Showing Protein Manganese-dependent ADP-ribose/CDP-alcohol diphosphatase (BMDBP00133)
| Identification | |
|---|---|
| BMDB Protein ID | BMDBP00133 |
| Secondary Accession Numbers | None |
| Name | Manganese-dependent ADP-ribose/CDP-alcohol diphosphatase |
| Synonyms | Not Available |
| Gene Name | ADPRM |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Involved in ADP-ribose diphosphatase activity |
| Specific Function | Hydrolyzes ADP-ribose, IDP-ribose, CDP-glycerol, CDP-choline and CDP-ethanolamine, but not other non-reducing ADP-sugars or CDP-glucose. May be involved in immune cell signaling as suggested by the second-messenger role of ADP-ribose, which activates TRPM2 as a mediator of oxidative/nitrosative stress (By similarity). |
| Pathways | Not Available |
| Reactions | Not Available |
| GO Classification | Not Available |
| Cellular Location | Not Available |
| Gene Properties | |
| Chromosome Location | 19 |
| Locus | Not Available |
| SNPs | ADPRM |
| Gene Sequence |
>618 bp ATGGATTATAAGCCCGAACCTGAACTCCACAGTGAGAGCTCTGAACGTCTCTTCTCCTTT GGAGTGATAGCAGATATTCAATATGCTGATTTGGAAGATGGCTATAATTTCCAGGGAAAC AGAAGGAGGTACTACAGACACAGTCTTCTTCACTTACAGGGTGCTATCGAACACTGGAAT CAAGAACGCAGCCCGCCCCGTTGTGTGCTTCAGCTTGGAGACATCATCGACGGATACAAT GCGCAGTACAAAGCATCAGAAAAGTCACTGGAGCGCGTCATGAACACATTCCAAATGCTG AGAGTCCCTGTTCATCACACGTGGGGAAACCACGAATTCTATAATTTCAGCAGAGACTAT TTAACAAACTCCAAACTTAACACAAAGTTTCTGGAAGACCAGATTGCCCACCATCCTGAG ACTGTGCCCTCGGAGGATTATTACGCGTATCATTTTGTACCATTCCCTAAATTCCGCTTC ATTTTACTCGATGCTTATGACATGAGTGTCTTGGGCGTGGATCAGTCTTCTCCAAAATAC CAGCAGTGTCTGAAGATACTGAGGGAGCACAACCCAAATACGGAACTGAATAGTCCTCAA GGTGAATTATTCCTTTGA |
| Protein Properties | |
| Number of Residues | 337 |
| Molecular Weight | 39235.0 |
| Theoretical pI | 6.29 |
| Pfam Domain Function | Not Available |
| Signals |
|
| Transmembrane Regions | Not Available |
| Protein Sequence |
>Manganese-dependent ADP-ribose/CDP-alcohol diphosphatase MDYKPEPELHSESSERLFSFGVIADIQYADLEDGYNFQGNRRRYYRHSLLHLQGAIEHWN QERSPPRCVLQLGDIIDGYNAQYKASEKSLERVMNTFQMLRVPVHHTWGNHEFYNFSRDY LTNSKLNTKFLEDQIAHHPETVPSEDYYAYHFVPFPKFRFILLDAYDMSVLGVDQSSPKY QQCLKILREHNPNTELNSPQGLREPQFVQFNGGFSPEQLNWLNAVLTFSDRNQEKVVIVS HLPIYPEASDSVCLAWNYRDALAVIWSHKCVVCFFAGHTHDGGYSEDPYGVHHVNIEGVI ETAPDSQAFGTVHVYPDKMMLEGRGRVPHRIMNYRKE |
| External Links | |
| GenBank ID Protein | AAI51326.1 |
| UniProtKB/Swiss-Prot ID | A7YY53 |
| UniProtKB/Swiss-Prot Entry Name | ADPRM_BOVIN |
| PDB IDs | Not Available |
| GenBank Gene ID | AAFC03054081 |
| GeneCard ID | ADPRM |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| References | |
| General References | Not Available |