Identification |
BMDB Protein ID
| BMDBP00077 |
Secondary Accession Numbers
| None |
Name
| 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 |
Synonyms
|
Not Available
|
Gene Name
| PLCB4 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Replication, recombination and repair |
Specific Function
| The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. This form has a role in retina signal transduction. |
Pathways
|
Not Available
|
Reactions
| Not Available |
GO Classification
|
Not Available
|
Cellular Location
|
Not Available
|
Gene Properties |
Chromosome Location
| 13 |
Locus
| Not Available |
SNPs
| PLCB4 |
Gene Sequence
|
Not Available
|
Protein Properties |
Number of Residues
| 1023 |
Molecular Weight
| 117110.0 |
Theoretical pI
| 6.73 |
Pfam Domain Function
|
Not Available |
Signals
|
|
Transmembrane Regions
|
Not Available
|
Protein Sequence
|
>1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-4
PVRSITRTFASGKTEKVIFQALKELGLPSGKNDEIEPAAFTYEKFYELTQKICPRTDIED
LFKKINGDKTDYLTVDQLVSFLNEHQRDPRLNEILFPFYDAKRAMQIIEMYEPDEDLKKQ
GLISSDGFCRYLMSDENAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKSSVE
MYRQVLLAGCRCVELDCWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPV
ILSFENHCSKYQQYKMSKYCEDLFGDLLLKQALESHPLEPGRPLPSPNDLKRKILIKKQT
TETEVEKKQLEALKSMMEAGESAAPVNMLEDDNEEEIESAEQEEEAHPEYKYGNELSADD
LGHKEAIANSVKKASDDLEHENSKKGLVTVEDEQAWMASYKYVGATTNIHPYLSTMINYA
QPVKFQGFHVAEERNIHYNMSSFNESVGLGYLKTHAIEFVNYNKRQMSRIYPKGGRVDSS
NYMPQIFWNSGCQMVSLNYQTPDLAMQLNQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSE
TPVDGVIAATCSVQVISGQFLSDKKIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVY
NEESFVFRKVILPDLAVLRIAVYDDNNKLIGQRILPLDGLQAGYRHISLRNEGNKPLSLP
TIFCNIVLKTYVPDGFGDIVDALSDPKKFLSITEKRADQMRAMGIETSDIADVPSDTSKN
DKKGKANTAKANVTPQSSSELRPTTTAALGAGLEAKKGIELIPQVRIEDLKQMKAYLKHL
KKQQKELSSLKKKHAKEHSTMQKLHCTQVDKIVAQYDKEKLTHEKILEKAMKKKGGSNCL
EMKKETEIKIQTLTSDHKSKVKEIVAQHTKEWSDMINTHSAEEQEIRDLLLSQQCELLRK
LLISAHEQQTQQLKLSHDRESKEMRAHQAKISMENSKAISQDKSIKNKAERERRVRELNS
SNTKKFLEERKRLAMKQSKEMDQLKKVQLEHLEFVEKQNEQAKEMQQMVKLEAEMDRRPA
TVV
|
External Links |
GenBank ID Protein
| AAA30699.1 |
UniProtKB/Swiss-Prot ID
| Q07722 |
UniProtKB/Swiss-Prot Entry Name
| PLCB4_BOVIN |
PDB IDs
|
Not Available |
GenBank Gene ID
| L13936 |
GeneCard ID
| PLCB4 |
GenAtlas ID
| Not Available |
HGNC ID
| Not Available |
References |
General References
| Not Available |