| Identification |
|---|
| BMDB Protein ID
| BMDBP00238 |
| Secondary Accession Numbers
| None |
| Name
| Argininosuccinate lyase |
| Synonyms
|
Not Available
|
| Gene Name
| ASL |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Amino acid transport and metabolism |
| Specific Function
| Not Available |
| Pathways
|
- Amino-acid biosynthesis
- Arginine and Proline Metabolism
- Aspartate Metabolism
- L-arginine and fumarate from (N(omega)-L-arginino)succinate: step 1/1
- L-arginine biosynthesis
- L-arginine from L-ornithine and carbamoyl phosphate: step 3/3.
- Nitrogen metabolism
- Urea Cycle
|
| Reactions
|
| 2 Argininosuccinic acid → Fumaric acid + L-Arginine |
details
|
|
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 25 |
| Locus
| Not Available |
| SNPs
| ASL |
| Gene Sequence
|
>1422 bp
ATGGCATCGGAGAGCGGGAAGCTATGGGGTGGCCGGTTTGTGGGCACAGTGGACCCCATC
ATGGAAAAGTTCAACTCGTCCATCACGTACGACCGGCACCTCTGGGAGGCGGACGTGCAG
GGCAGCAAAGCCTACAGCCGGGGCCTGGAGAAGGCGGGGCTCCTCACCAAAGCCGAGATG
GACCAGATACTCCATGGCCTGGACAAGGTAGCTGAGGAGTGGGCTCAGGGCACCTTCAAA
CTAAACCCCAATGATGAGGACATCCATACGGCCAATGAGCGGCGTCTGAAGGAGCTCATT
GGTGAAACCGCGGGGAAGCTGCACACGGGACGAAGTCGGAACGACCAGGTGGTCACTGAC
CTCAGGCTGTGGATGCGGCAGAATTGCTCCATGCTCTCAGCCCTCCTCTGCGAACTCATC
AGAACCATGGTGGATCGGGCAGAGGCGGAACGTGATGTCCTCTTCCCAGGGTACACACAC
CTGCAGAGGGCTCAGCCGATCCGCTGGAGCCACTGGATCCTGAGCCATGCGGTGGCTCTG
ACCAGAGACTCTGAAAGGCTGCTGGAGGTGCGGAAGCGGATCAACGTCCTGCCCCTGGGG
AGCGGGGCCATCGCAGGCAACCCCCTGGGTGTGGACCGGGAACTGCTCCGAGCAGAACTG
GACTTTGGGGCCATCACTCTCAACAGCATGGATGCCACCAGTGAGCGAGACTTTGTGGCC
GAGTTCCTATTCTGGGCTTCGCTGTGCATGACCCACCTCAGCAGGATGGCTGAGGATCTC
ATCCTCTATGGCACCAAGGAGTTCAGCTTCGTGCAGCTCTCAGATGCCTACAGCACCGGA
AGCAGTCTGATGCCCCAGAAGAAAAACCCAGACAGCCTGGAGCTGATCCGGAGCAAGGCG
GGGCGAGTGTTTGGGCGGTGTGCTGGGCTCCTGATGACACTCAAGGGACTTCCGAGCACC
TACAACAAGGACTTACAGGAAGACAAGGAAGCCGTGTTTGAAGTGTCCGACACCATGAGC
GCTGTCCTCCAAGTGGCCACTGGTGTCATCTCTACCCTGCAGATTCACCGTGAGAACATG
GGACGGGCTCTGAGTCCTGACATGCTAGCCACTGACCTCGCCTACTACCTGGTCCGAAAA
GGGATGCCATTCCGCCAGGCCCACGAGGCCTCCGGGAAAGCCGTGTTCATGGCTGAGACC
AAGGGGGTCGCCCTCAATCAGCTGTCACTGCAGGAGCTGCAGACCATCAGCCCCCTGTTC
TCGGGCGACGTGAGCCACGTGTGGGACTACGGACACAGCGTGGAGCAGTACGAGGCCCTG
GGAGGCACCGCGCGCTCCAGCGTTGACTGGCAGATCGGCCAGCTGCGAGCTCTCCTCCGG
GCACAGCAGACCGAGAGCCCTCCCCACGCCTCTCCCAAATAA
|
| Protein Properties |
|---|
| Number of Residues
| 473 |
| Molecular Weight
| 52743.0 |
| Theoretical pI
| 6.46 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Argininosuccinate lyase
MASESGKLWGGRFVGTVDPIMEKFNSSITYDRHLWEADVQGSKAYSRGLEKAGLLTKAEM
DQILHGLDKVAEEWAQGTFKLNPNDEDIHTANERRLKELIGETAGKLHTGRSRNDQVVTD
LRLWMRQNCSMLSALLCELIRTMVDRAEAERDVLFPGYTHLQRAQPIRWSHWILSHAVAL
TRDSERLLEVRKRINVLPLGSGAIAGNPLGVDRELLRAELDFGAITLNSMDATSERDFVA
EFLFWASLCMTHLSRMAEDLILYGTKEFSFVQLSDAYSTGSSLMPQKKNPDSLELIRSKA
GRVFGRCAGLLMTLKGLPSTYNKDLQEDKEAVFEVSDTMSAVLQVATGVISTLQIHRENM
GRALSPDMLATDLAYYLVRKGMPFRQAHEASGKAVFMAETKGVALNQLSLQELQTISPLF
SGDVSHVWDYGHSVEQYEALGGTARSSVDWQIGQLRALLRAQQTESPPHASPK
|
| External Links |
|---|
| GenBank ID Protein
| AAI02832.1 |
| UniProtKB/Swiss-Prot ID
| Q3SZJ0 |
| UniProtKB/Swiss-Prot Entry Name
| ARLY_BOVIN |
| PDB IDs
|
|
| GenBank Gene ID
| BC102831 |
| GeneCard ID
| ASL |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
