Showing Protein Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial (BMDBP00239)
| Identification | |||||||
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| BMDB Protein ID | BMDBP00239 | ||||||
| Secondary Accession Numbers |
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| Name | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | ||||||
| Synonyms | Not Available | ||||||
| Gene Name | AADAT | ||||||
| Protein Type | Enzyme | ||||||
| Biological Properties | |||||||
| General Function | Transcription | ||||||
| Specific Function | Transaminase with broad substrate specificity. Has transaminase activity towards aminoadipate, kynurenine, methionine and glutamate. Shows activity also towards tryptophan, aspartate and hydroxykynurenine. Accepts a variety of oxo-acids as amino-group acceptors, with a preference for 2-oxoglutarate, 2-oxocaproic acid, phenylpyruvate and alpha-oxo-gamma-methiol butyric acid. Can also use glyoxylate as amino-group acceptor (in vitro) (By similarity). | ||||||
| Pathways |
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| Reactions |
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| GO Classification | Not Available | ||||||
| Cellular Location | Not Available | ||||||
| Gene Properties | |||||||
| Chromosome Location | 8 | ||||||
| Locus | Not Available | ||||||
| SNPs | AADAT | ||||||
| Gene Sequence |
>1278 bp ATGAATTACGCTCGGTTCATTACCGCCACGAGCGCGGCCAGAAAGCCTTCTACCATCCGA GTCATGACTGAAATATTGAGCAAGGCACCGAAATCTGTCATCTCCTTGGCAACTGGGGCA CCAAACCCCAACACGTTCCCTTTCAAGACTGCGGTCATCACCATAGAAAACGGAAAACCC ATCCAATTTAATGAACAGATGATGAAGAGAGCACTGCAGTATTCTCAGAGTGCTGGAATC CCAGAGCTGTTATCCTGGCTAAAACAGTTACAAGTAAAATTGCATAATCCGCCCACCATC CATTATGCACCCACCCAAGGACAGATGGACTTATGTGTCACATGTGGCAGCCAAGAAGGT CTCTGTAAGGTATTTGAAATGATCGTTAATCCTGGAGATAATATCCTTGTAAATGAACCT ATTTATTCAGGAACAATTCATGCTCTGCAACCCCTGGGCTGCAACATGATTAATGTTTCC AGTGATGAGCACGGGATTATTCCAGACTCCCTCAGAGAAATACTTTCCAAATGGAAACCA GAAGATTCAAAGAACCCCAAGAAAAACAGCCCCAAATTTCTTTACACTGTCCCAAATGGC AACAACCCCTCTGGGAACTCATTAACAGCTGAGCGCAAAAGGGAAATCTATGAGCTCGCA AGAAAATATGACTTCCTCATCATAGAAGATGATCCTTACTATTTTATGCAGTTCAACAAG CCCTGGGCACCGACATTTCTCTCCATGGACGAGGATGGGCGCGTCATCCGAGCTGACTCT TTTTCCAAAGTCCTGTCCTCAGGGTTGAGAATAGGGTTTATAACTGGTCCAAAGCCCTTG ATTGAGAGAATTGTTTTACACATACAAGTTTCAACAATGCACCCCAGCACTTTTGCTCAG CTCCTGGTATCACAGCTTCTATACCAATGGGGAGAAGAGGGCTTCCTGGGTCACGTAGAC AGGGTTATTGATTTCTACAGGAAGCAGAGGGATGCATTAATGGCAGCAGCAGACAAGTGG TTAAGTGGTTTGGCAGAATGGCATGTTCCTACTGCAGGAATGTTTCTATGGGTTAAAATT AAGGGCATTCATGATGTAAGAAAACTGATCGAAGAAAAAGCCTTTAAGAAAGAGATATTC ATGCTTCCGGGATGTGGTTTCTACACTGACAGTTCAGCTCCTTGCCCGTACTTCAGAGCA TCCTTCTCTTCAGCTTCTCCAGAACAGATGGACTTGGCCTTTCAGAGACTGGCCCAACTT ATAAAAGAATCTTTATGA |
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| Protein Properties | |||||||
| Number of Residues | 425 | ||||||
| Molecular Weight | 47901.0 | ||||||
| Theoretical pI | 8.72 | ||||||
| Pfam Domain Function | Not Available | ||||||
| Signals |
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| Transmembrane Regions | Not Available | ||||||
| Protein Sequence |
>Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial MNYARFITATSAARKPSTIRVMTEILSKAPKSVISLATGAPNPNTFPFKTAVITIENGKP IQFNEQMMKRALQYSQSAGIPELLSWLKQLQVKLHNPPTIHYAPTQGQMDLCVTCGSQEG LCKVFEMIVNPGDNILVNEPIYSGTIHALQPLGCNMINVSSDEHGIIPDSLREILSKWKP EDSKNPKKNSPKFLYTVPNGNNPSGNSLTAERKREIYELARKYDFLIIEDDPYYFMQFNK PWAPTFLSMDEDGRVIRADSFSKVLSSGLRIGFITGPKPLIERIVLHIQVSTMHPSTFAQ LLVSQLLYQWGEEGFLGHVDRVIDFYRKQRDALMAAADKWLSGLAEWHVPTAGMFLWVKI KGIHDVRKLIEEKAFKKEIFMLPGCGFYTDSSAPCPYFRASFSSASPEQMDLAFQRLAQL IKESL |
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| External Links | |||||||
| GenBank ID Protein | AAX08861.1 | ||||||
| UniProtKB/Swiss-Prot ID | Q5E9N4 | ||||||
| UniProtKB/Swiss-Prot Entry Name | AADAT_BOVIN | ||||||
| PDB IDs | Not Available | ||||||
| GenBank Gene ID | BT020844 | ||||||
| GeneCard ID | AADAT | ||||||
| GenAtlas ID | Not Available | ||||||
| HGNC ID | Not Available | ||||||
| References | |||||||
| General References | Not Available | ||||||