Showing Protein Cytochrome c1, heme protein, mitochondrial (BMDBP00023)
| Identification | |
|---|---|
| BMDB Protein ID | BMDBP00023 |
| Secondary Accession Numbers | None |
| Name | Cytochrome c1, heme protein, mitochondrial |
| Synonyms | Not Available |
| Gene Name | CYC1 |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Energy production and conversion |
| Specific Function | Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c. Cytochrome c1 is a catalytic core subunit containing a c-type heme. It transfers electrons from the [2Fe-2S] iron-sulfur cluster of the Rieske protein to cytochrome c. |
| Pathways | Not Available |
| Reactions | Not Available |
| GO Classification | Not Available |
| Cellular Location | Not Available |
| Gene Properties | |
| Chromosome Location | 14 |
| Locus | Not Available |
| SNPs | CYC1 |
| Gene Sequence |
>978 bp ATGGCGGCGGCGGCGGCTACGCTTCGCGGGGCGATGGTGGGCCCGCGGGGCGCGGGGCTG CCGGGAGCGCGGGCCCGAGGTCTGCTGTGTGGCGCGCGGCCCGGGCAGCTCCCACTACGG ACACCCCAGGCAGTGTCGTTGTCGTCGAAGTCTGGCCTGTCCCGGGGCCGGAAAGTGATT CTGTCAGCGCTGGGCATGCTGGCGGCAGGGGGTGCAGGGCTGGCAGTGGCTCTGCATTCT GCCGTGAGTGCTAGTGACCTGGAGCTGCACCCCCCCAGCTATCCGTGGTCCCACCGTGGC CTCCTCTCCTCCCTGGACCACACCAGCATCCGGAGGGGTTTCCAGGTGTACAAGCAGGTG TGCTCCTCCTGCCACAGCATGGACTATGTGGCCTACCGCCACCTGGTGGGCGTGTGCTAC ACAGAGGATGAAGCCAAGGCGCTGGCTGAGGAGGTGGAGGTTCAGGACGGCCCCAATGAA GATGGGGAGATGTTCATGCGCCCAGGGAAGCTGTCTGACTACTTCCCCAAACCATACCCC AACCCCGAGGCTGCACGTGCAGCCAACAACGGAGCACTGCCCCCTGACCTCAGCTACATC GTGCGAGCTAGGCACGGTGGTGAGGACTACGTCTTTTCCTTGCTCACCGGCTACTGTGAG CCGCCCACTGGGGTGTCGCTGCGAGAAGGCCTCTACTTCAACCCTTATTTTCCTGGCCAG GCCATTGGCATGGCCCCTCCAATCTACAATGAGGTCTTGGAGTTTGATGATGGCACCCCA GCTACCATGTCCCAGGTAGCCAAGGATGTGTGTACCTTCCTGCGCTGGGCAGCTGAACCA GAACACGACCATCGCAAACGCATGGGGCTTAAGATGCTGCTGATGATGGGCTTGCTTCTG CCCCTGGTCTACGCCATGAAGCGGCATAAGTGGTCAGTCCTCAAGAGCCGAAAGCTGGCC TATCGGCCACCCAAGTGA |
| Protein Properties | |
| Number of Residues | 325 |
| Molecular Weight | 35297.0 |
| Theoretical pI | 9.23 |
| Pfam Domain Function | Not Available |
| Signals |
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| Transmembrane Regions |
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| Protein Sequence |
>Cytochrome c1, heme protein, mitochondrial MAAAAATLRGAMVGPRGAGLPGARARGLLCGARPGQLPLRTPQAVSLSSKSGLSRGRKVI LSALGMLAAGGAGLAVALHSAVSASDLELHPPSYPWSHRGLLSSLDHTSIRRGFQVYKQV CSSCHSMDYVAYRHLVGVCYTEDEAKALAEEVEVQDGPNEDGEMFMRPGKLSDYFPKPYP NPEAARAANNGALPPDLSYIVRARHGGEDYVFSLLTGYCEPPTGVSLREGLYFNPYFPGQ AIGMAPPIYNEVLEFDDGTPATMSQVAKDVCTFLRWAAEPEHDHRKRMGLKMLLMMGLLL PLVYAMKRHKWSVLKSRKLAYRPPK |
| External Links | |
| GenBank ID Protein | AAI09918.1 |
| UniProtKB/Swiss-Prot ID | P00125 |
| UniProtKB/Swiss-Prot Entry Name | CY1_BOVIN |
| PDB IDs | |
| GenBank Gene ID | BC109917 |
| GeneCard ID | CYC1 |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| References | |
| General References | Not Available |