Showing Protein 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 (BMDBP00075)
| Identification | |
|---|---|
| BMDB Protein ID | BMDBP00075 |
| Secondary Accession Numbers |
|
| Name | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 |
| Synonyms | Not Available |
| Gene Name | PLCD1 |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Involved in calcium ion binding |
| Specific Function | The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. Essential for trophoblast and placental development. |
| Pathways | Not Available |
| Reactions | Not Available |
| GO Classification | Not Available |
| Cellular Location | Not Available |
| Gene Properties | |
| Chromosome Location | 22 |
| Locus | Not Available |
| SNPs | PLCD1 |
| Gene Sequence |
>2271 bp ATGGACTCGGGCCGGGACTTCCTGACCCTGCACGGCCTACAGGATGACAAGGACCTACAG GCACTGCTGAAGGGCGGCCAACTCTTGAAGGTGAAGTCCAACTCATGGCGGAGAGAACGC TTCTACAAGCTGCAGGAGGACTGCAAGACCATCTGGCAGGAGTCCCGCAAGGTCATGAGG ACCCCGGAATCCCAGCTGTTCTCCATCGAGGACATCCAGGAGGTGCGGATGGGGCACCGC ACAGAGGGCCTGGAGAAGTTTGCTCGGGATGTGCCTGAGAATCGCTGCTTCTCCATAGTC TTCAAGGACCAGCGCAATACTCTAGACCTCATTGCCCCATCACCAGCCGATGCCCAGCAC TGGGTGCAGGGCCTGGGCAAGATCATCCACCACTCGGGCTCCATGGACCAGCAGCAGAAG CTGCGACACTGGATTCATTCCTGCTTGCGAAAAGCTGACAAAAACAAGGACAACAAGATG AGCTTCAAAGAGCTACAAAACTTTCTGAAGGAGCTCAACATCCAGGTGGACGACAGCTAT GCCCGAAAGATCTTCAAGGAATGTGACCACTCTCAGACAGACTCCCTGGAGGATGAGGAG ATAGAGACCTTCTACAAGATACTGACCCAGAGGAAGGAGATCGACCGCACCTTCGAGGAG GCCACGGGCTCCAAGGAGACCCTGTCGGTGGATCAGTTGGTGACCTTCTTGCAGCACCAG CAGCGGGAGGAGGAGGCGGGGCCTGCACTGGCTCTCTCCCTCATTGAGCGCTACGAACCC AGTGAGACGGCCAAGGCGCAGCGTCAGATGACCAAGGACGGCTTTCTTATGTACCTGCTC TCGGCTGACGGCAGCGCCTTCGACCTGGCGCACCGGCGCGTCTACCAGGACATGGACCAG CCGCTCAGCCACTACCTGGTGTCGTCCTCGCACAACACCTACCTGCTGGAAGACCAGCTC ACGGGTCCCAGCAGCACAGAAGCCTACATCCGGGCGCTGTGCAAAGGCTGCCGCTGCCTG GAGCTCGACTGCTGGGATGGGCCCAACCAGGAGCCGATCATCTATCATGGCTACACCTTC ACCTCCAAGATCCTCTTCTGCGACGTGGTCAGGGCCATCCGGGACTACGCCTTCAAGGCA TCCCCCTACCCCGTCATCCTGTCCTTGGAGAACCACTGCAGCCTGGAACAGCAGCGTGTG ATGGCGCGACACCTGCGCACCCTCCTGGGGCCCATGCTGTTGGATCGGCCATTGGACGGG GTCGTCACCAGCCTGCCTTCCCCTGAGCAACTGAGGGGGAAGATCTTGCTGAAGGGGAAG AAGCTTGGGGGGCTCTTCCCGCCTGGAGGAGAAGGTGGCCCAGAGGCCACTGTGGTGTCA GACGAGGATGAGGCTGCTGAGATGGAGGACGAGGCGGTGAGGAGCCAAGTGCAGCACAAG TCCAAGGAGGACAAGCTCAGGCTAGCGAAGGAACTCTCCGACATGGTCATTTACTGCAAG AGTGTCCACTTTCGGGGCTTCCCCAGCTCTGGCACCTCTGGACAGGCTTTCTATGAGATG TCATCCTTCTCTGAGAACCGCGCCCTCCGACTGCTCCAAGAATCAGGAAACAGCTTTGTC CGCCACAACGTGAATCACCTGAGCAGGATCTACCCCGCTGGGTGGAGAACGGACTCTTCC AACTACAGCCCCGTGGAGATGTGGAATGGGGGCTGCCAGATCGTGGCCCTGAACTTCCAG ACTCCTGGGTCAGAGATGGATGTGTACCAGGGCCGCTTCCTGGACAATGGGGCCTGTGGG TACGTGCTGAAGCCTGCCTTCCTGCGAGACCCCAACTCTACCTTCAACTCCCGTGCCCTG GCCCACGGGCCCTGGTGGACTCCGAAACGACTCAATGTCAGGGTCATCTCAGGGCAGCAG CTGCCAAAAGTCAACAAGAATAAGAATTCAATCGTGGACCCCAAGGTGACAGTGGAGATC CATGGCGTGAGCCGGGACGTGGCCAGCCGCCAGACCGCTGTGGTCACCAATAACGGTTTC AATCCGTGGTGGGACACAGAGTTGGAGTTTGAGGTGGCTGTGCCTGAGCTTGCCCTTGTG CGCTTTGTGGTGGAGGACTACGATGCCTCCTCCAAGAACGACTTCATTGGCCAGAGCACC ATCCCCTTGAAAAGCCTCAAGCAGGGATACCGACACATCCACCTCCTCTCCAAGAACGGG GACCAGCACCCGTCTGCCACCCTCTTTGTGAAGGTGGCCCTCCAGGACTAG |
| Protein Properties | |
| Number of Residues | 756 |
| Molecular Weight | 86073.0 |
| Theoretical pI | 6.72 |
| Pfam Domain Function | Not Available |
| Signals |
|
| Transmembrane Regions | Not Available |
| Protein Sequence |
>1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-1 MDSGRDFLTLHGLQDDKDLQALLKGGQLLKVKSNSWRRERFYKLQEDCKTIWQESRKVMR TPESQLFSIEDIQEVRMGHRTEGLEKFARDVPENRCFSIVFKDQRNTLDLIAPSPADAQH WVQGLGKIIHHSGSMDQQQKLRHWIHSCLRKADKNKDNKMSFKELQNFLKELNIQVDDSY ARKIFKECDHSQTDSLEDEEIETFYKILTQRKEIDRTFEEATGSKETLSVDQLVTFLQHQ QREEEAGPALALSLIERYEPSETAKAQRQMTKDGFLMYLLSADGSAFDLAHRRVYQDMDQ PLSHYLVSSSHNTYLLEDQLTGPSSTEAYIRALCKGCRCLELDCWDGPNQEPIIYHGYTF TSKILFCDVVRAIRDYAFKASPYPVILSLENHCSLEQQRVMARHLRTLLGPMLLDRPLDG VVTSLPSPEQLRGKILLKGKKLGGLFPPGGEGGPEATVVSDEDEAAEMEDEAVRSQVQHK SKEDKLRLAKELSDMVIYCKSVHFRGFPSSGTSGQAFYEMSSFSENRALRLLQESGNSFV RHNVNHLSRIYPAGWRTDSSNYSPVEMWNGGCQIVALNFQTPGSEMDVYQGRFLDNGACG YVLKPAFLRDPNSTFNSRALAHGPWWTPKRLNVRVISGQQLPKVNKNKNSIVDPKVTVEI HGVSRDVASRQTAVVTNNGFNPWWDTELEFEVAVPELALVRFVVEDYDASSKNDFIGQST IPLKSLKQGYRHIHLLSKNGDQHPSATLFVKVALQD |
| External Links | |
| GenBank ID Protein | AAI33305.1 |
| UniProtKB/Swiss-Prot ID | P10895 |
| UniProtKB/Swiss-Prot Entry Name | PLCD1_BOVIN |
| PDB IDs | Not Available |
| GenBank Gene ID | BC133304 |
| GeneCard ID | PLCD1 |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| References | |
| General References | Not Available |