Showing Protein CTD nuclear envelope phosphatase 1 (BMDBP00139)
| Identification | |
|---|---|
| BMDB Protein ID | BMDBP00139 |
| Secondary Accession Numbers | None |
| Name | CTD nuclear envelope phosphatase 1 |
| Synonyms | Not Available |
| Gene Name | CTDNEP1 |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Involved in protein serine/threonine phosphatase activity |
| Specific Function | Serine/threonine protein phosphatase forming with CNEP1R1 an active phosphatase complex that dephosphorylates and may activate LPIN1 and LPIN2. LPIN1 and LPIN2 are phosphatidate phosphatases that catalyze the conversion of phosphatidic acid to diacylglycerol and control the metabolism of fatty acids at different levels. May indirectly modulate the lipid composition of nuclear and/or endoplasmic reticulum membranes and be required for proper nuclear membrane morphology and/or dynamics. May also indirectly regulate the production of lipid droplets and triacylglycerol. May antagonize BMP signaling (By similarity). |
| Pathways | Not Available |
| Reactions | Not Available |
| GO Classification | Not Available |
| Cellular Location | Not Available |
| Gene Properties | |
| Chromosome Location | 19 |
| Locus | Not Available |
| SNPs | CTDNEP1 |
| Gene Sequence |
>735 bp ATGATGAGGACGCAGTGTCTGCTGGGGCTGCGCACGTTCGTGGCCTTCGCCGCCAAGCTC TGGAGCTTCTTCATTTACCTTTTGAGGAGGCAGATCCGCACGGTAATTCAGTACCAAACT GTTCGATATGACATCCTTCCCTTATCTCCTGTGTCCCGGAATCGGCTAAGCCAGGTGAAG AGGAAGATCCTGGTGCTGGATCTGGATGAGACACTTATTCACTCCCATCATGATGGGGTC CTGAGGCCCACAGTCCGGCCTGGAACGCCTCCTGACTTCATTCTCAAGGTGGTAATAGAC AAACATCCCGTCCGGTTTTTTGTACATAAGAGGCCCCATGTGGATTTCTTCTTGGAAGTG GTGAGCCAGTGGTACGAGTTGGTGGTGTTCACAGCAAGCATGGAGATTTATGGCTCTGCT GTGGCAGATAAACTGGATAATAGCAGAAGCATTCTCAAGAGAAGATACTACAGACAACAC TGCACTTTGGAATTGGGCAGCTACATCAAGGACCTCTCTGTGGTCCACAGTGACCTCTCC AGCATTGTGATCCTGGATAACTCCCCAGGGGCTTACAGGAGCCATCCAGACAATGCCATC CCCATCAAATCCTGGTTCAGTGATCCCAGTGATACCGCCCTTCTCAACCTGCTTCCAATG CTGGATGCCCTCAGGTTCACCGCTGATGTTCGTTCTGTGCTGAGCCGAAACCTTCACCAA CATAGGCTCTGGTGA |
| Protein Properties | |
| Number of Residues | 244 |
| Molecular Weight | 28393.0 |
| Theoretical pI | 10.19 |
| Pfam Domain Function | Not Available |
| Signals |
|
| Transmembrane Regions |
|
| Protein Sequence |
>Serine/threonine-protein phosphatase dullard MMRTQCLLGLRTFVAFAAKLWSFFIYLLRRQIRTVIQYQTVRYDILPLSPVSRNRLSQVK RKILVLDLDETLIHSHHDGVLRPTVRPGTPPDFILKVVIDKHPVRFFVHKRPHVDFFLEV VSQWYELVVFTASMEIYGSAVADKLDNSRSILKRRYYRQHCTLELGSYIKDLSVVHSDLS SIVILDNSPGAYRSHPDNAIPIKSWFSDPSDTALLNLLPMLDALRFTADVRSVLSRNLHQ HRLW |
| External Links | |
| GenBank ID Protein | AAI14678.1 |
| UniProtKB/Swiss-Prot ID | Q1RMV9 |
| UniProtKB/Swiss-Prot Entry Name | CNEP1_BOVIN |
| PDB IDs | Not Available |
| GenBank Gene ID | BC114677 |
| GeneCard ID | CTDNEP1 |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| References | |
| General References | Not Available |