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| Identification |
|---|
| BMDB Protein ID
| BMDBP00256 |
| Secondary Accession Numbers
| None |
| Name
| Creatine kinase B-type |
| Synonyms
|
Not Available
|
| Gene Name
| CKB |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in ATP binding |
| Specific Function
| Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa (By similarity). |
| Pathways
|
- Arginine and Proline Metabolism
|
| Reactions
|
| Adenosine triphosphate + Creatine → ADP + Phosphocreatine |
details
|
|
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 21 |
| Locus
| Not Available |
| SNPs
| CKB |
| Gene Sequence
|
>1146 bp
ATGCCCTTCTCCAATAGCCACAACACGCTGAAGCTGCGCTTCCCGGCCGAAGATGAGTTC
CCCGACCTCAGCGGCCACAACAACCACATGGCCAAGGTGCTGACCCCCGAGCTGTACGCC
GAGCTGCGCGCTAAGAGCACTCCGAGCGGCTTCACGGTGGACGACGTCATCCAGACCGGC
GTGGACAACCCAGGCCACCCCTATATCATGACCGTGGGCTGTGTGGCCGGCGATGAGGAG
TCGTACGACGTGTTCAAAGAGCTCTTTGACCCCATCATCGAGGACCGGCACGGAGGCTAT
AAGCCCACCGACGAGCACAAGACCGACCTCAACCCCGACAACCTGCAGGGCGGCGACGAC
CTGGATCCCAACTACGTGCTGAGCTCGCGGGTGCGCACGGGCCGCAGCATCCGCGGCTTC
TGCCTCCCCCCGCACTGCAGCCGTGGGGAGCGCCGCGCCATCGAGAAGCTCGCCGTCGAA
GCCCTGTCGAGCCTGGACGGTGACCTGGCGGGGAGGTACTATGCGCTCAAAAGCATGACG
GAGGCGGAGCAGCAGCAGCTTATCGACGACCACTTCCTTTTCGATAAGCCCGTGTCGCCC
CTGCTGCTGGCTTCGGGCATGGCCCGCGACTGGCCCGACGCCCGCGGCATCTGGCATAAC
GACAATAAGACCTTCCTGGTGTGGATCAACGAGGAGGACCATCTGCGGGTCATCTCCATG
CAAAAGGGTGGCAACATGAAGGAGGTGTTCACACGCTTCTGCAACGGCCTCACCCAGATT
GAAACGCTCTTCAAGTCTAAGAACTACGAGTTCATGTGGAACCCTCACCTGGGCTACATC
CTCACCTGCCCGTCCAACCTGGGCACGGGGCTCCGGGCCGGGGTGCACATCAAGCTGCCC
CACCTGGGCAAGCACGAGAAGTTCCCCGAGGTGCTCAAGCGGCTGCGGCTTCAGAAGCGA
GGCACAGGCGGTGTGGACACGGCCGCCGTGGGCGGGGTCTTCGACGTCTCAAATGCCGAT
CGCCTGGGCTTCTCGGAGGTGGAGCTGGTGCAGATGGTGGTGGACGGTGTGAAGCTGCTC
ATCGAGATGGAGCAGCGGCTGGAGCAGGGCCAGGCCATCGATGACCTCATGCCGGCCCAG
AAGTGA
|
| Protein Properties |
|---|
| Number of Residues
| 381 |
| Molecular Weight
| 42719.0 |
| Theoretical pI
| 5.57 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
- 17-37
- 45-65
- 134-154
- 186-206
|
| Protein Sequence
|
>Creatine kinase B-type
MPFSNSHNTLKLRFPAEDEFPDLSGHNNHMAKVLTPELYAELRAKSTPSGFTVDDVIQTG
VDNPGHPYIMTVGCVAGDEESYDVFKELFDPIIEDRHGGYKPTDEHKTDLNPDNLQGGDD
LDPNYVLSSRVRTGRSIRGFCLPPHCSRGERRAIEKLAVEALSSLDGDLAGRYYALKSMT
EAEQQQLIDDHFLFDKPVSPLLLASGMARDWPDARGIWHNDNKTFLVWINEEDHLRVISM
QKGGNMKEVFTRFCNGLTQIETLFKSKNYEFMWNPHLGYILTCPSNLGTGLRAGVHIKLP
HLGKHEKFPEVLKRLRLQKRGTGGVDTAAVGGVFDVSNADRLGFSEVELVQMVVDGVKLL
IEMEQRLEQGQAIDDLMPAQK
|
| External Links |
|---|
| GenBank ID Protein
| AAX08725.1 |
| UniProtKB/Swiss-Prot ID
| Q5EA61 |
| UniProtKB/Swiss-Prot Entry Name
| KCRB_BOVIN |
| PDB IDs
|
|
| GenBank Gene ID
| BT020708 |
| GeneCard ID
| CKB |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
