| Identification |
|---|
| BMDB Protein ID
| BMDBP00064 |
| Secondary Accession Numbers
| None |
| Name
| Thromboxane-A synthase |
| Synonyms
|
Not Available
|
| Gene Name
| TBXAS1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Secondary metabolites biosynthesis, transport and catabolism |
| Specific Function
| Not Available |
| Pathways
|
- Arachidonic Acid Metabolism
|
| Reactions
|
| Prostaglandin H2 → Thromboxane A2 |
details
|
|
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 4 |
| Locus
| Not Available |
| SNPs
| TBXAS1 |
| Gene Sequence
|
>1602 bp
ATGGAAGTCTTAGGGCTCTTCAGGCTGGAAGTGAGTGGCCCCATGGTGACGGTGGCCCTG
TCCGTGGTCTTCTTGGCCCTCCTGAAATGGTACTCCACATCAGCGTTTTCAAGACTAGAG
AAGTTGGGCATCAGACATCCCAAGCCTTCTCCTTTTATTGGAAACTTAGCGTTTTTCCGC
CAGGGTTTCTGGGAAAGCCACATGGAGCTCAGAAAGCAATATGGACCTCTGAGTGGGTAC
TATCTTGGTCGTCTGATGTTTATTGTTATCTCTGAGCCAGACATGATTGAGCAGGTGTTG
GTTGAGAAGTTCAGTAACTTTACCAACAGAATGGCAACGGGTTTGGAGCCCAAACCAGTG
GCCGACAGTGTCCTGTTCTTACGTGACAAAAGATGGGAAGAGGTCAGAAGTGTCCTGACT
GTGGCTTTCAGTCCTGAAAAACTGAGTGAGATGACTCCTTTAATCAGCCGGGCCTGCGAT
GTGCTTCTGGCTCACCTAGAGCGTCACGCACAGTCTGGGGAGGCTTTTGACATCCAGAGG
ACCTACTGCTGCTACACCACAGATGTGGTGGCCAGTGTTGCCTTTGGCACCGAAGTGAAC
TCCCAGGAGGCTCCTGAGCACCCCTTCGTGGAGCACTGCAGGCGCTTCTTTGCATCCTCC
ATCCCCAAACCTCTCCTGGTTTTACTCTTATCATTTCCATCCATAATGGTCCCACTGGCC
CGGATTTTGCCCAATAAGAACCGAGATGAACTGAATGGCTTTTTTAACAAACTCATTAGG
AATGTGATTGCCTTGCGGGACCAGCAAGCAGCCGAAGAGAGGAGGAGAGATTTCCTCCAA
ATGGTCCAGGATGTGCGCCATTCTGCTGCCACAGTGGGCGTGGAGAAATTTGACATCGTC
CGTCAGGTCTTTTCTGCCACCAAATGCCCAGCAAACCCTCCCCGGCGACACTCACCCAGA
CCCCTGTCCAAGCCTTTGAGTGTGGATGAGGTGGTGGGCCAGGCCTTCATCTTCCTCATC
GCTGGCTACGAGATTGTCACCAACACTCTCTCTTTCGCCACCTACCTCCTGGCCACCAAC
CCTGAGTGCCAAGAGAAGCTTCTGGAAGAGGTGGACTGTTTCAGCAAGGAACATCTGGCC
CCTGAGTACTGCAGCCTCCAGGAAGGTCTGCCCTACTTGGACATGGTGATTAAAGAGACC
TTGAGGATGTACCCACCGGCTTTCAGGTTCACGCGGGTGGCGGCACAGGACTGCGAGGTG
CTGGGCCAGCGCATCCCCGCAGGCGCTGTGCTAGAGACGGCCGTGGGCGCTCTGCACTAC
GACCCCGAGCACTGGCCGAACCCCGAGAACTTCAACCCCGAGAGGTTCACTGCCGAGGCG
CAACAACGCCGGCGGCCCTACACGTACCTGCCGTTTGGGGCGGGCCCCCGGAGCTGCCTC
GGGGTTCGGCTGGGGCTCCTGGAGCTCAAGCTGACGCTGCTCCACATCCTGCGCAAGTTC
CGGTTCGAAGCCTGTCCCGAGACGCAGGTACCACTGCAGCTAGAATCCAAATCTGCCCTA
GGTCCAAAAAATGGCGTCTACATCAGAATCGTCTCTCGCTGA
|
| Protein Properties |
|---|
| Number of Residues
| 533 |
| Molecular Weight
| 60539.0 |
| Theoretical pI
| 8.06 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
- 11-31
- 76-96
- 224-244
- 336-356
|
| Protein Sequence
|
>Thromboxane-A synthase
MEVLGLFRLEVSGPMVTVALSVVFLALLKWYSTSAFSRLEKLGIRHPKPSPFIGNLAFFR
QGFWESHMELRKQYGPLSGYYLGRLMFIVISEPDMIEQVLVEKFSNFTNRMATGLEPKPV
ADSVLFLRDKRWEEVRSVLTVAFSPEKLSEMTPLISRACDVLLAHLERHAQSGEAFDIQR
TYCCYTTDVVASVAFGTEVNSQEAPEHPFVEHCRRFFASSIPKPLLVLLLSFPSIMVPLA
RILPNKNRDELNGFFNKLIRNVIALRDQQAAEERRRDFLQMVQDVRHSAATVGVEKFDIV
RQVFSATKCPANPPRRHSPRPLSKPLSVDEVVGQAFIFLIAGYEIVTNTLSFATYLLATN
PECQEKLLEEVDCFSKEHLAPEYCSLQEGLPYLDMVIKETLRMYPPAFRFTRVAAQDCEV
LGQRIPAGAVLETAVGALHYDPEHWPNPENFNPERFTAEAQQRRRPYTYLPFGAGPRSCL
GVRLGLLELKLTLLHILRKFRFEACPETQVPLQLESKSALGPKNGVYIRIVSR
|
| External Links |
|---|
| GenBank ID Protein
| AAI12648.1 |
| UniProtKB/Swiss-Prot ID
| Q2KIG5 |
| UniProtKB/Swiss-Prot Entry Name
| THAS_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC112647 |
| GeneCard ID
| TBXAS1 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
