| Identification |
|---|
| BMDB Protein ID
| BMDBP00066 |
| Secondary Accession Numbers
| None |
| Name
| Cytochrome b5 reductase 4 |
| Synonyms
|
Not Available
|
| Gene Name
| CYB5R4 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Coenzyme transport and metabolism |
| Specific Function
| NADH-cytochrome b5 reductase involved in endoplasmic reticulum stress response pathway. Plays a critical role in protecting pancreatic beta-cells against oxidant stress, possibly by protecting the cell from excess buildup of reactive oxygen species (ROS) (By similarity). |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 9 |
| Locus
| Not Available |
| SNPs
| CYB5R4 |
| Gene Sequence
|
>1563 bp
ATGCTGAACGTCCCTTCCCAGTCTTTCCCGGGCCCCAGCTCGCAGCAGCGCGTCGCCTCC
GGGGGGCGTAGCAAGGTCCCTCTGAAACAGGGCAGAAGTCTCATGGATTGGATTCGACTG
ACCAAAAGTGGAAAGGACCTAACGGGATTAAAAGGCAGATTAATTGAAGTAACTGAAGAA
GAACTTAAAAAACACAACAAAAAAGATGACTGTTGGATATGCATAAGAGGCTTTGTTTAT
AATGTCAGCCCATATATGGAGTATCATCCTGGCGGAGAAGATGAACTTATGAGAGCAGCA
GGATCAGATGGCACTGACCTTTTTGATCAGGTTCATCGTTGGGTCAACTATGAATCCATG
CTGAAAGAATGCCTGGTGGGCAGGATGGCCATGAAACCTGCTCTTCCTAAAGACTATCAT
GAGGAAAAGAAAGTCTTAAATGGCATGCTTCCTCAGAGCCAAGTGACAGATACACTTGCC
AAAGAAGGTCCTAGTTCTCCAAGCTATGACTGGTTCCAAACAGACTCTTTAGTCACCATC
GTCATATATACTAAACAGAAGGATATCAACTTAGATTCAGTAATAGTTGATCATCGGGAT
GATTCCTTTAGAGCCGAGACAGTTATCAAGGATTATTCATACCTTGTACATGTTGCCCTG
AGTCATGAGATTCAAGAAGATTTTTCTGTGCTAGTTGTTGAGAATGTGGGAAAAATAGAG
ATCGTCCTGAAGAAAAAAGAGAATACTTCTTGGAAATGCCTTGGTCATCCCCAGGAGAAT
CATAATTCATTTATTCCAAAGAAAGATACAGGTTTGTTCTACAGAAAATGCCAGTTAGTT
TCCAAGGAAGATGTGACTCATGATACGAAGCTGTTCTGCTTAATGCTGCCACCAAGCACA
CATCTTGAGGTGCCAGTTGGGCAACACGTTTACCTCAGGCTACCTATTACAGGTACTGAA
ATTGTGAAGCCATATACACCTGTATGTGATTCCTTATTCTCAGAGTTCAAGGAACCAGTT
CTTCCCAACAATATATACATCTACTTTTTGATCAAAATCTACCCTGCTGGATTCTTCACA
CCAGAGCTTGATCAGCTTCAGATTGGAGATTATGTTTCTGTAAGCAATCCTGAGGGCAAT
TTTATAATATCCCAGCTCCAAGAATTGGAAGATCTCTTTTTATTGGCAGCAGGAACAGGC
TTCACACCAATGGTTAAAGTACTGAATTATGCTTTGACTAATATACCCAGTCTCAGGAAA
GTGAAGCTGATGTTCTTCAATAAAACAGAGGATGACATAATTTGGAGAAGCCAGTTGGAG
AAATTAGCATTTAAGGATAAAAGATTTGAGGTTGAATTTGTCCTCTCAGCACCTACTTCT
GAATGGAGTGGCAAACAGGGATACATTTCACCAGCTCTGCTCTCTGAATTTTTGAAAAGA
AGATCAGACACATCCAAAGTCCTCATCTGCCTTTGTGGACCAACGCCATTCACAGAACAA
GGAATGAAGATGCTGCATGATCTGAACTTTTCCAAAGATGAGATCCATAGTTTTACAGCA
TAA
|
| Protein Properties |
|---|
| Number of Residues
| 520 |
| Molecular Weight
| 59274.0 |
| Theoretical pI
| 6.51 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Cytochrome b5 reductase 4
MLNVPSQSFPGPSSQQRVASGGRSKVPLKQGRSLMDWIRLTKSGKDLTGLKGRLIEVTEE
ELKKHNKKDDCWICIRGFVYNVSPYMEYHPGGEDELMRAAGSDGTDLFDQVHRWVNYESM
LKECLVGRMAMKPALPKDYHEEKKVLNGMLPQSQVTDTLAKEGPSSPSYDWFQTDSLVTI
VIYTKQKDINLDSVIVDHRDDSFRAETVIKDYSYLVHVALSHEIQEDFSVLVVENVGKIE
IVLKKKENTSWKCLGHPQENHNSFIPKKDTGLFYRKCQLVSKEDVTHDTKLFCLMLPPST
HLEVPVGQHVYLRLPITGTEIVKPYTPVCDSLFSEFKEPVLPNNIYIYFLIKIYPAGFFT
PELDQLQIGDYVSVSNPEGNFIISQLQELEDLFLLAAGTGFTPMVKVLNYALTNIPSLRK
VKLMFFNKTEDDIIWRSQLEKLAFKDKRFEVEFVLSAPTSEWSGKQGYISPALLSEFLKR
RSDTSKVLICLCGPTPFTEQGMKMLHDLNFSKDEIHSFTA
|
| External Links |
|---|
| GenBank ID Protein
| AAI09570.1 |
| UniProtKB/Swiss-Prot ID
| Q32LH7 |
| UniProtKB/Swiss-Prot Entry Name
| NB5R4_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC109569 |
| GeneCard ID
| CYB5R4 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
