Showing Protein NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial (BMDBP00305)
| Identification | |
|---|---|
| BMDB Protein ID | BMDBP00305 |
| Secondary Accession Numbers | None |
| Name | NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial |
| Synonyms | Not Available |
| Gene Name | NDUFS1 |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Energy production and conversion |
| Specific Function | Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. This is the largest subunit of complex I and it is a component of the iron-sulfur (IP) fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized. |
| Pathways | Not Available |
| Reactions | Not Available |
| GO Classification | Not Available |
| Cellular Location | Not Available |
| Gene Properties | |
| Chromosome Location | 2 |
| Locus | Not Available |
| SNPs | NDUFS1 |
| Gene Sequence |
>2184 bp OFHAEIIISITE.AGGGAGAAGTATGTTAAGGATACCTGTAAGAAAGGCCTTAGTAGGCC TTTCCAAGTCTTCTAAAGGATGTGTTCGAACAACTGCCACAGCAGCAAGCAACTTGATTG AAGTATTTGTTGATGGTCAGTCTGTCATGGTGGAACCAGGAACTACCGTCCTTCAAGCTT GTGAGAAGGTTGGCATGCAGATTCCTCGATTCTGTTATCACGAAAGGTTGTCTGTTGCTG GAAACTGCAGGATGTGCCTTGTTGAAATTGAGAAAGCTCCTAAGGTTGTAGCTGCTTGTG CCATGCCAGTAATGAAAGGTTGGAATATCCTGACAAACTCTGAGAAAACTAAGAAAGCCA GAGAAGGTGTGATGGAGTTCTTATTAGCAAATCACCCACTGGACTGTCCTATTTGTGACC AGGGAGGTGAATGTGATCTGCAGGACCAGTCCATGATGTTTGGAAGTGATAGGAGCCGGT TTTTAGAGGGGAAACGTGCTGTGGAGGACAAGAACATTGGGCCGTTGGTAAAAACCATTA TGACTAGGTGTATACAGTGTACTCGCTGCATCAGGTTTGCAAGTGAGATCGCAGGAGTGG ATGATTTGGGAACTACAGGCAGAGGAAACGATATGCAAGTTGGCACATACATTGAAAAGA TGTTCATGTCTGAACTTTCTGGCAATATCATTGACATCTGCCCTGTAGGTGCCCTGACTT CTAAGCCCTATGCCTTTACCGCTCGGCCTTGGGAAACAAGAAAGACAGAATCCATTGATG TAATGGATGCAGTTGGAAGTAATATTGTGGTCAGCACAAGAACTGGAGAGGTAATGAGGA TTTTGCCAAGGATGCATGAGGACATCAATGAAGAGTGGATCTCTGATAAAACCAGATTTG CCTATGATGGGCTAAAACGTCAAAGACTTACCGAACCGATGGTCAGAAATGAAAAGGGAC TTTTAACACATACCACCTGGGAGGATGCACTCTCTCGTGTAGCTGGAATGTTGCAGAGCT TTCAAGGCAATGATGTGGCAGCAATTGCAGGTGGCTTGGTGGATGCTGAAGCCCTCATAG CTCTCAAAGATTTACTTAATAGAGTGGATTCTGACACGCTGTGCACTGAAGAGGTCTTCC CCACCGCAGGAGCTGGCACAGATCTACGTTCCAATTATCTTCTTAATACTACAATCGCTG GTGTGGAGGAGGCAGATGTTGTCCTTCTAGTTGGTACAAATCCACGTTTTGAGGCACCGC TATTTAATGCTAGAATTCGAAAGAGCTGGCTTCATAATGACTTAAAAGTGGCCCTTATAG GCAGCCCAGTGGATCTCACTTACAGATATGACCATCTGGGAGATTCTCCCAAAATTCTTC AAGACATTGCTTCGGGTAGCCATCCATTCAGCCAGGTCCTACAGGAAGCTAAAAAACCAA TGGTGATTTTAGGCAGTTCTGCACTCCAAAGAAATGATGGTGCAGCAATTCTTGCAGCTG TTTCCAACATTGCTCAGAAGATTCGGACAAGTAGTGGTGTTACTGGTGATTGGAAAGTTA TGAATATCCTTCATAGGATTGCAAGCCAAGTAGCTGCTTTGGATCTTGGCTATAAGCCTG GGGTGGAAGCAATTCAGAAGAATCCTCCTAAAATGCTGTTTCTCCTGGGAGCAGATGGAG GTTGTATCACTCGACAGGATTTGCCAAAGGATTGTTTCATTGTTTATCAAGGACATCATG GCGACGTCGGAGCTCCTATAGCTGATGTTATTCTCCCTGGCGCTGCTTACACAGAGAAGT CTGCTACTTACGTCAATACCGAGGGCCGAGCTCAGCAGACAAAAGTAGCAGTGACGCCTC CCGGCTTGGCAAGAGAAGACTGGAAAATTATAAGAGCCCTTTCTGAGATTGCAGGTATGA CTCTTCCATATGATACTCTGGATCAAGTGAGAAACAGATTGGAAGAAGTCTCTCCTAATC TTGTTCGATATGATGATGTTGAAGGAGCTAATTATTTCCAGCAAGCAAGTGAGCTTTCCA AGCTAGTGAACCAACAGCTTCTTGCTGATCCACTTGTTCCACCTCAGCTAACAATAAAAG ACTTCTACATGACAGATTCAATTAGCAGAGCCTCACAGACAATGGCTAAATGTGTCAAAG CTGTTACAGAGGGTGCCCATGCAG |
| Protein Properties | |
| Number of Residues | 727 |
| Molecular Weight | 79442.0 |
| Theoretical pI | 6.03 |
| Pfam Domain Function | Not Available |
| Signals |
|
| Transmembrane Regions |
|
| Protein Sequence |
>NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial MLRIPVRKALVGLSKSSKGCVRTTATAASNLIEVFVDGQSVMVEPGTTVLQACEKVGMQI PRFCYHERLSVAGNCRMCLVEIEKAPKVVAACAMPVMKGWNILTNSEKTKKAREGVMEFL LANHPLDCPICDQGGECDLQDQSMMFGSDRSRFLEGKRAVEDKNIGPLVKTIMTRCIQCT RCIRFASEIAGVDDLGTTGRGNDMQVGTYIEKMFMSELSGNIIDICPVGALTSKPYAFTA RPWETRKTESIDVMDAVGSNIVVSTRTGEVMRILPRMHEDINEEWISDKTRFAYDGLKRQ RLTEPMVRNEKGLLTHTTWEDALSRVAGMLQSFQGNDVAAIAGGLVDAEALIALKDLLNR VDSDTLCTEEVFPTAGAGTDLRSNYLLNTTIAGVEEADVVLLVGTNPRFEAPLFNARIRK SWLHNDLKVALIGSPVDLTYRYDHLGDSPKILQDIASGSHPFSQVLQEAKKPMVILGSSA LQRNDGAAILAAVSNIAQKIRTSSGVTGDWKVMNILHRIASQVAALDLGYKPGVEAIQKN PPKMLFLLGADGGCITRQDLPKDCFIVYQGHHGDVGAPIADVILPGAAYTEKSATYVNTE GRAQQTKVAVTPPGLAREDWKIIRALSEIAGMTLPYDTLDQVRNRLEEVSPNLVRYDDVE GANYFQQASELSKLVNQQLLADPLVPPQLTIKDFYMTDSISRASQTMAKCVKAVTEGAHA VEEPSIC |
| External Links | |
| GenBank ID Protein | AAA30662.1 |
| UniProtKB/Swiss-Prot ID | P15690 |
| UniProtKB/Swiss-Prot Entry Name | NDUS1_BOVIN |
| PDB IDs | |
| GenBank Gene ID | J02877 |
| GeneCard ID | NDUFS1 |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| References | |
| General References | Not Available |