| Identification |
|---|
| BMDB Protein ID
| BMDBP00095 |
| Secondary Accession Numbers
| |
| Name
| Membrane primary amine oxidase |
| Synonyms
|
Not Available
|
| Gene Name
| AOC3 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Secondary metabolites biosynthesis, transport and catabolism |
| Specific Function
| Cell adhesion protein that participates in lymphocyte recirculation by mediating the binding of lymphocytes to peripheral lymph node vascular endothelial cells in an L-selectin-independent fashion. Has a monoamine oxidase activity (By similarity). |
| Pathways
|
Not Available
|
| Reactions
|
| 1,3-Diaminopropane + Oxygen + Water → 3-Aminopropionaldehyde + Ammonia + Hydrogen peroxide |
details
|
| Histamine + Water + Oxygen → Imidazole-4-acetaldehyde + Ammonia + Hydrogen peroxide |
details
|
| Tyramine + Water + Oxygen → Homovanillin + Hydrogen peroxide + Ammonia |
details
|
|
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 19 |
| Locus
| Not Available |
| SNPs
| AOC3 |
| Gene Sequence
|
>2292 bp
ATGAACCAGAAGACCACCCTGGTGCTCCTTGCTCTGGCTGTCATCACCATCTTTGCCTTG
GTGTGTGTCTTAATAGCTGGCAGGGGAGGAGATGGGGGTGAAGCCAGCCAACCTCACTAC
TGCCCCTCCGGAACCCCCAGTGTCCAGCCCTGGACACACCCTGGCCAGAACCAGCTGTTT
GCAGACCTGAGCCGAGAAGAGCTGACAGCTGTGATGAGCTTCCTGACCCAGAAGCTGGGG
CCAGACCTGGTGGATGCAGCCCAGGCCCGACCCTCTGACAACTGCATCTTCTCGGTAGAG
CTGCAGCTGCCCCCCAAGGCTGCAGCCCTGGCCCACCTGGACAGGAGGAGCCCCCCACCT
GCCCGGGAGGCACTGGCCATCGTCTTCTTTGGTGGACAACCCCAGCCCAATGTGACTGAG
CTGGTGGTGGGGCCGCTGCCCCAGCCCTCCTACATGCGGGATGTGACCGTGGAGCGTCAT
GGGGGCCCCCTGCCCTATTACCGACGCCCCGTGCTTCTCCGAGAGTACCTGGACATAGAC
CAGATGATCTTCAACAGAGAGCTGCCCCAGGCTGCTGGTGTCCTGCACCACTGCTGCTCC
TACAAACAAGGAGGAGGGAACCTGGTGACCATGACCACAGCCCCCCGCGGTTTGCAATCA
GGTGACCGGGCCACCTGGTTTGGCCTCTACTACAACATCTCAGGGGCTGGGTACTATCTG
CACCCTGTGGGGTTAGAGCTGCTGGTAGATCACAAGGCTCTGGACCCTGCCCAGTGGACC
ATCCAGAAGGTGTTCTTTCAAGGCCGCTACTATGAAAGTCTGGCCCAGCTGGAGGAGCAG
TTTGAGGCTGGCCGGGTGAATGTGGTGGTGATCCCAAACAATGGCACAGGTGGGTCCTGG
TCCCTGAAGTCCCAGGTGCCCCCGGGTCCAACTCCACCTCTGCAGTTCCATCCTCAGGGC
ACCCGCTTCAGTGTCCAGGGCAGTCGAGTGACCTCCTCATTGTGGACTTTCTCCTTTGGC
CTCGGAGCTTTCAGTGGTCCTAGGATCTTTGACATTCGATTCCAAGGAGAACGACTGGCT
TATGAGATCAGCCTGCAAGAGGCCGTGGCTATTTATGGTGGGAATACCCCAGCAGCAATG
CTCACTCGCTATATGGATGGCTGCTTTGGCATGGGCAAGTTCGCCACGCCCCTGACCCGA
GGGGTGGACTGCCCCTATCTGGCCACCTATGTGGACTGGCACTTCCTTCTGGAGTCTCAA
GCCCCCAGGACCCTACATGATGCCTTTTGTGTGTTTGAGCAGAACAAGGGCCTGCCCCTG
AGGCGACACCACTCAGATTTTATTTCCCAGTATTTTGGGGGCGTTGTGGAGACAGTGCTG
GTCTTCAGATCTGTGTCAACCTTGCTCAACTATGACTATGTGTGGGATATGGTCTTTCAC
CCCAATGGGGCCATAGAAGTCAAATTCCATGCCACGGGCTATATCAGCTCAGCGTTCTTC
TTTGGTACTGCCCAAAAATACGGAAACCAGGTTCGGGAGAATACACTGGGCACCGTCCAC
ACCCACAGTGCCCACTACAAGGTGGATCTGGATGTGGGAGGACTGGAGAACTGGGTCTGG
GCTGAGGACATGGCTTTTGTCCCCACAACGGTACCCTGGAGCCCTGAGCACCAGATACAG
AGGCTGCAGGTGACCCGGAAGCAGCTGGAGACTGAGGAGCAGGCCGCCTTCCCCCTGGGA
GGGGCCTCCCCTCGCTACCTGTACCTGGCCAGCAAGCAGAGCAACAAGTGGGGGCACCCT
CGCGGCTATCGCATCCAGACGGTCAGCTTTGCTGGGAGGCCGCTGCCCCAGAACAGCTCC
ACAGAGAGAGCCATCAGCTGGGGGAGGTACCAGCTGGCCGTGACCCAGAGGAAGGAGACA
GAGCCCAGCAGCTCCAGCGTCTTCAATCAGAATGACCCCTGGACTCCCACTGTGGACTTT
GCTGACTTCATCAACAATGAGACCATTGCTGGAAAGGACTTGGTGGCCTGGGTGACAGCC
GGTTTCCTGCACATCCCTCATGCAGAGGACATTCCCAACACAGTGACAGTGGGGAACGGT
GTGGGCTTCTTTCTGCGACCCTACAACTTCTTTGATGAGGACCCCTCCATCAATTCTGCT
GACTCAATCTACTTCCAAAAACACCAGGATGCTGGGTCCTGTGAGGTCAACTCCCTGGCT
TGTCTGCCCAAGGATCCTGCCTGTGCCCCTGATCTCCCTGCCTTCTCCCACGGGGGCTTC
TTCACCAATTAG
|
| Protein Properties |
|---|
| Number of Residues
| 763 |
| Molecular Weight
| 84500.0 |
| Theoretical pI
| 6.51 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Membrane primary amine oxidase
MNQKTTLVLLALAVITIFALVCVLIAGRGGDGGEASQPHYCPSGTPSVQPWTHPGQNQLF
ADLSREELTAVMSFLTQKLGPDLVDAAQARPSDNCIFSVELQLPPKAAALAHLDRRSPPP
AREALAIVFFGGQPQPNVTELVVGPLPQPSYMRDVTVERHGGPLPYYRRPVLLREYLDID
QMIFNRELPQAAGVLHHCCSYKQGGGNLVTMTTAPRGLQSGDRATWFGLYYNISGAGYYL
HPVGLELLVDHKALDPAQWTIQKVFFQGRYYESLAQLEEQFEAGRVNVVVIPNNGTGGSW
SLKSQVPPGPTPPLQFHPQGTRFSVQGSRVTSSLWTFSFGLGAFSGPRIFDIRFQGERLA
YEISLQEAVAIYGGNTPAAMLTRYMDGCFGMGKFATPLTRGVDCPYLATYVDWHFLLESQ
APRTLHDAFCVFEQNKGLPLRRHHSDFISQYFGGVVETVLVFRSVSTLLNYDYVWDMVFH
PNGAIEVKFHATGYISSAFFFGTAQKYGNQVRENTLGTVHTHSAHYKVDLDVGGLENWVW
AEDMAFVPTTVPWSPEHQIQRLQVTRKQLETEEQAAFPLGGASPRYLYLASKQSNKWGHP
RGYRIQTVSFAGRPLPQNSSTERAISWGRYQLAVTQRKETEPSSSSVFNQNDPWTPTVDF
ADFINNETIAGKDLVAWVTAGFLHIPHAEDIPNTVTVGNGVGFFLRPYNFFDEDPSINSA
DSIYFQKHQDAGSCEVNSLACLPKDPACAPDLPAFSHGGFFTN
|
| External Links |
|---|
| GenBank ID Protein
| BAA88896.1 |
| UniProtKB/Swiss-Prot ID
| Q9TTK6 |
| UniProtKB/Swiss-Prot Entry Name
| AOC3_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AB019242 |
| GeneCard ID
| AOC3 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
