Showing Protein Cytochrome b5 reductase 4 (BMDBP00066)
| Identification | |
|---|---|
| BMDB Protein ID | BMDBP00066 |
| Secondary Accession Numbers | None |
| Name | Cytochrome b5 reductase 4 |
| Synonyms | Not Available |
| Gene Name | CYB5R4 |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Coenzyme transport and metabolism |
| Specific Function | NADH-cytochrome b5 reductase involved in endoplasmic reticulum stress response pathway. Plays a critical role in protecting pancreatic beta-cells against oxidant stress, possibly by protecting the cell from excess buildup of reactive oxygen species (ROS) (By similarity). |
| Pathways | Not Available |
| Reactions | Not Available |
| GO Classification | Not Available |
| Cellular Location | Not Available |
| Gene Properties | |
| Chromosome Location | 9 |
| Locus | Not Available |
| SNPs | CYB5R4 |
| Gene Sequence |
>1563 bp ATGCTGAACGTCCCTTCCCAGTCTTTCCCGGGCCCCAGCTCGCAGCAGCGCGTCGCCTCC GGGGGGCGTAGCAAGGTCCCTCTGAAACAGGGCAGAAGTCTCATGGATTGGATTCGACTG ACCAAAAGTGGAAAGGACCTAACGGGATTAAAAGGCAGATTAATTGAAGTAACTGAAGAA GAACTTAAAAAACACAACAAAAAAGATGACTGTTGGATATGCATAAGAGGCTTTGTTTAT AATGTCAGCCCATATATGGAGTATCATCCTGGCGGAGAAGATGAACTTATGAGAGCAGCA GGATCAGATGGCACTGACCTTTTTGATCAGGTTCATCGTTGGGTCAACTATGAATCCATG CTGAAAGAATGCCTGGTGGGCAGGATGGCCATGAAACCTGCTCTTCCTAAAGACTATCAT GAGGAAAAGAAAGTCTTAAATGGCATGCTTCCTCAGAGCCAAGTGACAGATACACTTGCC AAAGAAGGTCCTAGTTCTCCAAGCTATGACTGGTTCCAAACAGACTCTTTAGTCACCATC GTCATATATACTAAACAGAAGGATATCAACTTAGATTCAGTAATAGTTGATCATCGGGAT GATTCCTTTAGAGCCGAGACAGTTATCAAGGATTATTCATACCTTGTACATGTTGCCCTG AGTCATGAGATTCAAGAAGATTTTTCTGTGCTAGTTGTTGAGAATGTGGGAAAAATAGAG ATCGTCCTGAAGAAAAAAGAGAATACTTCTTGGAAATGCCTTGGTCATCCCCAGGAGAAT CATAATTCATTTATTCCAAAGAAAGATACAGGTTTGTTCTACAGAAAATGCCAGTTAGTT TCCAAGGAAGATGTGACTCATGATACGAAGCTGTTCTGCTTAATGCTGCCACCAAGCACA CATCTTGAGGTGCCAGTTGGGCAACACGTTTACCTCAGGCTACCTATTACAGGTACTGAA ATTGTGAAGCCATATACACCTGTATGTGATTCCTTATTCTCAGAGTTCAAGGAACCAGTT CTTCCCAACAATATATACATCTACTTTTTGATCAAAATCTACCCTGCTGGATTCTTCACA CCAGAGCTTGATCAGCTTCAGATTGGAGATTATGTTTCTGTAAGCAATCCTGAGGGCAAT TTTATAATATCCCAGCTCCAAGAATTGGAAGATCTCTTTTTATTGGCAGCAGGAACAGGC TTCACACCAATGGTTAAAGTACTGAATTATGCTTTGACTAATATACCCAGTCTCAGGAAA GTGAAGCTGATGTTCTTCAATAAAACAGAGGATGACATAATTTGGAGAAGCCAGTTGGAG AAATTAGCATTTAAGGATAAAAGATTTGAGGTTGAATTTGTCCTCTCAGCACCTACTTCT GAATGGAGTGGCAAACAGGGATACATTTCACCAGCTCTGCTCTCTGAATTTTTGAAAAGA AGATCAGACACATCCAAAGTCCTCATCTGCCTTTGTGGACCAACGCCATTCACAGAACAA GGAATGAAGATGCTGCATGATCTGAACTTTTCCAAAGATGAGATCCATAGTTTTACAGCA TAA |
| Protein Properties | |
| Number of Residues | 520 |
| Molecular Weight | 59274.0 |
| Theoretical pI | 6.51 |
| Pfam Domain Function | Not Available |
| Signals |
|
| Transmembrane Regions | Not Available |
| Protein Sequence |
>Cytochrome b5 reductase 4 MLNVPSQSFPGPSSQQRVASGGRSKVPLKQGRSLMDWIRLTKSGKDLTGLKGRLIEVTEE ELKKHNKKDDCWICIRGFVYNVSPYMEYHPGGEDELMRAAGSDGTDLFDQVHRWVNYESM LKECLVGRMAMKPALPKDYHEEKKVLNGMLPQSQVTDTLAKEGPSSPSYDWFQTDSLVTI VIYTKQKDINLDSVIVDHRDDSFRAETVIKDYSYLVHVALSHEIQEDFSVLVVENVGKIE IVLKKKENTSWKCLGHPQENHNSFIPKKDTGLFYRKCQLVSKEDVTHDTKLFCLMLPPST HLEVPVGQHVYLRLPITGTEIVKPYTPVCDSLFSEFKEPVLPNNIYIYFLIKIYPAGFFT PELDQLQIGDYVSVSNPEGNFIISQLQELEDLFLLAAGTGFTPMVKVLNYALTNIPSLRK VKLMFFNKTEDDIIWRSQLEKLAFKDKRFEVEFVLSAPTSEWSGKQGYISPALLSEFLKR RSDTSKVLICLCGPTPFTEQGMKMLHDLNFSKDEIHSFTA |
| External Links | |
| GenBank ID Protein | AAI09570.1 |
| UniProtKB/Swiss-Prot ID | Q32LH7 |
| UniProtKB/Swiss-Prot Entry Name | NB5R4_BOVIN |
| PDB IDs | Not Available |
| GenBank Gene ID | BC109569 |
| GeneCard ID | CYB5R4 |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| References | |
| General References | Not Available |