHMDB
N-L-Γ-glutamyl-L-histidineHMDB
gamma-Glu-hisHMDB
gamma-L-Glu-L-hisHMDB
gamma-L-Glutamyl-L-histidineHMDB
N-gamma-GlutamylhistidineHMDB
N-L-gamma-GlutamylhistidineHMDB
N-L-gamma-Glutamyl-L-histidineHMDB
N-Γ-L-glutamyl-L-histidineHMDB
N-gamma-L-Glutamyl-L-histidineHMDB
g-Glu-hisHMDB
gamma-GlutamylhistidineHMDB, ChEBI
Chemical FormulaC11H16N4O5
Average Molecular Weight284.272
Monoisotopic Molecular Weight284.112069631
IUPAC Name(2S)-2-amino-4-{[(1S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]carbamoyl}butanoic acid
Traditional Name(2S)-2-amino-4-{[(1S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]carbamoyl}butanoic acid
CAS Registry NumberNot Available
SMILES
N[C@@H](CCC(=O)N[C@@H](CC1=CNC=N1)C(O)=O)C(O)=O
InChI Identifier
InChI=1S/C11H16N4O5/c12-7(10(17)18)1-2-9(16)15-8(11(19)20)3-6-4-13-5-14-6/h4-5,7-8H,1-3,12H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20)/t7-,8-/m0/s1
InChI KeyPXVCMZCJAUJLJP-YUMQZZPRSA-N
Chemical Taxonomy
Description belongs to the class of organic compounds known as dipeptides. These are organic compounds containing a sequence of exactly two alpha-amino acids joined by a peptide bond.
KingdomOrganic compounds
Super ClassOrganic acids and derivatives
ClassCarboxylic acids and derivatives
Sub ClassAmino acids, peptides, and analogues
Direct ParentDipeptides
Alternative Parents
Substituents
  • Alpha-dipeptide
  • Gamma-glutamyl alpha-amino acid
  • Histidine or derivatives
  • Glutamine or derivatives
  • N-acyl-alpha-amino acid
  • N-acyl-l-alpha-amino acid
  • N-acyl-alpha amino acid or derivatives
  • Alpha-amino acid
  • Alpha-amino acid or derivatives
  • L-alpha-amino acid
  • Imidazolyl carboxylic acid derivative
  • Dicarboxylic acid or derivatives
  • Fatty amide
  • N-acyl-amine
  • Fatty acyl
  • Heteroaromatic compound
  • Azole
  • Imidazole
  • Amino acid or derivatives
  • Secondary carboxylic acid amide
  • Carboxamide group
  • Amino acid
  • Azacycle
  • Organoheterocyclic compound
  • Carboxylic acid
  • Primary amine
  • Organic oxygen compound
  • Organic nitrogen compound
  • Organic oxide
  • Primary aliphatic amine
  • Carbonyl group
  • Amine
  • Hydrocarbon derivative
  • Organonitrogen compound
  • Organooxygen compound
  • Aromatic heteromonocyclic compound
Molecular FrameworkAromatic heteromonocyclic compounds
External DescriptorsNot Available
Ontology
StatusExpected but not Quantified
Origin
  • Endogenous
BiofunctionNot Available
ApplicationNot Available
Cellular locationsNot Available
Physical Properties
StateNot Available
Experimental Properties
PropertyValueReference
Melting PointNot AvailableNot Available
Boiling PointNot AvailableNot Available
Water SolubilityNot AvailableNot Available
LogPNot AvailableNot Available
Predicted Properties
PropertyValueSource
logP-3ALOGPS
logP-6.5ChemAxon
logS-1.8ALOGPS
pKa (Strongest Acidic)1.67ChemAxon
pKa (Strongest Basic)9.31ChemAxon
Physiological Charge-1ChemAxon
Hydrogen Acceptor Count7ChemAxon
Hydrogen Donor Count5ChemAxon
Polar Surface Area158.4 ŲChemAxon
Rotatable Bond Count8ChemAxon
Refractivity65.58 m³·mol⁻¹ChemAxon
Polarizability27.4 ųChemAxon
Number of Rings1ChemAxon
BioavailabilityYesChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleYesChemAxon
Spectra
Spectra
Biological Properties
Cellular LocationsNot Available
Biospecimen Locations
  • Placenta
Pathways
Normal Concentrations
BiospecimenStatusValueAgeSexConditionReferenceDetails
PlacentaExpected but not QuantifiedNot QuantifiedNot SpecifiedNot SpecifiedNormal
  • Not Applicable
 details
Abnormal Concentrations
Not Available
HMDB IDHMDB0029151
DrugBank IDNot Available
Phenol Explorer Compound IDNot Available
FooDB IDFDB112147
KNApSAcK IDNot Available
Chemspider ID5380197
KEGG Compound IDNot Available
BioCyc IDNot Available
BiGG IDNot Available
Wikipedia LinkNot Available
METLIN IDNot Available
PubChem Compound7017195
PDB IDNot Available
ChEBI ID133032
References
Synthesis ReferenceNot Available
Material Safety Data Sheet (MSDS)Not Available
General ReferencesNot Available