Showing Protein Palmitoyltransferase ZDHHC20 (BMDBP00250)
| Identification | |
|---|---|
| BMDB Protein ID | BMDBP00250 |
| Secondary Accession Numbers | None |
| Name | Palmitoyltransferase ZDHHC20 |
| Synonyms | Not Available |
| Gene Name | ZDHHC20 |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Involved in acyltransferase activity |
| Specific Function | Catalyzes palmitoylation of Cys residues on target proteins. Catalyzes palmitoylation of Cys residues in the cytoplasmic C-terminus of EGFR, and modulates the duration of EGFR signaling by modulating palmitoylation-dependent EGFR internalization and degradation. Has a preference for acyl-CoA with C16 fatty acid chains. Can also utilize acyl-CoA with C14 and C18 fatty acid chains. |
| Pathways | Not Available |
| Reactions | Not Available |
| GO Classification | Not Available |
| Cellular Location | Not Available |
| Gene Properties | |
| Chromosome Location | 12 |
| Locus | Not Available |
| SNPs | ZDHHC20 |
| Gene Sequence |
>1098 bp ATGGCGCCCTGTACGCTCTGGCGCTGCTGCCAGCGCACCGTGGGCTGGGTGCCTGTGTTG TTCATCACCTTCGTTGTCGTGTGGTCCTACTACGCGTACGTGGTGGAGCTGTGCGTGTTT ACACTTTCTGGAAATGGAGAAAACGGAAAGGCCGTTGTTTACCTTGTGGCTTTCCATCTG TTCTTTGTTATGTTTGTATGGTCCTATTGGATGACAATTTTCACATCTCCCGCTTCCCCC TCCAAAGAGTTCTGCTTGTCCAATTCTGAGAAGGAACGTTATGAAAAGGAATTCAGCCAA GAAAGACAACAAGAAATTTTGAGAAGAGCAGCAAGGGACTTACCTATCTACACCACATCG GCTTCAAAGACCGTCAGATATTGTGAAAGATGTCAGCTGATTAAGCCGGACCGTGCGCAT CACTGCTCAGCATGTGACATGTGTATTCTTAAGATGGACCATCACTGTCCTTGGGTGAAT AACTGTGTGGGATTTTCTAATTACAAATTCTTCCTGCTCTTTTTATTCTACTCTCTGTTA TATTGCCTTTTCGTGGCTACAACAGTTTTACAGTACTTCATAAAATTTTGGACGAATGAA CTCACAGATACACGTGCAAAATTCCACGTACTTTTTCTTTTCTTTGTGTCTACGATGTTC TTCATCAGCGTATTGTCACTTCTTAGCTACCACTGCTGGCTAGTTGGAAAAAACAGAACA ACCATAGAATCATTCCGTGCACCCATGTTTTCATATGGAACTGATGGAAATGGTTTCTCA CTTGGATGCAGTAAAAACTGGAGGCAAGTCTTTGGCGATGAAAAGAAATATTGGCTGCTT CCAGTATTTTCAAGCCAGGGTGACGGCTGCAGTTTTCCGACTCGCCTTGTGGGGACGGAT CCAGAGCAAGCTTCTGTCTCAAACCAAAGTGAAAGTGCCAGAAGTATTGGCTCAAATCAG CCCTTTCCTATCAAACCGCTTAGTGAATCAAAAAACCGCCTGTTGGACAGTGACCCTCAG TGGCTGGAGAGTGGATCTGAAGAAGGTGTTGGCGGATCAGGGACAAATAACCATGTAACA GTGGCAATAGAAAACTGA |
| Protein Properties | |
| Number of Residues | 365 |
| Molecular Weight | 41907.0 |
| Theoretical pI | 7.72 |
| Pfam Domain Function | Not Available |
| Signals |
|
| Transmembrane Regions |
|
| Protein Sequence |
>Probable palmitoyltransferase ZDHHC20 MAPCTLWRCCQRTVGWVPVLFITFVVVWSYYAYVVELCVFTLSGNGENGKAVVYLVAFHL FFVMFVWSYWMTIFTSPASPSKEFCLSNSEKERYEKEFSQERQQEILRRAARDLPIYTTS ASKTVRYCERCQLIKPDRAHHCSACDMCILKMDHHCPWVNNCVGFSNYKFFLLFLFYSLL YCLFVATTVLQYFIKFWTNELTDTRAKFHVLFLFFVSTMFFISVLSLLSYHCWLVGKNRT TIESFRAPMFSYGTDGNGFSLGCSKNWRQVFGDEKKYWLLPVFSSQGDGCSFPTRLVGTD PEQASVSNQSESARSIGSNQPFPIKPLSESKNRLLDSDPQWLESGSEEGVGGSGTNNHVT VAIEN |
| External Links | |
| GenBank ID Protein | AAI20295.1 |
| UniProtKB/Swiss-Prot ID | Q0VC89 |
| UniProtKB/Swiss-Prot Entry Name | ZDH20_BOVIN |
| PDB IDs | Not Available |
| GenBank Gene ID | BC120294 |
| GeneCard ID | ZDHHC20 |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| References | |
| General References | Not Available |