Showing Protein Probable palmitoyltransferase ZDHHC21 (BMDBP00249)
| Identification | |
|---|---|
| BMDB Protein ID | BMDBP00249 |
| Secondary Accession Numbers | None |
| Name | Probable palmitoyltransferase ZDHHC21 |
| Synonyms | Not Available |
| Gene Name | ZDHHC21 |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Involved in zinc ion binding |
| Specific Function | Palmitoylates sex steroid hormone receptors, including ESR1, PGR and AR, thereby regulating their targeting to the plasma membrane. This affects rapid intracellular signaling by sex hormones via ERK and AKT kinases and the generation of cAMP, but does not affect that mediated by their nuclear receptor (By similarity). |
| Pathways | Not Available |
| Reactions | Not Available |
| GO Classification | Not Available |
| Cellular Location | Not Available |
| Gene Properties | |
| Chromosome Location | 8 |
| Locus | Not Available |
| SNPs | ZDHHC21 |
| Gene Sequence |
>798 bp ATGGGTCTCCGGATTCACTTTGTTGTTGACCCACATGGTTGGTGCTGCATGGGTTTGATT GTCTTTGTCTGGTTATACAACTTTTTTTTAATTCCTAAGATTGTCCTCTTTCCTCACTAT GAAGAAGGACATATTCCAGGCATATTAATAATAATATTCTATGGCATTGCCATGTTTTGT CTGGTTGCTTTAGTGAGGGCCTCAATAACTGATCCAGGAAGACTCCCTGAGAACCCAAAG ATCCCACATGGAGAAAGGGAGTTCTGGGAATTGTGTAACAAGTGTAATTTGATGAGACCG AAGCGTTCCCATCACTGCAGCCGCTGCGGCCACTGTGTTAGGAGAATGGATCATCACTGC CCATGGATTAACAATTGTGTTGGTGAAGATAACCATTGGCTTTTTCTGCAATTGTGTTTC TACACTGAACTTCTTACTTGCTACGCACTGATGTTTTCTTTCTGCCACTATTATTACTTT CTTCCGCTAAAAAAGCGTAATTTGGACCTCTTTGTTGTCAGACATGAATTGGCCATAATG AGACTAGCTGCCTTTATGGGCATTACAATGTTAGTTGGAATAACTGGACTGTTTTATACT CAACTAATTGGCATCATCACAGATACAACATCTATTGAAAAGATGTCAAACTGTTGTGAA GAAATATCGAGGCCCCGAAAGCCATGGCAGCAGACCTTCTCAGAAGTTTTTGGCACTCGT TGGAAGATCCTGTGGTTTATTCCTTTCAGGCGGAGGCAACCACTGCGAGTTCCCTACCAC TTTGCCAATCACGTCTAA |
| Protein Properties | |
| Number of Residues | 265 |
| Molecular Weight | 31463.0 |
| Theoretical pI | 8.59 |
| Pfam Domain Function | Not Available |
| Signals |
|
| Transmembrane Regions |
|
| Protein Sequence |
>Probable palmitoyltransferase ZDHHC21 MGLRIHFVVDPHGWCCMGLIVFVWLYNFFLIPKIVLFPHYEEGHIPGILIIIFYGIAMFC LVALVRASITDPGRLPENPKIPHGEREFWELCNKCNLMRPKRSHHCSRCGHCVRRMDHHC PWINNCVGEDNHWLFLQLCFYTELLTCYALMFSFCHYYYFLPLKKRNLDLFVVRHELAIM RLAAFMGITMLVGITGLFYTQLIGIITDTTSIEKMSNCCEEISRPRKPWQQTFSEVFGTR WKILWFIPFRRRQPLRVPYHFANHV |
| External Links | |
| GenBank ID Protein | AAI33396.1 |
| UniProtKB/Swiss-Prot ID | A2VDT6 |
| UniProtKB/Swiss-Prot Entry Name | ZDH21_BOVIN |
| PDB IDs | Not Available |
| GenBank Gene ID | BC133395 |
| GeneCard ID | ZDHHC21 |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| References | |
| General References | Not Available |