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| Identification |
|---|
| BMDB Protein ID
| BMDBP00227 |
| Secondary Accession Numbers
| |
| Name
| Branched-chain-amino-acid aminotransferase, mitochondrial |
| Synonyms
|
Not Available
|
| Gene Name
| BCAT2 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Amino acid transport and metabolism |
| Specific Function
| Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine. May also function as a transporter of branched chain alpha-keto acids (By similarity). |
| Pathways
|
Not Available
|
| Reactions
|
| L-Valine + Oxoglutaric acid → Alpha-ketoisovaleric acid + L-Glutamic acid |
details
|
| L-Leucine + Oxoglutaric acid → Ketoleucine + L-Glutamic acid |
details
|
| L-Isoleucine + Oxoglutaric acid → 3-Methyl-2-oxovaleric acid + L-Glutamic acid |
details
|
|
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 18 |
| Locus
| 18q24 |
| SNPs
| BCAT2 |
| Gene Sequence
|
>1182 bp
ATGGCTACAGCGGCATTGAGGCAGATTTGGATCCCCAGATTTCTCCCTGTTCCTTGGTTT
CTGTGTGGTTCCAGAAGATATGCCTCATCCAGCTTCAAGGCTGCTGACCTGCAGCTGGAA
ATGACACAGGAGCCTCATAAGAAGCCTGACCCCAGCCAGCCTCTGCTGTTCGGGAAGACA
TTCACCGACCACATGCTGATGGTGGAATGGAATCAGGAGAAGGGCTGGGGCCAGCCCCGA
ATCCAGCCCTTCCAGAACCTCACGCTGCACCCGGCCTGCTCCGCTCTGCACTACTCCCTG
CAGCTCTTTGAAGGCATGAAGGCATTCAAAGGTGGGGACCAGCGCGTGCGCCTCTTCCGA
CCTTGGCTCAACATGGAACGGATGCTGCGCTCGGCCCTCCGCCTCTGCCTACCGAGTTTC
GACAAAATTGAGTTGCTGGAGTGCATCCGCCGGCTGGTGGAAGTGGACCAGGACTGGGTC
CCTGGCAGCATGGGCACTAGCCTCTACGTTCGGCCCGTGTTGATCGGGAACGAGCCCTCG
CTAGGTGTCGGCCACCCTACTCGAGCCCTCCTGTTCGTCATTCTCAGCCCTGTGGGCGCC
TACTTCCCTGGAGATGCCTTGAAACCTGTCTCCCTCCTGGCAGATCCATCATTCATCCGG
GCCTGGGTGGGTGGGGTCGGCAACTACAAGCTGGGAGGGAATTACGGGCCCACCGTGTTA
GTGCAGCAGGAGGCACAAAAGAAGGGCTGCGAGCAGGTCCTCTGGCTGTATGGGCCTGAT
CACGAGCTCACGGAGGTGGGCACCATGAACATCTTCGTCTTCTGGACCTATGAGGACGGG
GTGCTGGAACTGGTGACCCCCCCACTGGACGGCATCATCCTACCTGGAATAGTCCGACAG
AGTCTGCTGGACCTGGCCCGGACCTGGGGTGAATTCCGAGTGGTAGAGCGTAAGATTACC
ATGAAGGAGTTCCTGCGGGCGCTGAAGGATGGCCGGGTCCGAGAAGTCTTCGGTTCAGGC
ACTGCTTGCCAGGTCTGCCCCGTGCACCAAATCCTGTACCAAGGCAAGCATTTCCACATT
CCCACCATGGAAAACGGGCCCCAGCTCATCCTCCGCTTCCACAAGGAACTGAAGGCGATC
CAGTACGGATCAAAAGCCCATGAATGGATGCTCCCGGTGTAA
|
| Protein Properties |
|---|
| Number of Residues
| 393 |
| Molecular Weight
| 44648.0 |
| Theoretical pI
| 8.82 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Branched-chain-amino-acid aminotransferase, mitochondrial
MATAALRQIWIPRFLPVPWFLCGSRRYASSSFKAADLQLEMTQEPHKKPDPSQPLLFGKT
FTDHMLMVEWNQEKGWGQPRIQPFQNLTLHPACSALHYSLQLFEGMKAFKGGDQRVRLFR
PWLNMERMLRSALRLCLPSFDKIELLECIRRLVEVDQDWVPGSMGTSLYVRPVLIGNEPS
LGVGHPTRALLFVILSPVGAYFPGDALKPVSLLADPSFIRAWVGGVGNYKLGGNYGPTVL
VQQEAQKKGCEQVLWLYGPDHELTEVGTMNIFVFWTYEDGVLELVTPPLDGIILPGIVRQ
SLLDLARTWGEFRVVERKITMKEFLRALKDGRVREVFGSGTACQVCPVHQILYQGKHFHI
PTMENGPQLILRFHKELKAIQYGSKAHEWMLPV
|
| External Links |
|---|
| GenBank ID Protein
| AAX08746.1 |
| UniProtKB/Swiss-Prot ID
| Q5EA40 |
| UniProtKB/Swiss-Prot Entry Name
| BCAT2_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BT020729 |
| GeneCard ID
| BCAT2 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
