Showing Protein Lactoperoxidase (BMDBP00049)
| Identification | |
|---|---|
| BMDB Protein ID | BMDBP00049 |
| Secondary Accession Numbers | None |
| Name | Lactoperoxidase |
| Synonyms | Not Available |
| Gene Name | LPO |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Involved in calcium ion binding |
| Specific Function | Antimicrobial agent which utilizes hydrogen peroxide and thiocyanate (SCN) to generate the antimicrobial substance hypothiocyanous acid (HOSCN). May protect the udder from infection and promote growth in newborn calves. Inhibits growth of the following bacterial species: E.coli, K.pneumoniae, P.aeruginosa, S.sonnei, S.saphrophyticus, S.epidermidis, and S.dysenteriae. |
| Pathways |
|
| Reactions | Not Available |
| GO Classification | Not Available |
| Cellular Location | Not Available |
| Gene Properties | |
| Chromosome Location | 19 |
| Locus | 19q13 |
| SNPs | LPO |
| Gene Sequence |
>2139 bp ATGTGGGTCTGTCTCCAACTTCCAGTCTTTTTGGCTTCCGTGACCTTATTCGAGGTTGCA GCATCTGACACAATTGCACAGGCCGCCAGCACCACCACCATCTCTGATGCTGTGAGTAAG GTCAAGATCCAGGTCAACAAGGCCTTCCTGGATTCCCGGACCAGGCTGAAGACGACCTTG AGCTCTGAGGCACCCACCACCCAACAGCTCTCAGAGTACTTCAAGCACGCAAAGGGCCGG ACCCGCACGGCCATTCGCAACGGGCAGGTGTGGGAGGAGTCCTTAAAGAGGCTGAGGCGG GACACAACCCTGACCAACGTCACAGACCCTAGCCTGGACTTGACTGCACTCTCCTGGGAG GTGGGCTGCGGTGCCCCGGTTCCTCTGGTGAAATGTGATGAAAACAGCCCTTACCGCACC ATCACGGGAGACTGTAATAACAGGAGGAGCCCCGCACTGGGCGCCGCCAACAGGGCGCTG GCGCGCTGGCTGCCGGCGGAGTACGAGGACGGGCTCGCCCTGCCCTTCGGCTGGACGCAG AGGAAGACGCGCAACGGCTTCCGCGTCCCGCTGGCCCGGGAGGTATCCAACAAAATTGTA GGCTACCTGGACGAAGAGGGTGTTCTGGACCAAAACAGGTCCCTGCTCTTCATGCAGTGG GGTCAGATTGTGGACCACGACCTGGACTTCGCCCCGGAAACGGAACTGGGGAGCAACGAG CACTCTAAAACCCAGTGTGAGGAGTACTGTATCCAGGGAGACAACTGCTTCCCCATCATG TTCCCGAAAAATGATCCCAAGTTGAAGACTCAAGGGAAATGCATGCCTTTCTTCCGAGCC GGGTTTGTCTGCCCCACTCCACCTTACCAGTCGTTGGCCCGAGAACAGATCAATGCTGTG ACCTCCTTCCTGGACGCCAGCTTAGTGTACGGCTCTGAGCCCAGTCTGGCCAGCCGTCTC CGGAACCTCAGCAGCCCGCTGGGCCTCATGGCTGTCAACCAAGAAGCCTGGGACCACGGG CTGGCCTACCTGCCCTTTAACAACAAGAAGCCGAGCCCCTGTGAGTTCATCAACACCACC GCCCGCGTGCCCTGTTTCCTGGCGGGAGATTTTCGAGCCTCAGAGCAGATTCTGCTGGCC ACTGCCCACACCCTCCTTCTCCGGGAGCACAACCGGCTGGCCAGAGAACTAAAGAAACTC AACCCTCACTGGAATGGAGAGAAGCTCTACCAGGAAGCCCGGAAAATCCTGGGAGCCTTC ATACAGATCATCACCTTTAGGGACTACCTACCCATTGTGCTAGGTAGTGAGATGCAGAAG TGGATCCCGCCCTACCAAGGCTATAATAACTCTGTGGATCCCCGAATTTCCAATGTCTTC ACCTTTGCCTTCCGCTTTGGCCACATGGAGGTTCCCTCCACTGTGTCCCGCCTGGATGAG AATTACCAGCCATGGGGTCCGGAAGCAGAGCTCCCCCTACACACCCTCTTCTTCAACACC TGGAGGATAATCAAAGACGGTGGAATTGACCCTCTGGTGCGGGGTCTGCTGGCCAAGAAG TCCAAACTGATGAATCAGGATAAAATGGTGACGAGTGAGCTGCGCAACAAGCTTTTCCAG CCCACTCACAAGATCCACGGCTTTGACCTGGCTGCTATCAACTTACAGCGTTGCCGAGAC CATGGGATGCCTGGGTACAACTCCTGGAGGGGCTTCTGTGGCCTCTCACAGCCCAAGACA CTGAAGGGGCTGCAGACTGTGCTGAAGAACAAGATACTGGCTAAGAAGTTAATGGATCTC TATAAGACCCCCGACAACATTGACATCTGGATTGGAGGCAACGCTGAGCCCATGGTAGAA AGGGGCCGGGTGGGGCCACTCCTGGCCTGCCTCCTAGGGAGGCAATTCCAGCAGATACGT GATGGGGACAGGTTCTGGTGGGAGAACCCTGGGGTCTTCACTGAGAAGCAGCGGGACTCT CTACAGAAAGTGTCCTTCTCACGCCTCATCTGTGACAACACCCACATCACGAAGGTCCCG CTGCATGCCTTCCAGGCCAACAACTACCCACATGACTTTGTGGATTGCTCAACCGTTGAT AAGCTGGATCTCTCACCCTGGGCCTCCAGGGAGAATTAG |
| Protein Properties | |
| Number of Residues | 712 |
| Molecular Weight | 80642.0 |
| Theoretical pI | 8.68 |
| Pfam Domain Function | Not Available |
| Signals |
|
| Transmembrane Regions | Not Available |
| Protein Sequence |
>Lactoperoxidase MWVCLQLPVFLASVTLFEVAASDTIAQAASTTTISDAVSKVKIQVNKAFLDSRTRLKTTL SSEAPTTQQLSEYFKHAKGRTRTAIRNGQVWEESLKRLRRDTTLTNVTDPSLDLTALSWE VGCGAPVPLVKCDENSPYRTITGDCNNRRSPALGAANRALARWLPAEYEDGLALPFGWTQ RKTRNGFRVPLAREVSNKIVGYLDEEGVLDQNRSLLFMQWGQIVDHDLDFAPETELGSNE HSKTQCEEYCIQGDNCFPIMFPKNDPKLKTQGKCMPFFRAGFVCPTPPYQSLAREQINAV TSFLDASLVYGSEPSLASRLRNLSSPLGLMAVNQEAWDHGLAYLPFNNKKPSPCEFINTT ARVPCFLAGDFRASEQILLATAHTLLLREHNRLARELKKLNPHWNGEKLYQEARKILGAF IQIITFRDYLPIVLGSEMQKWIPPYQGYNNSVDPRISNVFTFAFRFGHMEVPSTVSRLDE NYQPWGPEAELPLHTLFFNTWRIIKDGGIDPLVRGLLAKKSKLMNQDKMVTSELRNKLFQ PTHKIHGFDLAAINLQRCRDHGMPGYNSWRGFCGLSQPKTLKGLQTVLKNKILAKKLMDL YKTPDNIDIWIGGNAEPMVERGRVGPLLACLLGRQFQQIRDGDRFWWENPGVFTEKQRDS LQKVSFSRLICDNTHITKVPLHAFQANNYPHDFVDCSTVDKLDLSPWASREN |
| External Links | |
| GenBank ID Protein | AAA62714.1 |
| UniProtKB/Swiss-Prot ID | P80025 |
| UniProtKB/Swiss-Prot Entry Name | PERL_BOVIN |
| PDB IDs | |
| GenBank Gene ID | M58150 |
| GeneCard ID | LPO |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| References | |
| General References | Not Available |