| Identification |
|---|
| BMDB Protein ID
| BMDBP00008 |
| Secondary Accession Numbers
| None |
| Name
| Ferric-chelate reductase 1 |
| Synonyms
|
Not Available
|
| Gene Name
| FRRS1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in dopamine beta-monooxygenase activity |
| Specific Function
| Ferric-chelate reductases reduce Fe(3+) to Fe(2+) before its transport from the endosome to the cytoplasm. |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 3 |
| Locus
| Not Available |
| SNPs
| FRRS1 |
| Gene Sequence
|
>1776 bp
ATGACAGCTCCTGGATTTACCGTCAGTGCCTTCATCCTTCTGTTGCATGTTAGTTTTGTG
GCTAATTATCCCAGTGGAAAAGTAACAAAGTCATGCGGTGGAATGATTCCTGAGCATGGT
CATACCCCACAGTCTCATCCCGCTCACAACATTTCAGTGAGTCAGAAGACATTCAGGCCA
GGAGATCAAATCAAAGTTACTTTGTCAGGGCCACCATTTAAAGGCTTTCTCTTAGAAGCA
CGTGACGCTGAGAATTTGAGTGGCCCTCCTGTTGGCTCCTTCACACTGATTGACAGTCAC
GTGTCACAGCTTCTGACCTGTGAAGATGTACAGGGATCAGCTGTAAGTCATAGAAGTCCA
TCAAAGAAAACAGAAATCAAGGTCTTTTGGGATGCTCCAAGCGGTGCCCCAAATCACATA
ACCTTCCTAGCCACAGTCGTTGAGAAGTACAAAATCTACTGGGTGAAGATTCCTGGTCCT
GTAATTTCACAACCAAATGTACCTCCTTTTACAACACCTGAAGCTACAATAGCACCCATG
CCAACGGTACCGTCAGTCTCCCATTTAACAAGATCATTCAATGCTTCAGACTGTGGGAAC
AAGAAGTTCTGTATCAGGAGTCCTTTGAACTGTGACCCAGAGAAGGAGCGTGCCTGTGTC
TTATTGTCCTTCACACGAGATGACCAATCAGTGATGGTTGAAATGAGCGGTCCTAGTAAA
GGCTATTTATCCGTGGCATTTTCTCATGACCGATGGATGGGTGATGATGATGCTTATGTG
TGTATTCTTGAAGATCAGATTGTTCACATACAACCTTCCCATTTGACAGGGCGAAGTCAT
CCTATAATGGATTTTGGGGATCCTCTTGAGGACATGGCTTGGAGGTTGGTTGATGGTGTT
ATGCAGTGTTCTTTCAGAAGAAACATTACCCTTCCTGGGGTTAAGAATAGATTTGATCTA
AATGCAAGCTACTACATATTTGTAGCAGATGGTGCAGCTGTTGATGGTCGAATTCATAAG
CATTCTCAGCAACCTTTGATTACATATGAAAAATACAATGTGACAGGCGATCCAAAGAAC
ATAGGAGGATCCCATTCTTTACTCCTTCTGAAGGTTCATGGTGCCTTAATGTTTGTGGCA
TGGATGACCACTGTTAGTGTAGGTGTACTGATTGCCCGGTTCTTCAAACCTGTTTGGTCA
AAGGCTTTATTTGGTGATGCAGCTTGGTTTCAGGTGCATCGAACTCTCATGCTCACTACT
TCTGCCCTCACCTTTATTGCTTTCCTTCTGCCTTTTATTTACAGAGGAGGCTGGAACTGG
CATGCAGGTTATCACCCATACCTTGGTTTTATAGTGATGGTTTTAGCAGTTCTTCAGCTT
CTTTTGGCAGCTTTCAGACCACCTTTACATGACCCAAGAAGGCAAATGTTTAACTGGACT
CATTGGAGTATGGGAACAGCTGCTAGAATAATAGCAGTGGCAGCAATGTTCCTGGGAATG
GATTTGCCAGGACTGAATCTTCCTGGCCCATGGAAAACCTATGCAATGATTGGATTTGTA
GCCTGGCACGTTGGGACAGAGATTATTCTGGAGATACATGCTTACCGACTCTCTAGGAAA
GTTGAAATACTGGATGATGATAGAATTCAGATCCTCCAGTCGTTTACTGCAGCTGAAGCA
GAAGGTTATGTTTTTAAAAAGGTGGTGTTAGCAATTTATGTTTGTGGGAATTTGACTTTT
CTCACTATGTTCTTATCTGCAATCAACCGTCTATGA
|
| Protein Properties |
|---|
| Number of Residues
| 591 |
| Molecular Weight
| 65660.0 |
| Theoretical pI
| 8.47 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
- 6-26
- 372-392
- 416-436
- 445-465
- 490-510
- 514-534
- 568-588
|
| Protein Sequence
|
>Ferric-chelate reductase 1
MTAPGFTVSAFILLLHVSFVANYPSGKVTKSCGGMIPEHGHTPQSHPAHNISVSQKTFRP
GDQIKVTLSGPPFKGFLLEARDAENLSGPPVGSFTLIDSHVSQLLTCEDVQGSAVSHRSP
SKKTEIKVFWDAPSGAPNHITFLATVVEKYKIYWVKIPGPVISQPNVPPFTTPEATIAPM
PTVPSVSHLTRSFNASDCGNKKFCIRSPLNCDPEKERACVLLSFTRDDQSVMVEMSGPSK
GYLSVAFSHDRWMGDDDAYVCILEDQIVHIQPSHLTGRSHPIMDFGDPLEDMAWRLVDGV
MQCSFRRNITLPGVKNRFDLNASYYIFVADGAAVDGRIHKHSQQPLITYEKYNVTGDPKN
IGGSHSLLLLKVHGALMFVAWMTTVSVGVLIARFFKPVWSKALFGDAAWFQVHRTLMLTT
SALTFIAFLLPFIYRGGWNWHAGYHPYLGFIVMVLAVLQLLLAAFRPPLHDPRRQMFNWT
HWSMGTAARIIAVAAMFLGMDLPGLNLPGPWKTYAMIGFVAWHVGTEIILEIHAYRLSRK
VEILDDDRIQILQSFTAAEAEGYVFKKVVLAIYVCGNLTFLTMFLSAINRL
|
| External Links |
|---|
| GenBank ID Protein
| AAI33505.1 |
| UniProtKB/Swiss-Prot ID
| A2VE04 |
| UniProtKB/Swiss-Prot Entry Name
| FRRS1_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC133504 |
| GeneCard ID
| FRRS1 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
