Identification
BMDB Protein ID BMDBP00232
Secondary Accession Numbers None
Name Coagulation factor XI
Synonyms Not Available
Gene Name F11
Protein Type Enzyme
Biological Properties
General Function Involved in heparin binding
Specific Function Factor XI triggers the middle phase of the intrinsic pathway of blood coagulation by activating factor IX.
Pathways
  • Coagulation
Reactions
Coagulation factor IX → Coagulation factor IXa details
GO Classification Not Available
Cellular Location Not Available
Gene Properties
Chromosome Location 27
Locus Not Available
SNPs F11
Gene Sequence
>1878 bp
ATGACTTTATTATATCAAATGGTACATTTCGCTTTATTTGCCTCCGTTGCTGGTGAGTGT
GTGACCACGCTGTTCCAAGATGCCTGCTTTAAAGGAGGAGACATCACTGTGGCTTTCGCG
CCAAATGCCAAGCACTGCCAAATCATCTGCACCCACCACCCAAGGTGCTTGCTCTTCACT
TTTATGACTGAATCATCATCAGAAGATCCTACCAAGTGGTATACTTGCATCCTGAAAGAC
AGTGTTACAGAAACACTGCCAATGGTGAATATGACAGGAGCAATTTCTGGATATTCTTCC
AAGCAATGCTTGCACCACATAAGTGCTTGCAGCAAAGACATGTATGTGGACCTAAACATG
AAGGGGATGAACTATAACAGCTCCCTTGCCCAGAGCGCTCGGGAATGCCAACAGAGGTGT
ACAGACGACACGCACTGCCATTTTTTTACATTCGCCACAAGGCACTTTCCAAGCATAAAG
GATCGTAACACTTGTCTGTTGAAGAACACCCAAACAGGGACACCAACCAGCATAACGAAG
CTCCACGAAGTGGTATCTGGATTTTCTTTGAAGTCCTGTGGCCTTTCTAACCTGGCTTGT
ATTAGGGACATTTTCCCCAGAACCGCGTTTGTGGACATCACCATTGACACTGTCATGGCC
CCAGATCCCTTTGTCTGTCGCAGCATCTGTACTCACCATCCCAGTTGTCTGTTTTTTACC
TTCTTGTCTGAAGAATGGCCAACAGCATCTGAAAGAAATCTGTGTCTCCTTAAAACATCT
TCAAGTGGATTGCCAAGCGCACGCTTTAGAAAGAACAGAGCTTTTTCTGGTTTTAGTCTA
CAACACTGCCAGCACAGTGTCCCAGTGTTCTGCCATTCTTCATTCTATCGCAACACTGAT
TTCTTGGGAGAAGAACTGGACATCGTAGACGCGGACAGCCACGAAGCCTGCCAGAAAACA
TGTACCAACAGCATCCGCTGCCAGTTCTTTACCTATTCTCCATCTCAAGAATCGTGCAAC
GGAGGGAAGGGTAAATGCTACTTAAAACTTTCTGCAAATGGATCTCCAACTAAAATACTT
CATGGGACAGGAAGCATCTCTGGATACACGTTAAGGTTATGTAAAATGGATAATGTGTGT
ACAACCAAAATCAAGACCAGAATTGTAGGAGGAACCCAGTCTGTTCACGGAGAGTGGCCG
TGGCAGATAACTCTGCACGTGACATCACCCACCCAGAGACACCTGTGTGGAGGCGCCATC
ATCGGAAACCAGTGGATATTAACAGCTGCTCACTGTTTCAACGAGGTCAAGTCACCTAAT
GTGTTGCGTGTCTATAGCGGCATTTTGAATCAATCAGAAATAAAAGAGGATACATCTTTC
TTTGGGGTTCAAGAAATAATAATTCATGATCAATATGAAAAGGCAGAAAGTGGATATGAC
ATTGCCTTGTTGAAACTAGAAACGGCAATGAATTATACAGACTCTCAATGGCCCATATGC
CTACCTTCCAAAGGAGATAGAAATGTAATGTATACTGAATGCTGGGTGACCGGATGGGGA
TACAGAAAATTAAGAGACAAAATACAGAATACTCTCCAGAAAGCCAAGGTACCCTTGATG
ACCAATGAAGAATGCCAGGCAGGTTACAGAGAGCACAGAATAACCAGCAAGATGGTCTGT
GCAGGCTACAGAGAAGGAGGGAAGGACGCCTGTAAGGGGGATTCAGGGGGGCCCCTGTCC
TGTAAGCACAACGAGGTGTGGCACCTGGTAGGCATCACGAGCTGGGGTGAAGGCTGCGGC
CAAAGGGAGCGGCCAGGTGTTTACAGCAACGTGGTCGAGTATGTGGACTGGATTCTGGAG
AAAACGCAAGGCCCTTGA
Protein Properties
Number of Residues 625
Molecular Weight 69872.0
Theoretical pI 7.65
Pfam Domain Function Not Available
Signals
  • 1-18
Transmembrane Regions Not Available
Protein Sequence
>Coagulation factor XI
MTLLYQMVHFALFASVAGECVTTLFQDACFKGGDITVAFAPNAKHCQIICTHHPRCLLFT
FMTESSSEDPTKWYTCILKDSVTETLPMVNMTGAISGYSSKQCLHHISACSKDMYVDLNM
KGMNYNSSLAQSARECQQRCTDDTHCHFFTFATRHFPSIKDRNTCLLKNTQTGTPTSITK
LHEVVSGFSLKSCGLSNLACIRDIFPRTAFVDITIDTVMAPDPFVCRSICTHHPSCLFFT
FLSEEWPTASERNLCLLKTSSSGLPSARFRKNRAFSGFSLQHCQHSVPVFCHSSFYRNTD
FLGEELDIVDADSHEACQKTCTNSIRCQFFTYSPSQESCNGGKGKCYLKLSANGSPTKIL
HGTGSISGYTLRLCKMDNVCTTKIKTRIVGGTQSVHGEWPWQITLHVTSPTQRHLCGGAI
IGNQWILTAAHCFNEVKSPNVLRVYSGILNQSEIKEDTSFFGVQEIIIHDQYEKAESGYD
IALLKLETAMNYTDSQWPICLPSKGDRNVMYTECWVTGWGYRKLRDKIQNTLQKAKVPLM
TNEECQAGYREHRITSKMVCAGYREGGKDACKGDSGGPLSCKHNEVWHLVGITSWGEGCG
QRERPGVYSNVVEYVDWILEKTQGP
GenBank ID Protein BAD77921.1
UniProtKB/Swiss-Prot ID Q5NTB3
UniProtKB/Swiss-Prot Entry Name FA11_BOVIN
PDB IDs Not Available
GenBank Gene ID AB196307
GeneCard ID F11
GenAtlas ID Not Available
HGNC ID Not Available
References
General References Not Available