Showing Protein Dynamin-2 (BMDBP00170)
| Identification | |
|---|---|
| BMDB Protein ID | BMDBP00170 |
| Secondary Accession Numbers | None |
| Name | Dynamin-2 |
| Synonyms | Not Available |
| Gene Name | DNM2 |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Involved in GTP binding |
| Specific Function | Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Plays a role in the regulation of neuron morphology, axon growth and formation of neuronal growth cones (By similarity). Plays an important role in vesicular trafficking processes, in particular endocytosis. Involved in cytokinesis. Regulates maturation of apoptotic cell corpse-containing phagosomes by recruiting PIK3C3 to the phagosome membrane. |
| Pathways | Not Available |
| Reactions | Not Available |
| GO Classification | Not Available |
| Cellular Location | Not Available |
| Gene Properties | |
| Chromosome Location | 7 |
| Locus | Not Available |
| SNPs | DNM2 |
| Gene Sequence |
>2601 bp ATGGGCAACCGCGGGATGGAAGAGCTGATCCCGCTGGTCAACAAGCTGCAGGATGCCTTC AGTTCCATCGGCCAGAGCTGCCACCTGGACCTGCCGCAGATCGCCGTGGTGGGCGGCCAG AGCGCCGGCAAGAGCTCTGTGCTCGAGAACTTCGTGGGCCGGGACTTCCTTCCCCGAGGT TCAGGAATCGTCACTCGGCGGCCTCTCATCCTGCAGCTCATCTTCTCAAAAACAGAATAT GCCGAGTTTTTGCACTGCAAGTCCAGAAAGTTTACAGACTTTGAGGAAGTCCGACAGGAG ATCGAAGCGGAGACTGACAGGGTCACGGGGACCAACAAGGGCATCTCCCCAGTGCCCATT AACCTGCGGATCTACTCGCCACACGTGTTGAACCTGACCCTCATCGACCTCCCAGGCATC ACAAAGGTGCCTGTGGGGGACCAGCCCCAGGATATCGAGTACCAGATCAAGGACATGATC TTGCAGTTCATCAGCCGGGAAAGCAGCCTCATCCTTGCTGTCACCCCCGCCAACATGGAC CTGGCCAACTCAGACGCCCTAAAGCTGGCCAAGGAGGTCGATCCTCAAGGCCTGCGGACC ATCGGCGTCATCACCAAACTCGACCTGATGGACGAAGGCACGGATGCCAGGGATGTCCTG GAGAACAAGCTACTCCCCTTGAGGAGAGGCTACATTGGAGTGGTCAACCGCAGCCAGAAG GATATTGAGGGCAAGAAGGACATCCGCACAGCACTGGCGGCCGAGAGGAAGTTTTTCCTC TCCCACCCAGCCTACCGGCACATAGCTGACCGCATGGGCACCCCGCACCTGCAGAAGACT CTGAATCAGCAACTGACCAACCACATCCGGGAATCACTGCCGGCCCTGCGCAGCAAGCTG CAGAGCCAGCTGCTATCCCTGGAGAAGGAGGTGGAGGAGTACAAGAACTTCCGGCCCGAT GACCCCACACGCAAGACCAAAGCTCTCCTGCAGATGGTCCAGCAGTTTGGGGTGGACTTT GAGAAGAGGATTGAGGGCTCTGGAGACCAGGTGGACACACTGGAGCTCTCTGGGGGCGCC CGGATCAATCGCATCTTCCACGAGCGATTTCCCTTCGAGCTGGTGAAGATGGAGTTTGAT GAGAAAGACTTAAGACGGGAGATCAGCTACGCCATTAAAAATATCCACGGAGTCAGGACC GGGCTCTTCACCCCGGACTTGGCATTCGAGGCCATTGTGAAAAAGCAGGTCGTCAAGCTG AAAGAGCCCTGTCTGAAATGTGTCGACCTGGTTATCCAGGAGCTAATCAATACAGTTAGG CAGTGTACCAGTAAGCTCAGCTCCTACCCGCGGTTGCGAGAGGAAACGGAACGCATCGTC ACCACTTACATCCGGGAACGGGAGGGGAGGACCAAGGACCAGATTCTTCTTCTGATTGAC ATTGAGCAGTCCTACATCAACACCAACCACGAGGACTTCATTGGATTTGCCAACGCCCAG CAGAGGAGCACACAGCTGAATAAGAAGAGAGCCGTCCCCAACCAGGTGATCCGCAGGGGC TGGCTAACCATCAACAATATCAGCCTGATGAAGGGAGGCTCCAAGGAGTACTGGTTCGTG CTGACGGCCGAGTCACTGTCCTGGTACAAGGATGAGGAGGAGAAAGAGAAGAAGTACATG CTGCCTCTGGACAACCTCAAAATCCGTGACGTGGAGAAGGGCTTCATGTCCAACAAGCAC GTCTTCGCCATCTTCAACACAGAGCAGAGGAATGTCTACAAGGACCTGCGGCAGATCGAG CTGGCCTGTGACTCCCAGGAGGACGTGGACAGCTGGAAGGCCTCATTCCTCCGAGCTGGG GTCTATCCAGAGAAGGACCAGGCAGAAAATGAGGATGGAGCCCAGGAGAACACCTTCTCC ATGGACCCGCAGTTGGAGCGGCAGGTGGAGACCATTCGCAACCTGGTGGACTCGTACGTG GCCATAATCAACAAGTCCATCCGTGACCTCATGCCAAAGACCATCATGCACCTCATGATC AACAACACGAAGGCCTTCATCCACTATGAGCTGCTGGCCTACCTGTACTCGTCGGCGGAC CAGAGCAGCCTCATGGAAGAGTCGGCTGACCAGGCCCAGCGGCGGGATGACATGCTTCGC ATGTACCACGCGCTCAAGGAGGCACTCAACATCATTGGGGACATCAGCACCAGCACTGTG TCCACTCCCGTGCCCCCACCCGTTGACGACACCTGGATCCAGAACACCAGCAGCCACAGC CCCACTCCGCAGCGCCGGCCCGTATCCAGCGTGCACCCCCCAGGCCGGCCCCCAGCAGTG AGGGGTCCCACCCCAGGGCCACCCCTGATTCCTGTGCCGGTGGGGCCAGCTTCCTTCTCA GCGCCCCCGATCCCATCCCGGCCCGGCCCCCACCCCGGCGTGTTTGCCAACAACGACCCC TTCTCGGCCCCACCTCAGATCCCATCTCGGCCGGCTCGGATTCCACCCGGCATTCCCCCT GGAGTGCCCAGCAGAAGACCCCCTGCTGCGCCCAGCCGGCCCACCATTATCCGCCCAGCC GAGCCATCTCTGCTCGACTAG |
| Protein Properties | |
| Number of Residues | 866 |
| Molecular Weight | 97836.0 |
| Theoretical pI | 7.69 |
| Pfam Domain Function | Not Available |
| Signals |
|
| Transmembrane Regions |
|
| Protein Sequence |
>Dynamin-2 MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG SGIVTRRPLILQLIFSKTEYAEFLHCKSRKFTDFEEVRQEIEAETDRVTGTNKGISPVPI NLRIYSPHVLNLTLIDLPGITKVPVGDQPQDIEYQIKDMILQFISRESSLILAVTPANMD LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK DIEGKKDIRTALAAERKFFLSHPAYRHIADRMGTPHLQKTLNQQLTNHIRESLPALRSKL QSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGA RINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDLAFEAIVKKQVVKL KEPCLKCVDLVIQELINTVRQCTSKLSSYPRLREETERIVTTYIREREGRTKDQILLLID IEQSYINTNHEDFIGFANAQQRSTQLNKKRAVPNQVIRRGWLTINNISLMKGGSKEYWFV LTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDLRQIE LACDSQEDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLVDSYV AIINKSIRDLMPKTIMHLMINNTKAFIHYELLAYLYSSADQSSLMEESADQAQRRDDMLR MYHALKEALNIIGDISTSTVSTPVPPPVDDTWIQNTSSHSPTPQRRPVSSVHPPGRPPAV RGPTPGPPLIPVPVGPASFSAPPIPSRPGPHPGVFANNDPFSAPPQIPSRPARIPPGIPP GVPSRRPPAAPSRPTIIRPAEPSLLD |
| External Links | |
| GenBank ID Protein | AAI46260.1 |
| UniProtKB/Swiss-Prot ID | A6H7I5 |
| UniProtKB/Swiss-Prot Entry Name | DYN2_BOVIN |
| PDB IDs | Not Available |
| GenBank Gene ID | BC146259 |
| GeneCard ID | DNM2 |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| References | |
| General References | Not Available |