Identification
BMDB Protein ID BMDBP00172
Secondary Accession Numbers None
Name Tyrosine-protein kinase
Synonyms Not Available
Gene Name ITK
Protein Type Enzyme
Biological Properties
General Function Involved in ATP binding
Specific Function Not Available
Pathways Not Available
Reactions Not Available
GO Classification Not Available
Cellular Location Not Available
Gene Properties
Chromosome Location 7
Locus Not Available
SNPs ITK
Gene Sequence
>1863 bp
ATGAACAACTTTATCCTCCTGGAAGAGCAGCTCATCAAGAAATCCCAACAAAAGAGAAGA
ACTTCTCCTTCAAACTTTAAAGTCCGATTCTTTGTTTTAACCAAAACCAGCCTGGCATAC
TTTGAAGATCGTCATGGGAAAAAGCGCACTTTGAAGGGCTCCATCGAACTCTCCCGAATC
AAATGTGTCGAGATTGTGAAAAGTGACATTATCATCCCATGTCACTATAAATATCCATTT
CAGGTTGTTCACGACAACTACCTCCTGTATGTGTTTGCTCCAGACCGGGAGAGCCGGCAG
CGCTGGGTGCTGGCCCTCAAAGAAGAAACCAGGAATAACAACAGTTTGGTGCCCAAGTAT
CACCCTAATTTCTGGTTGGATGGGAGATGGCGGTGCTGTGCTCAGATGGAGAAGCTTGCA
GTGGGCTGTGCCCAGTACGATCCCACCAAAAATGCTTCAAAGAAGCCTCTTCCTCCTACT
CCTGAAGACAATAGGCGGTCACTTCGGGAACTTGAAGAAACTGTGGTCATTGCCCTGTAT
GACTACCAAACGAATGATCCACAGGAACTCATGCTACAGCGCAATGAGGAGTACTACCTG
CTCGACAGCTCTGAGATTCACTGGTGGAGGGTTCAGGACAGGAACGGGCATGAAGGATAT
GTTCCAAGCAGTTATCTGGTGGAAAAGTCTCCAAATAACCTGGAAACCTATGAGTGGTAC
AATAAGAACATCAGCCGAGACAAAGCTGAAAAACTTCTTTTGGACACAGGCAAAGAAGGA
GCCTTTATGGTGCGAGATTCCAGGACTCCAGGGACATACACCGTGTCCGTTTTCACCAAG
GCCATCGTAAGTGAGAACAACCCCTGTATAAAGCATTATCACATCAAAGAAACAAATGAC
AACCCCAAGCGATATTACGTGGCTGAAAAGTATGTGTTTGATTCCATCCCTCTCCTCATC
AATTATCACCAGCACAACGGAGGAGGCCTGGTCACTAGACTCCGGTATCCAGTTTGCTCC
TGGAGGCAGAAAGCCCCCGTCACCGCAGGGCTGAGATACGGGAAATGGGTGATTGATCCC
TCGGAGCTCACTTTTGTGCAGGAGATTGGCAGTGGGCAGTTTGGGTTGGTGCACCTTGGC
TACTGGCTCAACAAGGACAAGGTGGCCATCAAAACCATACAAGAAGGGGCTATGTCAGAA
GAGGACTTCATTGAGGAGGCTGAAGTCATGATGAAACTCTCTCACCCCAAACTAGTCCAG
CTCTATGGAGTATGCCTGGAACAGGCCCCCATCTGCCTGGTGTTTGAATTCATGGAACAC
GGCTGCCTGTCAGATTACCTGCGTAGCCAGAGGGGGCTCTTTGCTGCGGAGACCCTGCTG
GGCATGTGTCTGGACGTATGTGAGGGCATGGCCTACCTGGAAGAGGCATGTGTCATCCAC
AGAGACTTGGCTGCCCGGAATTGTTTAGTTGGGGAAAACCAAGTTATCAAGGTGTCCGAC
TTTGGGATGACAAGGTTCGTCCTTGATGACCAATACACCAGTTCCACAGGCACCAAATTC
CCAGTGAAGTGGGCATCTCCGGAAGTCTTCTCCTTCAGTCGCTACAGCAGCAAGTCAGAT
GTGTGGTCATTTGGTGTGCTGATGTGGGAAGTCTTCAGTGAAGGCAAAATCCCATACGAA
AACCGAAGCAACTCAGAGGTGGTAGAAGACATCACCACTGGATTTCGGTTATACAAGCCC
CGACTGGCCTCCCAGCATATCTACCAGATCATGAATCATTGCTGGAAAGAGAAACCAGAA
GACCGGCCACCTTTCTCCAGACTCTTGAGTCAACTGGCTGAAATTGCAGAATTGGGGCTT
TAA
Protein Properties
Number of Residues 620
Molecular Weight 72069.0
Theoretical pI 7.34
Pfam Domain Function Not Available
Signals
  • None
Transmembrane Regions Not Available
Protein Sequence
>ITK protein
MNNFILLEEQLIKKSQQKRRTSPSNFKVRFFVLTKTSLAYFEDRHGKKRTLKGSIELSRI
KCVEIVKSDIIIPCHYKYPFQVVHDNYLLYVFAPDRESRQRWVLALKEETRNNNSLVPKY
HPNFWLDGRWRCCAQMEKLAVGCAQYDPTKNASKKPLPPTPEDNRRSLRELEETVVIALY
DYQTNDPQELMLQRNEEYYLLDSSEIHWWRVQDRNGHEGYVPSSYLVEKSPNNLETYEWY
NKNISRDKAEKLLLDTGKEGAFMVRDSRTPGTYTVSVFTKAIVSENNPCIKHYHIKETND
NPKRYYVAEKYVFDSIPLLINYHQHNGGGLVTRLRYPVCSWRQKAPVTAGLRYGKWVIDP
SELTFVQEIGSGQFGLVHLGYWLNKDKVAIKTIQEGAMSEEDFIEEAEVMMKLSHPKLVQ
LYGVCLEQAPICLVFEFMEHGCLSDYLRSQRGLFAAETLLGMCLDVCEGMAYLEEACVIH
RDLAARNCLVGENQVIKVSDFGMTRFVLDDQYTSSTGTKFPVKWASPEVFSFSRYSSKSD
VWSFGVLMWEVFSEGKIPYENRSNSEVVEDITTGFRLYKPRLASQHIYQIMNHCWKEKPE
DRPPFSRLLSQLAEIAELGL
GenBank ID Protein AAI53238.1
UniProtKB/Swiss-Prot ID A7Z039
UniProtKB/Swiss-Prot Entry Name A7Z039_BOVIN
PDB IDs
GenBank Gene ID BC153237
GeneCard ID ITK
GenAtlas ID Not Available
HGNC ID Not Available
References
General References Not Available