Showing Protein [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial (BMDBP00142)
| Identification | |
|---|---|
| BMDB Protein ID | BMDBP00142 |
| Secondary Accession Numbers | None |
| Name | [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial |
| Synonyms | Not Available |
| Gene Name | BCKDK |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Signal transduction mechanisms |
| Specific Function | Catalyzes the phosphorylation and inactivation of the branched-chain alpha-ketoacid dehydrogenase complex, the key regulatory enzyme of the valine, leucine and isoleucine catabolic pathways. Key enzyme that regulate the activity state of the BCKD complex. |
| Pathways |
|
| Reactions | Not Available |
| GO Classification | Not Available |
| Cellular Location | Not Available |
| Gene Properties | |
| Chromosome Location | 25 |
| Locus | Not Available |
| SNPs | BCKDK |
| Gene Sequence |
>1239 bp ATGATACTGGCTTCGGTGCTGGGGAGCGGACCCCGGGGCGGGCCACCCCTCCGGCCTCTC TTGGGGCCCGCACTCTCGCTCCGGGCCCGCTCCACATCAGCCACTGATACCCACCATGTG GAAATGGCACGGGAGCGCTCTAAGACCGTCACCTCCTTTTACAACCAGTCAGCCATTGAC GTCGCAGCGGAGAAGCCTTCAGTCCGCCTCACTCCAACCATGATGCTCTATTCAGGCCGC TCCCAGGATGGCAGTCACCTCCTGAAAAGTGCCCGCTACTTGCAGCAGGAGTTGCCAGTG AGGATCGCTCACCGCATCAAGGGCTTCCGCAGCCTTCCTTTCATCATTGGCTGCAACCCC ACCATACTGCACGTGCACGAGCTGTACATCCGTGCCTTCCAGAAGCTGACAGACTTCCCT CCGATCAAGGACCAGGCGGATGAGGCCCGATACTGCCAGCTGGTGCGACAGCTGTTGGAT GACCACAAGGACGTGGTGACCCTCTTAGCGGAAGGCCTGCGTGAGAGCCGGAAGTACATA GAGGATGAGAAGCTCGTCCGTTACTTCTTAGACAAGACGTTGACTTCAAGGCTTGGGATC CGTATGTTGGCCACCCACCATCTGGCACTACATGAGGACAAGCCCGACTTTGTTGGCATC ATCTGCACTCGCCTGTCACCGAAGAAGATTATTGAAAAGTGGGTGGACTTTGCCAGACGC CTGTGTGAGCACAAGTATGGCAATGCACCCCGAGTCCGCATCAACGGACACGTGGCTGCC CGTTTCCCCTTCATCCCAATGCCACTGGACTACATCCTACCTGAGCTGCTCAAGAACGCC ATGAGAGCCACAATGGAGAGTCACCTCGACACTCCCTACAATGTCCCAGATGTCGTCATC ACCATCGCCAACAATGATATCGATCTCGTCATCAGGATTTCAGACCGGGGCGGGGGAATT GCTCACAAAGACCTGGATCGGGTGATGGACTACCACTTCACTACAGCTGAGGCCAGCACC CAGGACCCCCGGATCAGCCCCCTCTTTGGCCACCTGGACTTGCACAGTGGTGGCCAGTCA GGACCCATGCACGGCTTTGGCTTCGGGCTGCCCACTTCGCGGGCCTACGCAGAGTACCTC GGTGGTTCCCTTCGGCTGCAGTCGCTGCAGGGCATTGGCACAGATGTCTACCTACGGCTC CGTCACATCGATGGCCGGGAAGAAAGCTTCCGCATCTGA |
| Protein Properties | |
| Number of Residues | 412 |
| Molecular Weight | 46438.0 |
| Theoretical pI | 9.48 |
| Pfam Domain Function | Not Available |
| Signals |
|
| Transmembrane Regions | Not Available |
| Protein Sequence |
>[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial MILASVLGSGPRGGPPLRPLLGPALSLRARSTSATDTHHVEMARERSKTVTSFYNQSAID VAAEKPSVRLTPTMMLYSGRSQDGSHLLKSARYLQQELPVRIAHRIKGFRSLPFIIGCNP TILHVHELYIRAFQKLTDFPPIKDQADEARYCQLVRQLLDDHKDVVTLLAEGLRESRKYI EDEKLVRYFLDKTLTSRLGIRMLATHHLALHEDKPDFVGIICTRLSPKKIIEKWVDFARR LCEHKYGNAPRVRINGHVAARFPFIPMPLDYILPELLKNAMRATMESHLDTPYNVPDVVI TIANNDIDLVIRISDRGGGIAHKDLDRVMDYHFTTAEASTQDPRISPLFGHLDLHSGGQS GPMHGFGFGLPTSRAYAEYLGGSLRLQSLQGIGTDVYLRLRHIDGREESFRI |
| External Links | |
| GenBank ID Protein | AAI05353.1 |
| UniProtKB/Swiss-Prot ID | Q2KJG8 |
| UniProtKB/Swiss-Prot Entry Name | BCKD_BOVIN |
| PDB IDs | |
| GenBank Gene ID | BC105352 |
| GeneCard ID | BCKDK |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| References | |
| General References | Not Available |