Showing Protein N-acetylneuraminate lyase (BMDBP00109)
| Identification | |||
|---|---|---|---|
| BMDB Protein ID | BMDBP00109 | ||
| Secondary Accession Numbers | None | ||
| Name | N-acetylneuraminate lyase | ||
| Synonyms | Not Available | ||
| Gene Name | NPL | ||
| Protein Type | Enzyme | ||
| Biological Properties | |||
| General Function | Amino acid transport and metabolism | ||
| Specific Function | Catalyzes the cleavage of N-acetylneuraminic acid (sialic acid) to form pyruvate and N-acetylmannosamine via a Schiff base intermediate. It prevents sialic acids from being recycled and returning to the cell surface. Involved in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway (By similarity). | ||
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| Reactions |
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| GO Classification | Not Available | ||
| Cellular Location | Not Available | ||
| Gene Properties | |||
| Chromosome Location | 16 | ||
| Locus | Not Available | ||
| SNPs | NPL | ||
| Gene Sequence |
>963 bp ATGGCCTCCCCAAAGAAGAAGCTCCAAGGTCTTGTTGCTGCGACCATCACGCCGATGACT GAGCATGGAGAAATCAACTTTTCAGTCATTGGTCGGTATGTGGACTATCTTGTAGAGGAA CAGGGAGTGAAGAATGTCTTTGTGAACGGCACGACGGGAGAAGGCCTGTCCCTGAGCATC TCGGAGCGCTGCCAGGTCGCAGAGGAGTGGGTGACAAAGGGGAAGAACAAGTTGGATCAG ATAGTAATTCATGTGGGAGCCTTGAGCTTGAAGGAGTCACAAGAACTGGCCCAACATGCA GCAGAAATAGGAGCCGACGGCATCGCTGTCATCGCACCTTTCTTTCTCAAGCCATGGAAC AAAGATGTCCTAATTAATTTCCTAAAAGAAGTGGCTGCTGCTGCCCCTGCATTGCCGTTT TACTACTATCACATCCCTGCCTTGACCGGGGTGAAGATTCGTGCTGAGGAACTGTTGGAT GGGATTCAGGATAAGATCCCCAGCTTCCAAGGGCTGAAATTCAGTGACACGGATCTCTTA GACTTCGGGCAGTGTGTGGATCAGAATCGCCAGCGACAGTTTGCTTTCCTTTTTGGGGTG GATGAGCAACTGTTAAGTGCTCTGGTGATGGGAGCAACTGGAGCGGTGGGCAGTACCTAT AACTACCTGGGAAAAAAGACAAAGCAGATGTTGGAGGCTTTTGAACGAAAGGACTTCTCT TCAGCTCTGAACCATCAGTTTTGTATTCAGAGATTTATCAACTTTGTGGTCAAACTAGGT TTTGGAGTGTCGCAGACCAAAGCCATCATGACCCTTGTCTCCGGGATTCCAATGGGCCCA CCCCGTCTTCCGCTACAGAAAGCCTCCAGGGAGTTTACTGATAATGCAGAAGCTAAACTG AAAAGCCTAGATTTCCTTTCTTGCACTGATTTAAAGGATGGAAATATGGAAGCTTGTAGC TAG |
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| Protein Properties | |||
| Number of Residues | 320 | ||
| Molecular Weight | 35166.0 | ||
| Theoretical pI | 6.37 | ||
| Pfam Domain Function | Not Available | ||
| Signals |
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| Transmembrane Regions | Not Available | ||
| Protein Sequence |
>N-acetylneuraminate lyase MASPKKKLQGLVAATITPMTEHGEINFSVIGRYVDYLVEEQGVKNVFVNGTTGEGLSLSI SERCQVAEEWVTKGKNKLDQIVIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWN KDVLINFLKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGIQDKIPSFQGLKFSDTDLL DFGQCVDQNRQRQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTKQMLEAFERKDFS SALNHQFCIQRFINFVVKLGFGVSQTKAIMTLVSGIPMGPPRLPLQKASREFTDNAEAKL KSLDFLSCTDLKDGNMEACS |
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| External Links | |||
| GenBank ID Protein | AAI13333.1 | ||
| UniProtKB/Swiss-Prot ID | Q29RY9 | ||
| UniProtKB/Swiss-Prot Entry Name | NPL_BOVIN | ||
| PDB IDs | Not Available | ||
| GenBank Gene ID | BC113332 | ||
| GeneCard ID | NPL | ||
| GenAtlas ID | Not Available | ||
| HGNC ID | Not Available | ||
| References | |||
| General References | Not Available | ||