Showing Protein Beta-adrenergic receptor kinase 2 (BMDBP00166)
| Identification | |
|---|---|
| BMDB Protein ID | BMDBP00166 |
| Secondary Accession Numbers | None |
| Name | Beta-adrenergic receptor kinase 2 |
| Synonyms | Not Available |
| Gene Name | GRK3 |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Involved in ATP binding |
| Specific Function | Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. |
| Pathways | Not Available |
| Reactions | Not Available |
| GO Classification | Not Available |
| Cellular Location | Not Available |
| Gene Properties | |
| Chromosome Location | 17 |
| Locus | Not Available |
| SNPs | GRK3 |
| Gene Sequence |
>2067 bp ATGGCGGACCTGGAGGCCGTGCTGGCCGATGTCAGCTACCTGATGGCGATGGAGAAGAGC AAGGCGACCCCGGCCGCCCGCGCCAGCAAGAAGATCGTCCTGCCCGAGCCCAGTATCCGG AGCGTGATGCAGAAGTATCTTGAGGAGAGACACGAAATCACCTTTGACAAGATTTTTAAT CAGAGAATTGGTTTCTTGCTATTTAAAGATTTTTGTTTGAATGAAATTAATGAAGCTGTA CCTCAGGTGAAGTTTTATGAAGAGATAAAAGAATATGAAAAGCTTGAGAATGAGGAAGAT CGCCTTTGTAGAAGTCGACAGATTTATGACACTTACATCATGAAGGAGCTGCTGTCGTGT TCACATCCATTCTCAAAGCAAGCCGTAGAACACGTACAAAGTCATCTGTCCAAGAAACAA GTGACATCAACTCTTTTTCAGCCATACATAGAAGAAATTTGTGAAAGTCTCCGAGGCAGC ATTTTTCAAAAATTCATGGAAAGTGACAAGTTTACTAGATTTTGTCAGTGGAAAAACGTG GAATTAAATATCCATTTGACCATGAATGATTTCAGCGTGCATCGGATCATTGGACGAGGA GGATTCGGTGAAGTATACGGTTGCAGGAAAGCAGACACTGGAAAGATGTATGCAATGAAA TGCTTGGATAAGAAGAGAATCAAGATGAAACAGGGAGAAACCTTAGCCTTAAATGAAAGG ATCATGTTGTCCCTGGTGAGCACAGGAGATTGCCCTTTCATCGTCTGTATGACCTATGCC TTCCACACTCCAGATAAACTGTGCTTCATCTTGGATCTGATGAACGGGGGTGACCTGCAC TATCACCTTTCGCAGCACGGGGTGTTTTCTGAGAAGGAGATGCGGTTTTACGCCACAGAA ATCATCCTGGGGCTGGAACACATGCACAATCGGTTTGTTGTTTACAGAGACTTGAAGCCC GCCAATATCCTCCTGGATGAGCACGGACATGTGAGGATATCAGACCTTGGTCTTGCCTGC GATTTTTCCAAAAAGAAGCCGCACGCGAGCGTGGGCACCCACGGGTACATGGCGCCCGAA GTTCTGCAGAAGGGGACCGCCTACGACAGCAGTGCCGACTGGTTCTCCCTGGGCTGTATG CTTTTCAAACTTCTGAGAGGTCACAGCCCTTTCAGACAACATAAAACCAAAGATAAGCAT GAGATAGACCGAATGACTCTCACCATGAACGTGGAACTTCCAGACGTCTTCTCCCCTGAG CTCAAGTCCCTTCTGGAAGGCCTGCTTCAGCGAGATGTCAGTAAGCGCCTCGGCTGCCAT GGAGGCAGCGCACAGGAGCTAAAAACGCACGACTTCTTCAGAGGCATCGACTGGCAGCAC GTCTACCTGCAGAAGTACCCTCCACCCTTGATCCCTCCCCGAGGGGAAGTCAATGCAGCC GACGCCTTTGACATCGGCTCATTTGATGAAGAGGATACCAAAGGCATCAAGCTTCTTGAT TGCGACCAAGAACTCTACAAGAACTTCCCTCTGGTGATCTCTGAGCGCTGGCAGCAGGAA GTGGCGGAAACAGTTTATGAAGCAGTAAATGCAGACACGGATAAAATCGAGGCCAGGAAG AGAGCTAAAAATAAGCAGCTTGGCCACGAAGAAGATTACGCCCTGGGAAGAGACTGCATC GTGCACGGGTACATGCTGAAGCTGGGGAACCCTTTCCTGACCCAGTGGCAGCGCCGCTAT TTTTACCTCTTTCCGAACAGACTTGAGTGGAGAGGAGAAGGCGAGTCGCGACAAAGTTTA CTGACAATGGAACAGATTGTGTCCGTGGAAGAAACTCAGATTAAAGACAAAAAGTGCATT TTGTTGAGAATAAAAGGAGGGAAGCAGTTCGTTTTGCAGTGTGAGAGTGACCCAGAGTTT GTGCAGTGGAAGAAAGAGCTGACGGAGACATTCATGGAGGCCCAGCGGCTGCTACGGCGA GCCCCCAAGTTCCTCAACAAATCCCGCTCAGCCGTCGTGGAACTCTCAAAGCCTCCCCTC TGCCATAGGAACAGCAACGGCCTCTGA |
| Protein Properties | |
| Number of Residues | 688 |
| Molecular Weight | 79804.0 |
| Theoretical pI | 7.56 |
| Pfam Domain Function | Not Available |
| Signals |
|
| Transmembrane Regions | Not Available |
| Protein Sequence |
>Beta-adrenergic receptor kinase 2 MADLEAVLADVSYLMAMEKSKATPAARASKKIVLPEPSIRSVMQKYLEERHEITFDKIFN QRIGFLLFKDFCLNEINEAVPQVKFYEEIKEYEKLENEEDRLCRSRQIYDTYIMKELLSC SHPFSKQAVEHVQSHLSKKQVTSTLFQPYIEEICESLRGSIFQKFMESDKFTRFCQWKNV ELNIHLTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNER IMLSLVSTGDCPFIVCMTYAFHTPDKLCFILDLMNGGDLHYHLSQHGVFSEKEMRFYATE IILGLEHMHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKKPHASVGTHGYMAPE VLQKGTAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTMNVELPDVFSPE LKSLLEGLLQRDVSKRLGCHGGSAQELKTHDFFRGIDWQHVYLQKYPPPLIPPRGEVNAA DAFDIGSFDEEDTKGIKLLDCDQELYKNFPLVISERWQQEVAETVYEAVNADTDKIEARK RAKNKQLGHEEDYALGRDCIVHGYMLKLGNPFLTQWQRRYFYLFPNRLEWRGEGESRQSL LTMEQIVSVEETQIKDKKCILLRIKGGKQFVLQCESDPEFVQWKKELTETFMEAQRLLRR APKFLNKSRSAVVELSKPPLCHRNSNGL |
| External Links | |
| GenBank ID Protein | AAA30406.1 |
| UniProtKB/Swiss-Prot ID | P26818 |
| UniProtKB/Swiss-Prot Entry Name | ARBK2_BOVIN |
| PDB IDs | Not Available |
| GenBank Gene ID | M73216 |
| GeneCard ID | GRK3 |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| References | |
| General References | Not Available |