Showing Protein 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 (BMDBP00072)
| Identification | |||||
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| BMDB Protein ID | BMDBP00072 | ||||
| Secondary Accession Numbers | None | ||||
| Name | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 | ||||
| Synonyms | Not Available | ||||
| Gene Name | PLCB1 | ||||
| Protein Type | Enzyme | ||||
| Biological Properties | |||||
| General Function | Cell cycle control, cell division, chromosome partitioning | ||||
| Specific Function | The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. | ||||
| Pathways |
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| Reactions |
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| GO Classification | Not Available | ||||
| Cellular Location | Not Available | ||||
| Gene Properties | |||||
| Chromosome Location | 13 | ||||
| Locus | Not Available | ||||
| SNPs | PLCB1 | ||||
| Gene Sequence |
>3651 bp ATGGCCGGGGCACAGCCTGGAGTGCACGCGCTGCAACTCAAGCCGGTGTGCGTGTCCGAC AGCCTCAAGAAGGGCACCAAATTCGTCAAGTGGGAGGATGACTCCACTGTTGTCACTCCG ATTATTTTGAGGACTGACCCTCAGGGATTTTTCTTTTACTGGACAGATCAAAACAAGGAG ACGGAGCTGTTAGATCTCAGCCTTGTCAAAGACGCCAGATGTGGGAAACATGCCAAGGCG CCCAAGGACCCTAAATTACGTGAACTTCTGGATGTGGGGAACATTGGGCGCCTGGAACAT CGCATGATCACAGTGGTGTATGGGCCTGACTTAGTGAACATCTCCCATTTGAACCTCGTG GCTTTCCAAGAAGAAGTGGCCAAGGAATGGACAAATGAGGTTTTCAGTTTGGCAACAAAC CTGCTGGCCCAAAACATGTCCAGGGATGCATTTCTGGAAAAGGCGTATACTAAGCTTAAG CTGCAAGTCACTCCAGAAGGACGCATTCCTCTCAAAAACATATACCGCCTGTTCTCAGCA GACCGGAAGCGAGTCGAGACAGCTTTAGAGGCTTGTAGTCTTCCATCTTCAAGGAATGAT TCGATACCTCAAGAAGATTTCACTCCTGAAGTGTACAGAGTTTTCCTGAACAACCTTTGT CCTCGACCTGAAATTGATAACATCTTTTCCGAATTTGGTGCCAAAAGCAAACCATACCTT ACAGTTGATCAGATGATGGATTTTATCAACCTCAAGCAGCGAGATCCCCGGCTAAATGAA ATACTTTACCCACCTTTAAAGCAAGAGCAAGTCCAAGTGTTGATTGAGAAGTATGAACCT AACAACAGCCTCGCCAAAAAAGGACAGATATCAGTGGATGGATTTATGCGCTATCTGAGT GGAGAAGAAAATGGAGTCGTTTCACCTGAGAAACTGGATTTGAATGAAGATATGTCTCAG CCCCTTTCTCACTATTTCATTAATTCCTCACACAACACCTACCTCACAGCTGGCCAGCTG GCTGGAAACTCCTCCGTTGAGATGTATCGCCAAGTGCTCCTGTCTGGTTGTCGCTGTGTG GAGCTGGACTGCTGGAAGGGACGAACTGCAGAAGAGGAGCCAGTCATCACCCATGGGTTC ACCATGACCACAGAAATATCCTTCAAGGAAGTGATTGAAGCCATTGCTGAATGTGCATTT AAGACTTCACCTTTTCCAATTCTGCTTTCATTTGAGAACCATGTGGACTCGCCGAAGCAG CAAGCCAAGATGGCGGAGTACTGCAGACTCATCTTCGGCGACGCCCTCCTCATGGAGCCG CTGGACAAGTACCCGTTGGAATCTGGAGTTCCCCTTCCAAGTCCTATGGATTTAATGTAC AAAATTTTGGTGAAAAATAAGAAGAAATCACACAAGTCGTCAGAAGGAAGTGGCAAGAAG AAGCTCTCAGAACAAGCTTCCAACACGTACAGCGACTCCTCCAGTGTGTTTGAGCCCTCG TCCCCAGGAGCCGGAGAAGCTGATACAGAGAGTGACGATGATGACGATGATGATGACTGT AAAAAGTCTTCAATGGATGAGGGGACCGCAGGGAGCGAGGCCATGGCCACAGAAGAGATG TCTAATCTGGTGAACTATATCCAGCCAGTCAAGTTCGAGTCATTTGAAATTTCAAAAAAA AGAAATAGAAGCTTCGAGATGTCTTCCTTTGTGGAAACCAAAGGTCTTGAGCAACTTACA AAGTCTCCGGTGGAATTTGTAGAATATAACAAAATGCAGCTTAGCAGGATATATCCAAAG GGAACACGCGTGGATTCATCTAACTATATGCCTCAGCTCTTCTGGAATGCAGGCTGCCAA ATGGTTGCTCTTAATTTCCAAACAGTGGACCTGGCTATGCAGATAAACATGGGGATGTAT GAATATAATGGGAAGAGTGGCTACAGGCTGAAGCCGGAGTTCATGAGGAGACCTGACAAG CACTTTGATCCATTCACAGAAGGCATCGTGGACGGCATAGTGGCCAACACTTTATCTGTT AAGATTATTTCAGGTCAGTTTCTCTCTGATAAGAAAGTCGGGACTTATGTGGAAGTGGAT ATGTTTGGTTTGCCTGTGGACACAAGGAGGAAGGCATTTAAGACCAAAACATCACAAGGA AACGCTGTAAATCCCATCTGGGAAGAAGAACCCATTGTATTCAAAAAGGTGGTCCTTCCT TCGCTAGCCTGTTTGAGGATAGCAGTTTATGAAGAAGGAGGTAAATTTATTGGTCACCGA ATCTTGCCAGTACAAGCAATTCGGCCAGGCTATCACTACATCTGTCTGAGGAATGAGAGG AACCAGCCTCTCATGCTGCCAGCGCTCTTTGTCTACATAGAGGTGAAGGACTATGTCCCA GACACATATGCAGATGTGATTGAAGCTTTGTCAAATCCAATCCGATATGTGAATCTGATG GAGCAGAGAGCTAAACAACTGGCTGCTTTGACACTGGAAGATGAAGAAGAAGTGAAGAAA GAGGCTGATCCTGGGGAAACACCATCAGAAGCTCCGAGTGAAGCCAGGCCAACTCCAGCA GAAAACGGGGTGAATCACACAACGTCCCTGACACCCAAACCACCCTCCCAGGCTCTGCAC AGCCAGCCAGCTCCAGGTTCTGTAAAGGCACCTGCCAAAACAGAAGATCTTATTCAGAGT GTTTTAACAGAAGTAGAAGCGCAGACGATTGAAGAGCTAAAGCAGCAGAAGTCGTTTGTG AAACTTCAAAAGAAGCACTACAAGGAAATGAAGGACCTGGTTAAGAGACACCACAAGAAA ACCACCGACCTCATCAAAGAGCACACTACAAAATACAATGAAATCCAGAATGACTACTTG AGAAGGAGAGCAGCTCTGGAAAAGACAGCCAAAAAGGACAATAAGAAAAAATCAGAACCC AGTAGCCCTGACCACGTCTCATCAACAATTGAGCAAGACCTTGCTGCCCTGGATGCCGAG ATGACCCAAAAGTTAGTAGATCTGAAGGACAAACAGCAGCAGCAGCTGCTTAATCTTCGA CAAGAGCAATACTATAGCGAAAAATACCAGAAACGAGAACACATTAAACTGCTTATTCAA AAATTGACTGATGTTGCTGAAGAATGTCAGAATAATCAGTTAAAGAAGCTCAAAGAAATC TGTGAGAAAGAGAAGAAGGAATTAAAGAAGAAAATGGATAAAAAGAGGCAGGAGAAGATA ACAGAAGCAAAATCCAAAGACAAAAGCCAGATGGAGGAGGAAAAGACAGAGATGATCCGG TCATACATCCAGGAGGTGGTGCAGTACATCAAGAGGTTAGAAGAGGCGCAAAGTAAACGG CAAGAAAAACTCGTAGAGAAACACAAAGAAATCCGCCAGCAGATCCTGGATGAAAAGCCC AAGCTACAGGTGGAACTGGAGCAGGAATACCAAGACAAGTTCAAAAGGCTGCCCCTGGAG ATTTTGGAATTTGTGCAGGAAGCCATGAAAGGGAAGATTAGTGAAGACAGCAATCACAGC TCTGCCCCTCCCCTGATGACCTCAGACTCTGGAAAACTAAACCAGAAGCCTCCTTCCAGT GAAGAATTGGAAGGAGAAAACCCAGGAAAAGAGTTTGATACCCCTCTGTGA |
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| Protein Properties | |||||
| Number of Residues | 1216 | ||||
| Molecular Weight | 138715.0 | ||||
| Theoretical pI | 6.05 | ||||
| Pfam Domain Function | Not Available | ||||
| Signals |
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| Transmembrane Regions | Not Available | ||||
| Protein Sequence |
>1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1 MAGAQPGVHALQLKPVCVSDSLKKGTKFVKWEDDSTVVTPIILRTDPQGFFFYWTDQNKE TELLDLSLVKDARCGKHAKAPKDPKLRELLDVGNIGRLEHRMITVVYGPDLVNISHLNLV AFQEEVAKEWTNEVFSLATNLLAQNMSRDAFLEKAYTKLKLQVTPEGRIPLKNIYRLFSA DRKRVETALEACSLPSSRNDSIPQEDFTPEVYRVFLNNLCPRPEIDNIFSEFGAKSKPYL TVDQMMDFINLKQRDPRLNEILYPPLKQEQVQVLIEKYEPNNSLAKKGQISVDGFMRYLS GEENGVVSPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLLSGCRCV ELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENHVDSPKQ QAKMAEYCRLIFGDALLMEPLDKYPLESGVPLPSPMDLMYKILVKNKKKSHKSSEGSGKK KLSEQASNTYSDSSSVFEPSSPGAGEADTESDDDDDDDDCKKSSMDEGTAGSEAMATEEM SNLVNYIQPVKFESFEISKKRNRSFEMSSFVETKGLEQLTKSPVEFVEYNKMQLSRIYPK GTRVDSSNYMPQLFWNAGCQMVALNFQTVDLAMQINMGMYEYNGKSGYRLKPEFMRRPDK HFDPFTEGIVDGIVANTLSVKIISGQFLSDKKVGTYVEVDMFGLPVDTRRKAFKTKTSQG NAVNPIWEEEPIVFKKVVLPSLACLRIAVYEEGGKFIGHRILPVQAIRPGYHYICLRNER NQPLMLPALFVYIEVKDYVPDTYADVIEALSNPIRYVNLMEQRAKQLAALTLEDEEEVKK EADPGETPSEAPSEARPTPAENGVNHTTSLTPKPPSQALHSQPAPGSVKAPAKTEDLIQS VLTEVEAQTIEELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTDLIKEHTTKYNEIQNDYL RRRAALEKTAKKDNKKKSEPSSPDHVSSTIEQDLAALDAEMTQKLVDLKDKQQQQLLNLR QEQYYSEKYQKREHIKLLIQKLTDVAEECQNNQLKKLKEICEKEKKELKKKMDKKRQEKI TEAKSKDKSQMEEEKTEMIRSYIQEVVQYIKRLEEAQSKRQEKLVEKHKEIRQQILDEKP KLQVELEQEYQDKFKRLPLEILEFVQEAMKGKISEDSNHSSAPPLMTSDSGKLNQKPPSS EELEGENPGKEFDTPL |
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| External Links | |||||
| GenBank ID Protein | AAA30702.1 | ||||
| UniProtKB/Swiss-Prot ID | P10894 | ||||
| UniProtKB/Swiss-Prot Entry Name | PLCB1_BOVIN | ||||
| PDB IDs | Not Available | ||||
| GenBank Gene ID | J03137 | ||||
| GeneCard ID | PLCB1 | ||||
| GenAtlas ID | Not Available | ||||
| HGNC ID | Not Available | ||||
| References | |||||
| General References | Not Available | ||||