Showing Protein Pyridoxal phosphate phosphatase (BMDBP00216)
| Identification | |||||
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| BMDB Protein ID | BMDBP00216 | ||||
| Secondary Accession Numbers | None | ||||
| Name | Pyridoxal phosphate phosphatase | ||||
| Synonyms | Not Available | ||||
| Gene Name | PDXP | ||||
| Protein Type | Enzyme | ||||
| Biological Properties | |||||
| General Function | Carbohydrate transport and metabolism | ||||
| Specific Function | Protein serine phosphatase that dephosphorylates 'Ser-3' in cofilin and probably also dephosphorylates phospho-serine residues in DSTN. Regulates cofilin-dependent actin cytoskeleton reorganization. Required for normal progress through mitosis and normal cytokinesis. Does not dephosphorylate phospho-threonines in LIMK1. Does not dephosphorylate peptides containing phospho-tyrosine (PubMed:15580268). Pyridoxal phosphate (PLP) phosphatase, which also catalyzes the dephosphorylation of pyridoxine 5'-phosphate (PNP) and pyridoxamine 5'-phosphate (PMP), with order of substrate preference PLP > PNP > PMP (By similarity). | ||||
| Pathways |
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| Reactions |
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| GO Classification | Not Available | ||||
| Cellular Location | Not Available | ||||
| Gene Properties | |||||
| Chromosome Location | 5 | ||||
| Locus | Not Available | ||||
| SNPs | PDXP | ||||
| Gene Sequence |
>891 bp ATGGCGCGCTGCGAGCGGCTGCGCGGCGCGGCCCTGCGCGACGTGGTGGGCCGGGCGCAG GGGGTCCTGTTCGACTGCAACGGGGTGCTGTGGAACGGCGAGCGCGCAGTGCCGGGCGCC CCCGAGCTCCTGGAGAGACTGGCTCAGGCTGGCAAGGCGACGCTCTTCGTGAGCAACAAC AGCCGGCGCGCGCGGCCCGAGCTGGCCCTCCGCTTCGCGCGACTTGGCTTCGGGGGGCTG CGCTCCGAGCAGCTCTTCAGCTCCGCGCTGTGCGCCGCGCGCTTGCTGCGCCAGCGCCTG CTCGGACCTCCGGACACTCAGGGCGCGGTGTTCGTGCTGGGCGGTGAAGGGCTGCGGGCC GAGCTGCGCGCCGCCGGGCTGCGCCTGGCGGGGGACCCCAGCGAGGACCCGGGCGCGGCC CCGCGCGTGCGCGCCGTGCTTGTGGGCTACGACGAGCACTTCTCCTTCGCCAAGCTGAGC GAGGCCTGCGCGCACTTGCGCGACCCCGACTGCCTGCTGGTAGCCACCGACCGCGACCCG TGGCACCCTCTCAGCGACGGCAGCCGGACCCCCGGCACCGGGAGCTTGGCTGCTGCTGTG GAGACAGCCTCGGGCCGCCAGGCCCTGGTGGTGGGCAAGCCCAGCCCCTACATGTTCGAG TGCATCACAGAGCACTTCAGCGTGGACCCCGGCCGCACGCTGATGGTGGGCGACCGCCTG GAGACTGACATCCTCTTCGGCCACCGCTGTGGTATGACCACCGTGCTCACGCTCACGGGC GTCTCCAGCCTGGAGGAGGCCCAGGCCTACCTGGCGGCCGGCCAGCACGACCTCGTGCCC CATTACTACGTGGAGAGCATCGCGGACTTGATGGAGGGGTTGGAGGACTGA |
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| Protein Properties | |||||
| Number of Residues | 296 | ||||
| Molecular Weight | 31749.0 | ||||
| Theoretical pI | 5.91 | ||||
| Pfam Domain Function | Not Available | ||||
| Signals |
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| Transmembrane Regions | Not Available | ||||
| Protein Sequence |
>Pyridoxal phosphate phosphatase MARCERLRGAALRDVVGRAQGVLFDCNGVLWNGERAVPGAPELLERLAQAGKATLFVSNN SRRARPELALRFARLGFGGLRSEQLFSSALCAARLLRQRLLGPPDTQGAVFVLGGEGLRA ELRAAGLRLAGDPSEDPGAAPRVRAVLVGYDEHFSFAKLSEACAHLRDPDCLLVATDRDP WHPLSDGSRTPGTGSLAAAVETASGRQALVVGKPSPYMFECITEHFSVDPGRTLMVGDRL ETDILFGHRCGMTTVLTLTGVSSLEEAQAYLAAGQHDLVPHYYVESIADLMEGLED |
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| External Links | |||||
| GenBank ID Protein | AAI03330.1 | ||||
| UniProtKB/Swiss-Prot ID | Q3ZBF9 | ||||
| UniProtKB/Swiss-Prot Entry Name | PLPP_BOVIN | ||||
| PDB IDs | Not Available | ||||
| GenBank Gene ID | BC103329 | ||||
| GeneCard ID | PDXP | ||||
| GenAtlas ID | Not Available | ||||
| HGNC ID | Not Available | ||||
| References | |||||
| General References | Not Available | ||||