Showing Protein Putative tyrosine-protein phosphatase auxilin (BMDBP00190)
| Identification | |
|---|---|
| BMDB Protein ID | BMDBP00190 |
| Secondary Accession Numbers | None |
| Name | Putative tyrosine-protein phosphatase auxilin |
| Synonyms | Not Available |
| Gene Name | DNAJC6 |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Involved in heat shock protein binding |
| Specific Function | Recruits HSPA8/HSC70 to clathrin-coated vesicles and promotes uncoating of clathrin-coated vesicles (PubMed:15502813). Plays a role in clathrin-mediated endocytosis in neurons (By similarity). |
| Pathways | Not Available |
| Reactions | Not Available |
| GO Classification | Not Available |
| Cellular Location | Not Available |
| Gene Properties | |
| Chromosome Location | 3 |
| Locus | Not Available |
| SNPs | DNAJC6 |
| Gene Sequence |
>2733 bp ATGGACAGCTCAGGTGCCTCATCTCCAGACATGGAGCCCAGCTATGGCGGAGGTCTTTTT GACATGGTGAAAGGAGGGGCAGGGAGGCTCTTTAGCAACCTAAAGGACAACTTGAAAGAC ACTCTCAAAGACACGTCTTCCAGAGTTATACAATCTGTTACCAGCTACACGAAAGGAGAT TTAGACTTCACTTATGTTACCTCCAGAATTATTGTGATGTCCTTTCCTCTGGACAGTGTT GACATAGGATTCAGGAATCAGGTTGATGATATTCGAAGCTTTTTGGATTCCAGACATCTT GACCACTACACGGTATACAATCTGTCGCCCAAGTCTTATCGAACTGCCAAGTTTCACAGC AGGGTCTCAGAATGCAGTTGGCCCATCAGGCAGGCCCCCAGCCTGCACAACCTCTTTGCT GTGTGTCGGAATATGTATAACTGGCTACTACAGAATCCCAAAAACGTCTGTGTTGTCCAC TGCTTGGATGGACGGGCAGCATCATCGATTCTGGTTGGTGCTATGTTCATTTTCTGTAAT CTCTACTCTACTCCTGGCCCAGCCGTTCGATTGCTCTACGCAAAGCGACCAGGAATTGGA CTTTCACCATCCCACAGGAGGTACCTGGGCTACATGTGTGACCTCCTAGCAGACAAACCC TACCGCCCTCACTTCAAGCCTCTCACAATTAAGTCGATCACTGTCAGTCCAGTTCCTTTT TTCAACAAACAGAGAAATGGATGTCGCCCTTACTGCGATGTACTGATTGGAGAAACCAAA ATATATACAACCTGTGCAGATTTTGAACGAATGAAGGAATACCGTGTCCAAGATGGAAAA ATCTTCATTCCTTTGAGCATCACTGTGCAAGGAGATGTGGTTGTTTCCATGTATCACTTG AGGTCAACAATTGGAAGCAGGCTACAGGCTAAGGTGACCAACACTCAAATATTTCAGCTT CAGTTTCATACTGGATTCATTCCACTGGACACAACAGTTTTAAAGTTCACCAAGCCTGAG TTGGATGCATGTGATGTACCAGAAAAATATCCTCAGCTATTTCAGGTAACTCTGGATGTA GAACTACAGCCTCACGACAAAGTGATGGAGCTAACCCCACCGTGGGAACATTACTGCACA AAAGATGTCAACCCCAGCATCCTCTTCTCTTCTCACCAGGAGCATCAAGATACTCTGGTC TTAGGAGGACAGGCTCCAATAGATATCCCTCCAGATAATCCCAGACATTTTGGGCAAGGT GGCTTCTTTTCCACTCTCTGCTGGCAAGATCAGAAATCGGAGAAGTCATTCTGCGAGGAG GACCACGCTGCCCTAGTGAATCAGGAGAGTGAGCAGTCAGACGATGAGCTTCTGACGCTG TCCAGCCCACATGGCAATGCCAATGGTGACAAACCTCACGCAGCCAGGAAGCCCAGCAAA AAGCAGCAGGAGCCAGCTGCCCCTGCACCCCCTGAGGATGTGGATCTTCTGGGTCTAGAA GGGTCTGCTGTGAGTAAGAACTTCTCTTCGCCGGCAGCTCCTCCCTCCAATTCCGAACTT CTGAGTGACCTGTTCGGGGGCGGAGGTGCAGCCGGTCCCGTCCAGTCTGGACAGTCAGGG GTGGACGACGTGTTTCACCCGAGTGGACCTACATCCACCCAGTCCACACCACGCCGATCT GCCACCTCCACCTCTGCATCTCCAACACTGAGAGTAGGAGAAGGTGCCACCTTTGACCCA TTTGGAGCACCTTCTAAACCATCAGGTCAAGATTTGCTGGGTTCTTTTTTGAACACAGCC AGTGCTTCCAGTGACCCCTTTCTTCAGCCTACGAGGAGTCCTTCTCCTACAGTGCATGCT TCTAGTACCCCTGCTGTGAACATTCAGCCAGATGTTTCAGGAGCCTGGGACTGGCATACC AAACCAGGAGGTTTTGGAATGGGAAGCAAATCAGCTGCCACCAGCCCAACAGGCTCCTCG CATGGTACTCCCACCCATCAAAACAAACCCCAGACTCTGGACCCTTTTGCTGACCTTGGG ACATTAGGTGGTTCTTCATTTGCCAGCAAACCTTCCACACCAACTGGATTGGGTGGTGGA TTTCCACCTCTCAGCTCGCCACAGAAAGCATCTCCCCAGCCCATGGGTGGGGGGTGGCAG CAGGGAGGGGGCTACAACTGGCAGCAGACACAGTCCAAGCCACAGTCCAGCATGCCCCAC TCCTCTCCCCAGAACCGGCCCAACTACAACGTGAGCTTCTCATCCATGCCTGGGGGCCAG AACGAACGTGGGAAAGCAGCAGCTAATTTGGAGGGGAAACAAAAAGCAGCTGACTTTGAA GACCTGCTCTCTGGTCAAGGTTTTAATGCTCACAAAGACAAAAAGGGACCTCGAACAATA GCTGAGATGAGAAAGGAGGAAATGGCTAAGGAGATGGATCCTGAGAAGTTAAAGATTCTA GAATGGATTGAAGGCAAAGAGAGGAATATCAGAGCCCTTCTGTCCACAATGCACACTGTG CTGTGGGCTGGGGAGACTAAGTGGAAACCTGTTGGCATGGCAGACCTGGTCACCCCGGAG CAGGTGAAGAAGGTGTACAGGAAGGCTGTGCTAGTGGTGCACCCGGATAAAGCTACTGGG CAACCCTATGAACAATATGCAAAGATGATTTTCATGGAGCTCAATGATGCCTGGTCAGAA TTTGAAAATCAAGGCCAAAAGCCCTTGTATTAA |
| Protein Properties | |
| Number of Residues | 910 |
| Molecular Weight | 99512.0 |
| Theoretical pI | 7.27 |
| Pfam Domain Function | Not Available |
| Signals |
|
| Transmembrane Regions | Not Available |
| Protein Sequence |
>Putative tyrosine-protein phosphatase auxilin MDSSGASSPDMEPSYGGGLFDMVKGGAGRLFSNLKDNLKDTLKDTSSRVIQSVTSYTKGD LDFTYVTSRIIVMSFPLDSVDIGFRNQVDDIRSFLDSRHLDHYTVYNLSPKSYRTAKFHS RVSECSWPIRQAPSLHNLFAVCRNMYNWLLQNPKNVCVVHCLDGRAASSILVGAMFIFCN LYSTPGPAVRLLYAKRPGIGLSPSHRRYLGYMCDLLADKPYRPHFKPLTIKSITVSPVPF FNKQRNGCRPYCDVLIGETKIYTTCADFERMKEYRVQDGKIFIPLSITVQGDVVVSMYHL RSTIGSRLQAKVTNTQIFQLQFHTGFIPLDTTVLKFTKPELDACDVPEKYPQLFQVTLDV ELQPHDKVMELTPPWEHYCTKDVNPSILFSSHQEHQDTLVLGGQAPIDIPPDNPRHFGQG GFFSTLCWQDQKSEKSFCEEDHAALVNQESEQSDDELLTLSSPHGNANGDKPHAARKPSK KQQEPAAPAPPEDVDLLGLEGSAVSKNFSSPAAPPSNSELLSDLFGGGGAAGPVQSGQSG VDDVFHPSGPTSTQSTPRRSATSTSASPTLRVGEGATFDPFGAPSKPSGQDLLGSFLNTA SASSDPFLQPTRSPSPTVHASSTPAVNIQPDVSGAWDWHTKPGGFGMGSKSAATSPTGSS HGTPTHQNKPQTLDPFADLGTLGGSSFASKPSTPTGLGGGFPPLSSPQKASPQPMGGGWQ QGGGYNWQQTQSKPQSSMPHSSPQNRPNYNVSFSSMPGGQNERGKAAANLEGKQKAADFE DLLSGQGFNAHKDKKGPRTIAEMRKEEMAKEMDPEKLKILEWIEGKERNIRALLSTMHTV LWAGETKWKPVGMADLVTPEQVKKVYRKAVLVVHPDKATGQPYEQYAKMIFMELNDAWSE FENQGQKPLY |
| External Links | |
| GenBank ID Protein | AAA79037.1 |
| UniProtKB/Swiss-Prot ID | Q27974 |
| UniProtKB/Swiss-Prot Entry Name | AUXI_BOVIN |
| PDB IDs | |
| GenBank Gene ID | U09237 |
| GeneCard ID | DNAJC6 |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| References | |
| General References | Not Available |