Stature, PLAG1-related
Phenotype Details
- Phene ID
- 4638
- Name
- Stature, PLAG1-related
- Phene Name
- N/A
- OMIA ID
- 2405
- Species ID
- 9913
- Characterised
- No
- Characterised Year
- N/A
Summary
Utsunomiya et al. 2017: "Using haplotype analysis, we found evidence that the bovine PLAG1 mutation (Q) with major effects on body size, weight and reproduction is a >1,000 years old derived allele that increased rapidly in frequency in Northwestern European B. taurus between the 16th and 18th centuries. Towards the 19th and 20th centuries, Q was introgressed into non-European B. taurus and Bos indicus breeds. These data implicate a major role of Q in recent changes in body size in modern cattle, and represent one of the first examples of a genomic sweep in livestock that was driven by selection on a complex trait."