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| Identification |
|---|
| BMDB Protein ID
| BMDBP00140 |
| Secondary Accession Numbers
| None |
| Name
| 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 |
| Synonyms
|
Not Available
|
| Gene Name
| PFKFB1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Carbohydrate transport and metabolism |
| Specific Function
| Synthesis and degradation of fructose 2,6-bisphosphate. |
| Pathways
|
- Fructose and Mannose Degradation
|
| Reactions
|
| D-Fructose 2,6-bisphosphate + Water → Fructose 6-phosphate + Hydrogen phosphate |
details
|
|
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| X |
| Locus
| Not Available |
| SNPs
| PFKFB1 |
| Gene Sequence
|
>1416 bp
ATGTCTCAAGAGATGGGAGAGCTCACCCAAACCAGATTGCAGAAGATCTGGATTCCACAC
AACAACGGCAACAGCAGGCTTCAACGGAGGAGGGGCTCATCCATACCACAGTTTACAAAT
TCCCCCACAATGGTGATCATGGTGGGTTTACCAGCTCGAGGAAAGACCTACATCTCAACA
AAGCTCACACGCTATCTCAACTGGATAGGAACACCAACTAAAGTGTTTAATTTAGGCCAA
TATCGACGAGAGGCAGTGAGCTACAAGAACTACGAATTCTTTCTTCCCGACAACATGGAG
GCCCTACTTATCAGGAAGCAGTGTGCCCTAGCAGCCCTGAAAGATGTTCATAGCTATCTC
AGCCATGAGGAAGGTCGTGTTGCAGTTTTTGATGCCACCAACACTACCAGAGAACGACGG
TCACTGATTCTGCAGTTTGCTAAAGAACATGGTTACAAGGTCTTTTTCATTGAGTCCATT
TGTAATGACCCTGACGTCATTGCAGAAAACATCAGGCAAGTGAAACTTGGCAGTCCTGAT
TATATAGACTGTGATCGTGAAAAGGTTCTGGAAGATTTTCTAAAGAGAATAGAGTGCTAT
GAGGTCAACTACCAACCCTTGGATGATGAACTGGATAGCCACCTGTCCTACATCAAGATC
TTCGACGTGGGCACACGCTACATGGTGAATCGTGTGCAGGACCATATCCAGAGCCGCACA
GTCTACTATCTCATGAACATTCACGTCACACCCCGCTCCATCTACCTATGCCGGCACGGT
GAGAGTGAACTCAACCTCAGAGGCCGCATTGGAGGTGACTCTGGCCTCTCAGCTCGGGGC
AAGCAGTATGCCTATGCCCTGGCCAATTTCATTCAGTCCCAGGGTATCAGCTCACTGAAG
GTTGGGACCAGCCACATGAAGAGGACTATCCAGACAGCTGAAGCCTTAGGACTTCCCTAT
GAGCAATGGAAGGCCCTGAATGAGATTGATGCGGGTGTCTGTGAGGAGATGACCTATGAA
GAAATCCAAGAACACTACCCTGAAGAATTTGCACTGCGAGACCAAGATAAATACCGCTAC
CGCTATCCTAAGGGAGAGTCTTACGAGGATCTGGTCCAGCGTCTGGAGCCAGTTATAATG
GAGCTAGAACGGCAGGAAAATGTATTGGTGATCTGCCATCAGGCTGTCATGCGGTGCCTC
CTGGCCTACTTTCTGGACAAGAGCTCAGATGAGTTGCCTTATCTCAAGTGCCCTCTCCAC
ACAGTGCTCAAACTTACACCTGTGGCTTATGGCTGCAAAGTGGAGTCCATCTACCTGAAT
GTGGAGGCTGTAAACACACATCGGGAGAAACCTGAGAATGTGGACATCACCCGGGAACCT
GAAGAAGCCCTGGACACTGTTCCTGCCCACTACTGA
|
| Protein Properties |
|---|
| Number of Residues
| 471 |
| Molecular Weight
| 54657.0 |
| Theoretical pI
| 6.51 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
MSQEMGELTQTRLQKIWIPHNNGNSRLQRRRGSSIPQFTNSPTMVIMVGLPARGKTYIST
KLTRYLNWIGTPTKVFNLGQYRREAVSYKNYEFFLPDNMEALLIRKQCALAALKDVHSYL
SHEEGRVAVFDATNTTRERRSLILQFAKEHGYKVFFIESICNDPDVIAENIRQVKLGSPD
YIDCDREKVLEDFLKRIECYEVNYQPLDDELDSHLSYIKIFDVGTRYMVNRVQDHIQSRT
VYYLMNIHVTPRSIYLCRHGESELNLRGRIGGDSGLSARGKQYAYALANFIQSQGISSLK
VGTSHMKRTIQTAEALGLPYEQWKALNEIDAGVCEEMTYEEIQEHYPEEFALRDQDKYRY
RYPKGESYEDLVQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKSSDELPYLKCPLH
TVLKLTPVAYGCKVESIYLNVEAVNTHREKPENVDITREPEEALDTVPAHY
|
| External Links |
|---|
| GenBank ID Protein
| AAA30696.1 |
| UniProtKB/Swiss-Prot ID
| P49872 |
| UniProtKB/Swiss-Prot Entry Name
| F261_BOVIN |
| PDB IDs
|
|
| GenBank Gene ID
| M64323 |
| GeneCard ID
| PFKFB1 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
