| Identification |
|---|
| BMDB Protein ID
| BMDBP00029 |
| Secondary Accession Numbers
| |
| Name
| Guanylate cyclase soluble subunit beta-1 |
| Synonyms
|
Not Available
|
| Gene Name
| GUCY1B1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Signal transduction mechanisms |
| Specific Function
| Mediates responses to nitric oxide (NO) by catalyzing the biosynthesis of the signaling molecule cGMP. |
| Pathways
|
Not Available
|
| Reactions
|
| Guanosine triphosphate → Guanosine 2',3'-cyclic phosphate + Pyrophosphate |
details
|
| Guanosine triphosphate → Cyclic GMP |
details
|
|
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 17 |
| Locus
| Not Available |
| SNPs
| GUCY1B1 |
| Gene Sequence
|
>1860 bp
ATGTATGGATTCGTGAATCACGCGCTGGAGCTGCTGGTGATCCGCAACTACGGCCCTGAG
GTGTGGGAAGACATCAAAAAAGAGGCACAATTAGATGAAGAAGGACAGTTTCTTGTCCGA
ATAATTTATGATGATTCTAAAACATATGATTTGGTTGCTGCTGCAAGCAAGGTCCTCAAT
CTCAACGCTGGAGAAATCCTCCAAATGTTTGGGAAGATGTTCTTCGTCTTCTGTCAAGAA
TCTGGTTATGATACAATCCTGCGCGTCCTGGGATCTAACGTCAGAGAATTTCTGCAGAAC
CTTGATGCTCTGCACGACCACCTTGCTACCATCTACCCAGGCATGCGGGCACCTTCCTTC
CGGTGCACTGATGCGGACAAGGGCAAAGGACTCATCCTGCACTACTACTCAGAGAGAGAA
GGGCTGCAGGATATTGTCATCGGAATCATCAAGACAGTAGCTCAGCAGATACATGGCACT
GAAATTGACATGAAGGTTATTCAACAAAGAAATGAAGAATGTGATCATACTCAATTTTTG
ATTGAAGAAAAAGAGTCAAAAGAAGAGGATTTTTATGAAGATCTTGACAGATTTGAAGAA
AACGGTACCCAGGAATCACGCATCAGCCCATATACGTTCTGCAAAGCCTTTCCCTTTCAC
ATCATATTTGACAGGGATCTTGTGGTCACTCAGTGTGGCAACGCCATCTACAGAGTCCTT
CCCCAGCTCCAGCCTGGGAACTGCAGCCTCCTGTCTGTCTTCTCCCTGGTCCGTCCTCAT
ATTGACATCAGTTTCCATGGAATCCTCTCACACATCAATACAGTCTTCGTGTTGAGAAGC
AAGGAAGGGTTGTTGGATGTAGAGAAATCAGAGTGTGAGGATGAGCTGACGGGCACTGAA
ATCAGCTGCTTACGGCTCAAGGGTCAGATGATCTACTTGCCCGAAGCAGACAGCATACTT
TTCCTGTGCTCACCAAGTGTCATGAACCTGGACGACCTGACCCGGCGAGGGCTGTACCTG
AGTGACATCCCTCTGCACGATGCCACTCGGGACCTCGTGCTCCTGGGAGAGCAGTTCAGA
GAGGAGTACAAGCTGACCCAGGAACTGGAAATCCTCACAGACAGGCTGCAGCTCACGTTA
CGAGCCCTGGAAGATGAAAAGAAAAAGACGGACACGTTGCTGTATTCTGTGCTTCCTCCA
TCTGTGGCCAACGAGCTGAGGCACAAGCGTCCGGTGCCTGCGAAGAGATATGACAACGTG
ACTATCCTCTTCAGCGGCATTGTGGGCTTCAATGCTTTCTGCAGCAAGCACGCGTCTGGG
GAAGGGGCCATGAAGATTGTCAACCTCCTCAATGACCTCTACACTAGATTTGACACTCTG
ACGGACTCCCGGAAAAATCCATTTGTTTATAAGGTGGAGACTGTCGGGGACAAGTACATG
ACAGTGAGCGGGCTGCCGGAGCCATGCATCCACCACGCACGGTCCATCTGCCACCTGGCC
TTGGATATGATGGAGATTGCTGGCCAGGTCCAAGTAGATGGTGAATCTGTTCAGATAACG
ATCGGGATCCACACAGGGGAGGTAGTGACCGGAGTCATAGGACAGAGGATGCCTCGCTAC
TGTCTTTTTGGAAACACTGTCAACCTCACAAGCCGAACAGAAACCACTGGAGAAAAAGGG
AAAATAAATGTGTCTGAATATACATACAGATGTCTCATGACACCAGAAAATTCAGACCCG
CAATTCCATTTGGAGCACAGAGGCCCCGTGTCCATGAAGGGCAAAAAGGAGCCAATGCAA
GTTTGGTTTCTATCCAGAAAAAATACAGGAACAGAGGAAACGGAGCAGGATGAAAACTGA
|
| Protein Properties |
|---|
| Number of Residues
| 619 |
| Molecular Weight
| 70502.0 |
| Theoretical pI
| 4.97 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Guanylate cyclase soluble subunit beta-1
MYGFVNHALELLVIRNYGPEVWEDIKKEAQLDEEGQFLVRIIYDDSKTYDLVAAASKVLN
LNAGEILQMFGKMFFVFCQESGYDTILRVLGSNVREFLQNLDALHDHLATIYPGMRAPSF
RCTDADKGKGLILHYYSEREGLQDIVIGIIKTVAQQIHGTEIDMKVIQQRNEECDHTQFL
IEEKESKEEDFYEDLDRFEENGTQESRISPYTFCKAFPFHIIFDRDLVVTQCGNAIYRVL
PQLQPGNCSLLSVFSLVRPHIDISFHGILSHINTVFVLRSKEGLLDVEKSECEDELTGTE
ISCLRLKGQMIYLPEADSILFLCSPSVMNLDDLTRRGLYLSDIPLHDATRDLVLLGEQFR
EEYKLTQELEILTDRLQLTLRALEDEKKKTDTLLYSVLPPSVANELRHKRPVPAKRYDNV
TILFSGIVGFNAFCSKHASGEGAMKIVNLLNDLYTRFDTLTDSRKNPFVYKVETVGDKYM
TVSGLPEPCIHHARSICHLALDMMEIAGQVQVDGESVQITIGIHTGEVVTGVIGQRMPRY
CLFGNTVNLTSRTETTGEKGKINVSEYTYRCLMTPENSDPQFHLEHRGPVSMKGKKEPMQ
VWFLSRKNTGTEETEQDEN
|
| External Links |
|---|
| GenBank ID Protein
| CAA68739.1 |
| UniProtKB/Swiss-Prot ID
| P16068 |
| UniProtKB/Swiss-Prot Entry Name
| GCYB1_BOVIN |
| PDB IDs
|
|
| GenBank Gene ID
| Y00770 |
| GeneCard ID
| GUCY1B1 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
