Showing Protein Galactosylceramide sulfotransferase (BMDBP00080)
| Identification | |||||
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| BMDB Protein ID | BMDBP00080 | ||||
| Secondary Accession Numbers | None | ||||
| Name | Galactosylceramide sulfotransferase | ||||
| Synonyms | Not Available | ||||
| Gene Name | GAL3ST1 | ||||
| Protein Type | Enzyme | ||||
| Biological Properties | |||||
| General Function | Involved in galactosylceramide sulfotransferase activity | ||||
| Specific Function | Catalyzes the sulfation of membrane glycolipids. Seems to prefer beta-glycosides at the non-reducing termini of sugar chains attached to a lipid moiety. Catalyzes the synthesis of HSO3-3-galactosylceramide (sulfatide), a major lipid component of the myelin sheath and of HSO3-3-monogalactosylalkylacylglycerol (seminolipid), present in spermatocytes. Also acts on lactosylceramide, galactosyl 1-alkyl-2-sn-glycerol and galactosyl diacylglycerol (in vitro) (By similarity). | ||||
| Pathways |
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| Reactions |
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| GO Classification | Not Available | ||||
| Cellular Location | Not Available | ||||
| Gene Properties | |||||
| Chromosome Location | 17 | ||||
| Locus | Not Available | ||||
| SNPs | GAL3ST1 | ||||
| Gene Sequence |
>1272 bp ATGCCGCTGCCACAGAAGAAGCGCTGGGAGTCCATGGCCAAGGGGCTGGTGCTGGGAGCG CTCTTCACCAGCTTCCTGCTACTGCTGTACTCCTATGCTGTCCCCCCACTGTACACTGGC CTGGCTTCCACGACCCCCGAGGGCGCGGCACCCTGCTCTCCGGCCCCGAGGGAGCCAGAG GCTCCCACCTCGGCCAACGGCTCGGCGGGAGGCTGCCAGCCGCGGCGGGACATCGTGTTC ATGAAGACGCACAAGACGGCCAGCAGCACGCTGCTCAACATCCTGTTCCGCTTCGGCCAG AAGCACGGGCTCAAGTTCGCCTTCCCCAACGGCCGCAACGACTTCGACTACCCCGCCTTC TTCGCGCGCAGCCTGGTGCAGGACTACCGGCCCGGGGCCTGCTTCAACATCATCTGCAAC CACATGCGCTTCCACTACGACGAGGTGCGGGGCCTGGTGGCGCCCAACGCCACCTTCATC ACCGTGCTGCGCGACCCCGCCCGCCTCTTCGAGTCCTCCTTCCACTACTTCGGCTCCGTG GTGCCCTTCACGTGGAAGCTCTCGGGCCGCGACAAGCTGGCCGAGTTCCTGCAGGACCCC GACCGCTACTACGACGCCCGCGGCTACAACGCCCACTACCTCCGCAACCTGCTCTTCTTC GACCTGGGCTACGACAGCGACCTGGACCCCAGCAGCCCGCAGGTGCAGGAGCACATCCTG GAGGTGGAGCGCCACTTCCACCTGGTGCTGCTGCAGGAGTACTTCGACGAGTCGCTCGTG CTGCTCAAGGACCTGCTGTGCTGGGAGCTGGAGGACGTGCTCTACTTCAAGCTCAACGCC CGCCGCGCCTCGGCCGTGCCGCGCCTCTCGGGCGAGCTGTACCGGCGCGCCACGGCCTGG AACGTGCTGGACGCGCGCCTCTACCGCCACTTCAACGCCAGCTTCTGGCGCAAGGTGGAG GCCTTCGGGCGCGAGCGCATGGCCCGCGAGGTGGCCGCCCTGCGGCGCGCCAACGAGCGC ATGCGCCGCATCTGCATCGACGGCGGCCGCGCGGTGGACGCGGCGGCCATCGAGGACTCG GCCATGCAGCCCTGGCAGCCGCTGGGCGCCAAGTCCATCCTGGGCTACAACCTCAAGAAG AGCATCGGGCAGCGGCATGCGCAGCTCTGCCGGCGCATGCTCACGCCGGAGATCCAGTAC CTGATGGACCTGGGCGCCAACCTGTGGATCACCAAGCTCTGGAAGTTCATCCGGGACTTC CTGCGGTGGTGA |
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| Protein Properties | |||||
| Number of Residues | 423 | ||||
| Molecular Weight | 48754.0 | ||||
| Theoretical pI | 9.53 | ||||
| Pfam Domain Function | Not Available | ||||
| Signals |
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| Transmembrane Regions |
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| Protein Sequence |
>Galactosylceramide sulfotransferase MPLPQKKRWESMAKGLVLGALFTSFLLLLYSYAVPPLYTGLASTTPEGAAPCSPAPREPE APTSANGSAGGCQPRRDIVFMKTHKTASSTLLNILFRFGQKHGLKFAFPNGRNDFDYPAF FARSLVQDYRPGACFNIICNHMRFHYDEVRGLVAPNATFITVLRDPARLFESSFHYFGSV VPFTWKLSGRDKLAEFLQDPDRYYDARGYNAHYLRNLLFFDLGYDSDLDPSSPQVQEHIL EVERHFHLVLLQEYFDESLVLLKDLLCWELEDVLYFKLNARRASAVPRLSGELYRRATAW NVLDARLYRHFNASFWRKVEAFGRERMAREVAALRRANERMRRICIDGGRAVDAAAIEDS AMQPWQPLGAKSILGYNLKKSIGQRHAQLCRRMLTPEIQYLMDLGANLWITKLWKFIRDF LRW |
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| External Links | |||||
| GenBank ID Protein | AAI48871.1 | ||||
| UniProtKB/Swiss-Prot ID | A6QNK1 | ||||
| UniProtKB/Swiss-Prot Entry Name | G3ST1_BOVIN | ||||
| PDB IDs | Not Available | ||||
| GenBank Gene ID | BC148870 | ||||
| GeneCard ID | GAL3ST1 | ||||
| GenAtlas ID | Not Available | ||||
| HGNC ID | Not Available | ||||
| References | |||||
| General References | Not Available | ||||