| Identification |
|---|
| BMDB Protein ID
| BMDBP00210 |
| Secondary Accession Numbers
| None |
| Name
| Enolase-phosphatase E1 |
| Synonyms
|
Not Available
|
| Gene Name
| ENOPH1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Energy production and conversion |
| Specific Function
| Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). |
| Pathways
|
- Amino-acid biosynthesis
- L-methionine biosynthesis via salvage pathway
- L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 3/6
- L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 4/6
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 6 |
| Locus
| Not Available |
| SNPs
| ENOPH1 |
| Gene Sequence
|
>786 bp
ATGGTCGTGCTTTCGGTGCCCGCCGAAGTCACTGTGATCCTGTTAGATATCGAAGGTACC
ACAACCCCGATTGCTTTCGTGAAGGACATTTTATTTCCTTACGTCAAAGAAAATGTTGAA
GAGTATCTGCAGGCACATTGGGAAGAAGAGGAGTGCCAACAGGATGTCAGGCTTTTGAGG
AAACAGGCTGAAGAGGACTCCCACCTGGATGGGGCTGTTCCAATCCCAGCAGCCTCCGGT
AATGGGGCGGACGACCCGCAGTGGATGATCCAGGCCGTGGTGGATAACGTGTACTGGCAG
ATGTCCCTGGACCGGAAGACCACGGCACTGAAGCAGCTGCAGGGCCACATGTGGAGGGCG
GCGTTCAAGGCTGGGCACATGAAAGCGGAGTTCTTTGAAGACGTGGTTCCGGCCGTCCGG
AAGTGGCGAGAGGCTGGGATGAAGGTGTATGTCTATTCTTCAGGGAGTGTGGAGGCGCAG
AAACTATTATTTGGGCATTCTACAGAGGGGGACATTCTTGAGCTTGTGGATGGTCACTTT
GATACCAAGATTGGACACAAAGTGGAGAGTGAGAGTTACCAAAAGATCGCCAGCAGCATT
GGCTGTTCAACCAACAACATCTTGTTTCTGACGGATGTTTCCCGAGAGGCCAGCGCTGCT
GAGGAGGCGGGCGTGCATGTCGCTGTGGTGGTGAGACCGGGCAACGCAGGGCTGACTGAT
GATGAGAAGACCCACTTCAGCCTCATCACGTCCTTCAGTGAACTGTACCTGCCTTCCTCA
ACCTAG
|
| Protein Properties |
|---|
| Number of Residues
| 261 |
| Molecular Weight
| 28930.0 |
| Theoretical pI
| 4.56 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Enolase-phosphatase E1
MVVLSVPAEVTVILLDIEGTTTPIAFVKDILFPYVKENVEEYLQAHWEEEECQQDVRLLR
KQAEEDSHLDGAVPIPAASGNGADDPQWMIQAVVDNVYWQMSLDRKTTALKQLQGHMWRA
AFKAGHMKAEFFEDVVPAVRKWREAGMKVYVYSSGSVEAQKLLFGHSTEGDILELVDGHF
DTKIGHKVESESYQKIASSIGCSTNNILFLTDVSREASAAEEAGVHVAVVVRPGNAGLTD
DEKTHFSLITSFSELYLPSST
|
| External Links |
|---|
| GenBank ID Protein
| AAI19872.1 |
| UniProtKB/Swiss-Prot ID
| Q0VD27 |
| UniProtKB/Swiss-Prot Entry Name
| ENOPH_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC119871 |
| GeneCard ID
| ENOPH1 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
