| Identification |
|---|
| BMDB Protein ID
| BMDBP00173 |
| Secondary Accession Numbers
| None |
| Name
| Glucose-6-phosphatase 3 |
| Synonyms
|
Not Available
|
| Gene Name
| G6PC3 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in glucose-6-phosphatase activity |
| Specific Function
| Hydrolyzes glucose-6-phosphate to glucose in the endoplasmic reticulum. May form with the glucose-6-phosphate transporter (SLC37A4/G6PT) a ubiquitously expressed complex responsible for glucose production through glycogenolysis and gluconeogenesis. Probably required for normal neutrophil function (By similarity). |
| Pathways
|
- Carbohydrate biosynthesis
- Gluconeogenesis
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 19 |
| Locus
| Not Available |
| SNPs
| G6PC3 |
| Gene Sequence
|
>1041 bp
ATGGAGTCCACGCTGGGCGCGGGCATCGCGATGGCCGAGGCGCTGCAGAACCAGCTGCCC
TGGTTGGAGAACGTGTGGCTCTGGGTCACCTTTCTGGGGGACCCCAAGAGCCTCTTTCTG
TTCTACTTCCCCGCGGCCTACTATGCGTCTCGCCGGGTGGGCATTGCGGTGCTCTGGATC
AGCCTCATCACCGAGTGGCTCAACCTCGTCTTCAAGTGGTTTCTGTTTGGAGACAGGCCC
TTTTGGTGGGTCCATGAGTCTGGGTACTACAGCCAAGCTCCAGCCCAGGTTCACCAATTC
CCCTCTTCTTGTGAAACTGGCCCAGGCAGCCCTTCTGGACACTGTATGATCACAGGAGCA
GCCCTCTGGCCCATAATGACAGCCGTCTCTTCCCAGATGGCCACTCGGGCCCACAGCCGC
TGGGTGAGGGTGATTCCTAGCTTGGCTTATTGCACCTTCCTGCTGGCGGTCGGCTTATCT
CGGGTCTTCCTCTTAGCACATTTCCCTCACCAGGTGTTGGCTGGCTTAATAACTGGTGCT
GTCCTGGGCTGGCTGATGACCCCTCAGGTGCCCATGGAGCGGGAGCTAAGTTTCTATGGA
TTGACCTCACTGGCCCTCTTGCTGGGTGCCAGCCTCATCTACTGGACCCTCTTTACACTG
GGCCTGGATCTTTCTTGGTCCATCAACCTAGCCTCTAAGTGGTGTGAGCGGCCTGGGTGG
GTGCACTTGGACAGCCGGCCTTTTGCCTCCCTGAGCCGTGACTCAGGGGCCGCCCTGGGT
CTGGGCATCGCTCTGCACTCTCCCTGCTATGCCCAGGTACGGCGGGCACACCTGGGATAT
GGCCAGAAACTAGTCTGTCTTGTGCTGGCCATGGGGCTGCTGGGCCCCCTGAACTGGCTG
GGCTACCCCCCTCAGATCAGCCTTTTCTACATCTTCAATTTCCTCAAGTACACCCTCTGG
CCATGCCTGGTCCTGGCCCTCGTACCCTGGCTGGTGCACATGTTCAGTGCCCAGGAAGCA
CCACCCATCCGCTCTTCCTGA
|
| Protein Properties |
|---|
| Number of Residues
| 346 |
| Molecular Weight
| 38742.0 |
| Theoretical pI
| 8.28 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
- 25-45
- 55-75
- 109-129
- 141-162
- 168-186
- 198-218
- 255-273
- 284-304
- 308-328
|
| Protein Sequence
|
>Glucose-6-phosphatase 3
MESTLGAGIAMAEALQNQLPWLENVWLWVTFLGDPKSLFLFYFPAAYYASRRVGIAVLWI
SLITEWLNLVFKWFLFGDRPFWWVHESGYYSQAPAQVHQFPSSCETGPGSPSGHCMITGA
ALWPIMTAVSSQMATRAHSRWVRVIPSLAYCTFLLAVGLSRVFLLAHFPHQVLAGLITGA
VLGWLMTPQVPMERELSFYGLTSLALLLGASLIYWTLFTLGLDLSWSINLASKWCERPEW
VHLDSRPFASLSRDSGAALGLGIALHSPCYAQVRRAHLGYGQKLVCLVLAMGLLGPLNWL
GYPPQISLFYIFNFLKYTLWPCLVLALVPWLVHMFSAQEAPPIRSS
|
| External Links |
|---|
| GenBank ID Protein
| AAP40635.1 |
| UniProtKB/Swiss-Prot ID
| Q148G2 |
| UniProtKB/Swiss-Prot Entry Name
| G6PC3_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AY279358 |
| GeneCard ID
| G6PC3 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
